Search results for "LABOR"

Differential modulation and prognostic values of immune-escape genes in uveal melanoma

2019

Uveal melanoma (UM) is the most common primary intraocular cancer in adults. In the present study, we aimed to characterize the immunological features of primary UM cancer and to provide an association with prognostic markers and outcome. Also, we assessed the influence of the microenvironment on the expression of inhibitory immune checkpoints in UM. Genes of interest included MHC Class I and Class II molecules, as well as inhibitory immune-checkpoints, i.e. PDL1, PDL2, B7-H3, B7-H4, TBFRSF6B, CD47, CD155, GAL9, HVEM and CD200. We observed significant lower levels of MHC genes in UM cells as compared to normal uveal melanocytes. Unexpectedly however, the expression levels of most of the ana…

Simulating music with associative self-organizing maps

2018

Abstract We present an architecture able to recognise pitches and to internally simulate likely continuations of partially heard melodies. Our architecture consists of a novel version of the Associative Self-Organizing Map (A-SOM) with generalized ancillary connections. We tested the performance of our architecture with melodies from a publicly available database containing 370 Bach chorale melodies. The results showed that the architecture could learn to represent and perfectly simulate the remaining 20% of three different interrupted melodies when using a context length of 8 centres of activity in the A-SOM. These promising and encouraging results show that our architecture offers somethi…

Self-regulation Training and Job Search Behavior: A Natural Field Experiment Within an Active Labor Market Program

2019

Recent evidence suggests that self-regulation abilities play an important role for the job finding success of unemployed persons. We conduct a randomized controlled trial embedded in an established labor market reactivation program to examine the effect of a self-regulation training on job search effort of long-term unemployed participants. Our treatment involves teaching a self-regulation strategy based on mental contrasting with implementation intentions. We find that the treatment has a positive effect on the quality of application documents as well as on the probability of participants submitting their documents on time. However, we do not find a significant positive effect on labor mar…

Labour market segmentation in Spain: is legislation leading to a reduction of duality?

2016

Abstract: In the last decades, the Spanish legislature has expressed its concern regarding the negative impact of the existing duality in its national labour market. Many of the employment Acts adopted in the last few years specifically mention this problem in their preambles. In order to analyse the effectiveness of the measures adopted about this question it is necessary to highlight the two different ways to approach the problem of duality. On the one hand, the existing dual- ity could be reduced by making the access to temporary contacts of employment harder (reducing the number and the possibilities of temporary contracts and increasing the labour cost of these contracts) On the other …

Lula, en un pais dependiente

2002

DeepSRE: Identification of sterol responsive elements and nuclear transcription factors Y proximity in human DNA by Convolutional Neural Network anal…

2021

SREBP1 and 2, are cholesterol sensors able to modulate cholesterol-related gene expression responses. SREBPs binding sites are characterized by the presence of multiple target sequences as SRE, NFY and SP1, that can be arranged differently in different genes, so that it is not easy to identify the binding site on the basis of direct DNA sequence analysis. This paper presents a complete workflow based on a one-dimensional Convolutional Neural Network (CNN) model able to detect putative SREBPs binding sites irrespective of target elements arrangements. The strategy is based on the recognition of SRE linked (less than 250 bp) to NFY sequences according to chromosomal localization derived from …

Scaling carbon fluxes from eddy covariance sites to globe: synthesis and evaluation of the FLUXCOM approach

2020

FLUXNET comprises globally distributed eddy-covariance-based estimates of carbon fluxes between the biosphere and the atmosphere. Since eddy covariance flux towers have a relatively small footprint and are distributed unevenly across the world, upscaling the observations is necessary to obtain global-scale estimates of biosphere–atmosphere exchange. Based on cross-consistency checks with atmospheric inversions, sun-induced fluorescence (SIF) and dynamic global vegetation models (DGVMs), here we provide a systematic assessment of the latest upscaling efforts for gross primary production (GPP) and net ecosystem exchange (NEE) of the FLUXCOM initiative, where different machine learning methods…

Spectrodirectional Minnaert-kretrieval using CHRIS-PROBA data

2010

We report on a detailed analysis of hyperspectral and multidirectional remote sensing data acquired using the Compact High Resolution Imaging Spectrometer (CHRIS) mounted onboard the Project for On-Board Autonomy (PROBA) spacecraft. This instrument is capable of sampling reflected radiation over the visible and near-infrared (NIR) region of the solar spectrum at a spatial resolution (approx. 17 m) intermediary between sensors traditionally used in land applications (such as Landsat and Satellite Pour l’Observation de la Terre (SPOT), 30 m–50 m) and the latest instruments delivering a nominal resolution of 1 m or less. The spectral anisotropic signature of an Alpine coniferous forest during …

Experimental Analysis of Horizontal Turbulence of Flow over Flat and Deformed Beds

2015

Abstract Laboratory experiments in a straight flume were carried out to examine the evolution of large-scale horizontal turbulent structures under flat-bed and deformed-bed conditions. In this paper, the horizontal turbulence of flow under these conditions is analyzed and compared. The conditioned quadrant method is applied to verify the occurrence of turbulent events. The distributions of horizontal Reynolds shear stress and turbulent kinetic energy are also presented and discussed. Results show the occurrence of an “initial” sequence of horizontal vortices whose average spatial length scales with the channel width. Under deformed-bed conditions, this spatial length does not change.

Patented and commercialized applications

2021

Abstract The commercialization of high added-value compounds recovery from food wastes deals with several issues such as laboratory research, scale-up problems, protection of intellectual properties, and development of market-destined applications. These issues are described in this chapter wherein a collection of commercially available compounds recovered from food by-products is presented. Verification of market existing products matching with patented processes was conducted using patent applicant name in each case. However, this matching as well as production characteristics may not be correct in all cases, as most companies typically are secretive about their methods of production and …