Search results for "LAB"
showing 10 items of 7932 documents
Two New Alternatives to the Conventional Arm-in-Cage Test for Assessing Topical Repellents
2021
Abstract European guidelines for testing attractant and repellent efficacy (i.e., Product type 19 [PT19]) have been in revision since 2017. A key topic of discussion is the current approach to evaluating topical repellents. The European Chemical Agency has stated field testing should be avoided because of mosquito-borne disease risks. However, the most common laboratory method, the arm-in-cage (AIC) test, may limit the reliable extrapolation of lab results to field conditions. This study’s main goal was to assess alternative laboratory methods for evaluating topical mosquito repellents that use mosquito landing rates more representative of those in the field. The study took place at three E…
An in-depth evaluation of acalabrutinib for the treatment of mantle-cell lymphoma
2020
Introduction: Regimens involving intensive immuno-chemotherapy, followed by high-dose therapy and autologous stem cell transplant represent the standard treatment for younger fit patients with mantle cell lymphoma (MCL). Targeted approaches (i.e. ibrutinib, bortezomib, and lenalidomide) represent the backbone of therapy for relapsed cases. Areas covered: Acalabrutinib is a novel small molecule with a butynamide moiety specifically designed to irreversibly inhibit Bruton tyrosine kinase (BTK), which is more potent and selective than ibrutinib. Relevant publications have been identified through literature searches using the terms 'mantle cell lymphoma' and 'acalabrutinib'. Expert opinion: Aca…
Improve Your Social Network and Have the Advantage in the Employment Seeking Process
2021
Human resource management uses social networks to identify new employees. This research investigates if people use social networks to identify employment opportunities and how they improve their networks to get easier and quicker access to information and resources. Researchers worldwide devote their attention to different aspects of identification of new employees via social networks. The authors of the paper have done empirical research based on an online survey with 298 respondents, and the data obtained from the survey has been analysed using various statistical tools. The number of suitable candidates for employment is decreasing and companies need knowledge about the employment seekin…
Comparación de dos métodos de evaluación simplificada del riesgo químico por inhalación en un laboratorio universitario (COSHH Essentials y método ba…
2016
En conclusión, hemos comprobado que ambos métodos pueden ser un recurso sencillo para planificar la prevención en entornos laborales con riesgo químico. El método basado en el INRS contempla más determinantes del riesgo que el COSHH Essentials, pero las características dispares de ambos métodos deben determinar la mejor elección para cada situación; o incluso, como sugieren nuestros resultados, su utilización complementaria. Se debe añadir que, "es razonable iniciar el proceso de evaluación con un análisis cualitativo, a pesar de que, en muchas ocasiones no es posible alcanzar conclusiones sobre el riesgo y es necesario realizar una evaluación cuantitativa"; también sería recomendable, ante…
Carbonate/evaporitic sedimentation during the Messinian salinity crisis in active accretionary wedge basins of the northern Calabria, southern Italy
2020
Abstract This work deals with Messinian deposits belonging to the Neogene infill of the Rossano and Belvedere Basins, respectively developed along the fore-arc and the back-arc areas of the north Calabria accretionary wedge. The main goal is to characterize the carbonate and evaporitic sedimentation during the Messinian Salinity Crisis, in the general framework of the basin architecture and the interplay between eustatic vs tectonic controlled sea-level variations. Fieldwork integrated with seismic lines and well logs interpretations led to the revision of the general stratigraphy of the basins and the proposal of a new sequential stratigraphic model driven by cyclic sea-level variations. E…
Avoiding accidents at the champagne reception: A study of joint lifting and balancing
2017
Using a lifting and balancing task, we contrasted two alternative views of planning joint actions: one postulating that joint action involves distinct predictions for self and other, the other postulating that joint action involves coordinated plans between the coactors and reuse of bimanual models. We compared compensatory movements required to keep a tray balanced when 2 participants lifted glasses from each other’s trays at the same time (simultaneous joint action) and when they took turns lifting (sequential joint action). Compared with sequential joint action, simultaneous joint action made it easier to keep the tray balanced. Thus, in keeping with the view that bimanual models are reu…
Pefloxacine mesilate- and ofloxacin-loaded polyethylcyanoacrylate nanoparticles: characterization of the colloidal drug carrier formulation.
1995
The entrapment of fluoroquinolones, perfloxacine mesilate (PFX) and ofloxacin (OFX), in polyalkylcyanoacrylate (PECA) nanoparticles could offer some advantages for their biological application; for examples, increasing their bioavailability, controlling the drug time-release in blood, and reducing the formation of bacterial resistance. To load these two drugs in PECA polymeric bulk, the incorporation or adsorption method was performed. These two methods were capable of influencing nanoparticle size, molecular weight, release profile, and drug–polymer association. The incorporation method, particularly for the OFX system, achieved PECA nanoparticle suspensions with a mean size value three ti…
Le politiche del lavoro e i servizi per l'impiego: eredità passate e opportunità di innovazione
2017
Il programma europeo della Garanzia Giovani rivolto ai giovani Neet rappresenta una potenziale opportunità di innovazione delle politiche attive del lavoro. Tuttavia, la sua attuazione in Italia è stata accolta con molta preoccupazione in ragione dello stato dei servizi pubblici per l’impiego, che nelle regioni del sud non sono mai riusciti ad abbandonare la logica burocratico-certificatoria del vecchio collocamento. Questo lavoro presenta i dati di una ricerca svolta in Sicilia, una fra le regioni italiane più problematiche, con riferimento sia alle condizioni del mercato del lavoro, sia ai rendimenti istituzionali in materia di politiche per il lavoro. Nonostante le premesse tutt’altro ch…
The Study of the Scale through Space. Teaching Innovation Experience among Architecture Schools: Malaga, Seville and Palermo
2018
The educational innovation project object of this communication focuses on the scale problems that arise in the projects of territorial planning carried out in architecture schools, but also in the loss of the scale concept related to thought and drawing. The project involved collaboration among the Schools of Architecture of Malaga, Palermo and Seville with the aim of carrying out a practical exercise among the students of two subjects that, working on different scales, addressed similar concepts. In particular, following an PBL methodology based on collaborative projects, the planning of the N-340 road in the city of Nerja (Málaga) was carried out. Firstly, the territorial scale is addres…
Active deformation evidence in the offshore of western Calabria (southern Tyrrhenian Sea) from ultra-resolution multichannel seismic reflection data:…
2020
<p>An ultra-resolution, multichannel seismic reflection data set was collected during an oceanographic cruise organised in the frame of the “<em>Earthquake Potential of Active Faults using offshore Geological and Morphological Indicators</em>” (EPAF) project, which was founded by the Scientific and Technological Cooperation (Scientific Track 2017) between the Italian Ministry of Foreign Affairs and International Cooperation and the Ministry of Science, Technology and Space of the State of Israel. The data acquisition approach was based on innovative technologies for the offshore imaging of stratigraphy and structures alo…