Search results for "LAB"

In vitro fertilization and andrology laboratory in 2030: expert visions.

2021

The aim of this article is to gather 9 thought leaders and their team members to present their ideas about the future of in vitro fertilization and the andrology laboratory. Although we have seen much progress and innovation in the laboratory over the years, there is still much to come, and this article looks at what these leaders think will be important in the future development of technology and processes in the laboratory.

Semiautomatic growth analysis of multicellular tumor spheroids.

2011

Multicellular tumor spheroids (MCTS) are routinely employed as three-dimensional in vitro models to study tumor biology. Cultivation of MCTS in spinner flasks provides better growing conditions, especially with regard to the availability of nutrients and oxygen, when compared with microtiter plates. The main endpoint of drug response experiments is spheroid size. It is common practice to analyze spheroid size manually with a microscope and an ocular micrometer. This requires removal of some spheroids from the flask, which entails major limitations such as loss of MCTS and the risk of contamination. With this new approach, the authors present an efficient and highly reproducible method to an…

A Case Study on Vestibular Sensations in Driving Simulators.

2022

Motion platforms have been used in simulators of all types for several decades. Since it is impossible to reproduce the accelerations of a vehicle without limitations through a physically limited system (platform), it is common to use washout filters and motion cueing algorithms (MCA) to select which accelerations are reproduced and which are not. Despite the time that has passed since their development, most of these algorithms still use the classical washout algorithm. In the use of these MCAs, there is always information that is lost and, if that information is important for the purpose of the simulator (the training simulators), the result obtained by the users of that simulator will no…

Quotients of the Dwork Pencil

2012

In this paper we investigate the geometry of the Dwork pencil in any dimension. More specifically, we study the automorphism group G of the generic fiber of the pencil over the complex projective line, and the quotients of it by various subgroups of G. In particular, we compute the Hodge numbers of these quotients via orbifold cohomology.

Groups acting freely on Calabi-Yau threefolds embedded in a product of del Pezzo surfaces

2011

In this paper, we investigate quotients of Calabi-Yau manifolds $Y$ embedded in Fano varieties $X$, which are products of two del Pezzo surfaces — with respect to groups $G$ that act freely on $Y$. In particular, we revisit some known examples and we obtain some new Calabi-Yau varieties with small Hodge numbers. The groups $G$ are subgroups of the automorphism groups of $X$, which is described in terms of the automorphism group of the two del Pezzo surfaces.

Medicīnas ētikas principi intensīvās terapijas nodaļā pacientu skatījumā

2021

Bakalaura darba tēma “Medicīnas ētikas principi intensīvās terapijas nodaļā pacientu skatījumā”. Tēmas aktualitāti nosaka tas, ka mūsdienu veselības aprūpē jāuztur augsts ētikas standarts, it īpaši, lai palīdzētu veselības aprūpes speciālistiem un organizācijām virzīties uz šiem standartiem, kā arī pacientu aizsardzību, kuru var ietekmēt veselības aprūpes speciālistu uzvedība. Tādējādi, medicīnas ētikas principu ievērošana, nosakot uzvedības standartus, saizsargā ne tikai pacientus, bet arī veselības aprūpes sniedzējus un iestādes, kā arī veicina pacientu, profesionālo kolēģu un visas sabiedrības uzticību. Darba mērķis ir noskaidrot pacientu skatījumu par medicīnas ētikas principiem intensī…

Autoveikala darbība Ziemeļkurzemes reģionā. Laika, telpas un sociālo, ekonomisko procesu izpēte

2016

Bakalaura darbs “Autoveikala darbība Ziemeļkurzemes reģionā. Laika, telpas sociālo un ekonomisko procesu izpēte” ir pētījums par veikalu uz riteņiem, kurš trīsdesmit gadus piegādā lauku iedzīvotājiem pārtiku, pievedot to pie mājām vai ciema centros. Autoveikalam ir izdevies ekonomiski mainīgajos apstākļos izdzīvot un turpināt savu darbību. Šī pakalojuma rezultātā ir vērojami vietējo dzīves apstākļi Latvijas laukos, sabiedriskās dzīves organizēšana, un tā ekonomiskā racionalitāte kā tirdzniecības punktam. Pētījuma mērķis- noskaidrot kā autoveikala darbība atspoguļo tā klientu iespējas un ikdienas norises laukos, Ziemeļkurzemes reģionā. Pētījuma rezultāti liecina, ka autoveikala klientūra ir …

Efficient techniques for energy saving in data center networks

2018

Data centers are constructed with a huge number of network devices to support the expanding cloud based services. These devices are used to achieve the highest performance in case of full utilization of the network. However, the peak capacity of the network is rarely reached. Consequently, many devices are set into idle state and cause a huge energy waste leading to a non-proportionality between the network load and the energy consumed. In this paper, we propose a new approach to improve the efficiency of data centers in terms of energy consumption. Our approach exploits the correlation in time of the inter-node communication traffic and some topological features to maximize energy saving w…

The Low-Affinity ATP Binding Site of the Escherichia coli SecA Dimer Is Localized at the Subunit Interface

1997

The homodimeric SecA protein is the ATP-dependent force generator in the Escherichia coli precursor protein translocation cascade. SecA contains two essential nucleotide binding sites (NBSs), i.e., NBS1 and NBS2 that hind ATP with high and low affinity, respectively. The photoactivatable bifunctional cross-linking agent 3'-arylazido-8-azidoadenosine 5'-triphosphate (diN(3)ATP) was used to investigate the spatial arrangement of the nucleotide binding sites of SecA, DiN(3)ATP is an authentic ATP analogue as it supports SecA-dependent precursor protein translocation and translocation ATPase, UV-induced photo-cross-linking of the diN(3)ATP-bound SecA results in the formation of stable dimeric s…

1986

The terpolymerization of the three monomers (3-vinyl phenylazo)methylmalodinitrile (1), (3-vinyl phenylazo)phenylsulfid (2) or 1-(3-vinylphenylazo)-1,1′-diphenyl methylacetate (3) with methyl methacrylate and butanediol-1,4-dimethyacrylate leads to networks in which the thermolabile azo groups remain intact. Both, the azo monomer and the crosslinking agent are essentially quantitatively incorporated into the network before the conversion of the third monomer is complete. The networks have been characterized in terms of their swelling in benzene, chlorobenzene, and methacrylonitrile. Die Terpolymerisation der drei Monomeren (3-Vinylphenylazo)-methylmalodinitril (1), (3-Vinylphenylazo)phenyls…