Search results for "LABOR"

showing 10 items of 3876 documents

Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins

2021

Antiphospholipid antibodies (aPL), assumed to cause antiphospholipid syndrome (APS), are notorious for their heterogeneity in targeting phospholipids and phospholipid-binding proteins. The persistent presence of Lupus anticoagulant and/or aPL against cardiolipin and/or β2-glycoprotein I have been shown to be independent risk factors for vascular thrombosis and pregnancy morbidity in APS. aPL production is thought to be triggered by–among other factors–viral infections, though infection-associated aPL have mostly been considered non-pathogenic. Recently, the potential pathogenicity of infection-associated aPL has gained momentum since an increasing number of patients infected with Severe Acu…

RNA virusesPulmonologyCoronavirusesPhysiology2405 ParasitologyAntibody Response030204 cardiovascular system & hematologyBiochemistrychemistry.chemical_compoundMedical Conditions0302 clinical medicineimmune system diseasesImmune PhysiologyMedicine and Health SciencesCardiolipinMedicineBiology (General)skin and connective tissue diseasesImmune ResponsePathology and laboratory medicineCOVIDVirus Testing0303 health sciencesLupus anticoagulantImmune System Proteinsbiologymedicine.diagnostic_test2404 MicrobiologyProteasesMedical microbiologyEnzymes3. Good healthInfectious DiseasesCoagulationVirusesSARS CoV 2PathogensAntibodyResearch ArticleSARS coronavirusQH301-705.5Immunology10208 Institute of Neuropathology610 Medicine & healthSARS-CoV-2; Respiratory infections; Virus testing; serine proteases; Antibody response; Autoantibodies; Blood plasma; ImmunoassaysResearch and Analysis MethodsMicrobiologyAntibodiesRespiratory Disorders03 medical and health sciences1311 GeneticsDiagnostic MedicineAntiphospholipid syndromeVirology1312 Molecular BiologyGeneticsImmunoassaysneoplasmsMolecular BiologyAutoantibodies030304 developmental biology030203 arthritis & rheumatology2403 ImmunologyPregnancyBiology and life sciencesbusiness.industryOrganismsViral pathogensAutoantibodyProteinsRC581-607medicine.diseaseMicrobial pathogenschemistry19ImmunoassayRespiratory InfectionsImmunology2406 VirologyEnzymologyImmunologic Techniquesbiology.protein570 Life sciences; biologyParasitologyImmunologic diseases. AllergySerine ProteasesbusinessPLOS Pathogens
researchProduct

Risk factors for gastroenteritis associated with canal swimming in two cities in the Netherlands during the summer of 2015: A prospective study

2017

Urban canal swimming events are popular in the Netherlands. In 2015, two city canal swimming events took place, in Utrecht (Utrecht Singel Swim, USS) and in Amsterdam (Amsterdam City Swim, ACS). This prospective study characterizes the health risks associated with swimming in urban waters. Online questionnaires were sent to 160 (USS) and 2,692 (ACS) participants, with relatives of participants who did not swim completing the questionnaire as a control. Swimming water specimens and stool specimens of diarrheic participants in the ACS group were analysed. A total of 49% of USS and 51% of ACS swimmers returned their questionnaires. Nine percent of USS swimmers and 4% of non-swimmers reported g…

RNA virusesQuestionnaires0301 basic medicineMalePediatricsPhysiologyWater contaminationlcsh:MedicineFresh WaterPathology and Laboratory Medicinemedicine.disease_causeDisease OutbreaksFecesRisk FactorsSurveys and QuestionnairesWater QualityEpidemiologyMedicine and Health SciencesProspective StudiesProspective cohort studylcsh:ScienceCaliciviridae InfectionsNetherlandsMultidisciplinarySewageEnterobacteriaceae InfectionsMiddle AgedBacterial PathogensGastroenteritisMedical MicrobiologyResearch DesignViral PathogensVirusesEngineering and TechnologyFemalePathogensAnatomyWater MicrobiologyResearch ArticleAdultmedicine.medical_specialtyEnvironmental EngineeringAdolescent030106 microbiologyResearch and Analysis MethodsMicrobiologyCaliciviruses03 medical and health sciencesYoung AdultEnterobacteriaceaeSurface WaterEnvironmental healthmedicineHumansMicrobial PathogensSwimmingSurvey ResearchBacteriaBiological Locomotionbusiness.industryNorovirusWater Pollutionlcsh:ROrganismsBiology and Life SciencesOutbreakGastrointestinal TractEarth SciencesNoroviruslcsh:QHydrologybusinessDigestive SystemEnterococcus
researchProduct

Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens

2019

25 Páginas, 7 figuras, 2 tablas

RNA virusesRotavirusViral DiseasesPhysiologyViral Nonstructural ProteinsPathology and Laboratory MedicineCrystallography X-Raymedicine.disease_causeBiochemistryBinding AnalysisReovirusesImmune PhysiologyRotavirusMedicine and Health SciencesChemical PrecipitationBiology (General)Antigens ViralGastroenterologiachemistry.chemical_classification0303 health sciencesImmune System ProteinsCrystallographyMolecular StructurebiologyPhysics030302 biochemistry & molecular biologyChemical ReactionsRNA-Binding ProteinsCondensed Matter PhysicsLigand (biochemistry)Amino acidChemistryInfectious DiseasesMedical MicrobiologyViral PathogensVirusesPhysical SciencesCrystal StructurePathogensCrystallizationResearch ArticleChemical ElementsGlycanQH301-705.5Virus RNAViral proteinImmunologyResearch and Analysis MethodsMicrobiologyABO Blood-Group SystemCell Line03 medical and health sciencesAntigenVirologyGeneticsmedicineSolid State PhysicsHumansAntigensBinding siteMicrobial PathogensMolecular BiologyRotavirus InfectionChemical Characterization030304 developmental biologyChemical PhysicsBinding SitesBiology and life sciencesMutagenesisOrganismsProteinsRC581-607Molecular biologyCarbonchemistrybiology.proteinCapsid ProteinsParasitologyImmunologic diseases. AllergyPLOS Pathogens
researchProduct

Investigation of superspreading COVID-19 outbreak events in meat and poultry processing plants in Germany: A cross-sectional study.

2020

Since May 2020, several COVID-19 outbreaks have occurred in the German meat industry despite various protective measures, and temperature and ventilation conditions were considered as possible high-risk factors. This cross-sectional study examined meat and poultry plants to examine possible risk factors. Companies completed a self-administered questionnaire on the work environment and protective measures taken to prevent SARS-CoV-2 infection. Multivariable logistic regression analysis adjusted for the possibility to distance at least 1.5 meters, break rules, and employment status was performed to identify risk factors associated with COVID-19 cases. Twenty-two meat and poultry plants with 1…

RNA virusesViral DiseasesMeat packing industryCross-sectional studyEconomicsCoronavirusesSocial SciencesLogistic regressionPoultrylaw.inventionDisease OutbreaksMedical ConditionslawRisk FactorsAnimal ProductsGermanyMedicine and Health SciencesMedicineFood IndustryPublic and Occupational HealthWorkplacePathology and laboratory medicineVirus TestingMultidisciplinaryPhysicsQRTemperatureClassical MechanicsEukaryotaAgriculturePoultry farmingMedical microbiologyDynamicsMeat ProductsInfectious DiseasesAir FlowVentilation (architecture)VirusesPhysical SciencesVertebratesMedicineSARS CoV 2PathogensResearch ArticleEmploymentPhysics - Physics and SocietyMeatCoronavirus disease 2019 (COVID-19)SARS coronavirusScienceFOS: Physical sciencesPhysics and Society (physics.soc-ph)MicrobiologyBirdsAerodynamicsDiagnostic MedicineEnvironmental healthHumansAnimalsNutritionbusiness.industrySARS-CoV-2OrganismsViral pathogensOutbreakCOVID-19Biology and Life SciencesCovid 19Odds ratioPhysics - Medical PhysicsVentilationDietMicrobial pathogensCross-Sectional StudiesFoodLabor EconomicsAmniotesMedical Physics (physics.med-ph)businessZoologyPloS one
researchProduct

Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage

2021

The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular protein kinases and other signaling proteins. A canonical SH3 domain binding motif in Nef is required for most of these interactions. For example, HIV-1 Nef activates the tyrosine kinase Hck by tightly binding to its SH3 domain. An archetypal contact between a negatively charged SH3 residue and a highly conserved arginine in Nef (Arg77) plays a key role here. Combining structural analyses with functional assays, we here show that Nef proteins have also developed a distinct structural strategy—termed the "R-clamp”—that favors the formation …

RNA virusesviruksetvirusesSimian Acquired Immunodeficiency SyndromeHIV InfectionsPathology and Laboratory MedicineSH3 domainWhite Blood CellsImmunodeficiency VirusesAnimal CellsMedicine and Health SciencesBiology (General)MammalsGenetics11832 Microbiology and virology0303 health sciencesKinase030302 biochemistry & molecular biologyEukaryotavirus diseasesTransfection3. Good healthSIVMedical MicrobiologyViral PathogensViral evolutionVirusesVertebratesProto-Oncogene Proteins c-hckApesSimian Immunodeficiency VirusPathogensCellular TypesTyrosine kinaseResearch ArticlePrimateskinaasitEvolutionary ImmunologyLineage (genetic)QH301-705.5Immune CellsImmunologyevoluutioBiologyTransfectionResearch and Analysis MethodsHIV-tartuntaMicrobiologyViral EvolutionEvolution Molecularsrc Homology Domains03 medical and health sciencesVirologyRetrovirusesGeneticsAnimalsHumansLuciferaseAmino Acid Sequencenef Gene Products Human Immunodeficiency VirusChimpanzeesMolecular Biology TechniquesMicrobial PathogensMolecular Biology030304 developmental biologyEvolutionary BiologyBlood CellsSequence Homology Amino AcidMacrophagesLentivirusOrganismsBiology and Life SciencesHIVCell BiologyRC581-607Organismal Evolution3121 General medicine internal medicine and other clinical medicineMicrobial EvolutionAmniotesHIV-1ParasitologySalt bridgeproteiinitImmunologic diseases. AllergyZoology
researchProduct

Racconti in cattedra. Realizzati dagli alunni del Laboratorio di Scrittura Italiana. Corso tenuto dal prof. Antonio Fundarò. Anno Accademico 2007-2008

2008

Racconti realizzanti dagli studenti de Corso di Laboratorio di Scrittura Italiana tenuto nell'Anno Accademico 2007-2008Settore L-FIL-LET/10 - Letteratura Italiana
researchProduct

Introduzione a Vitaliano Brancati, Tutti i racconti, a cura di Domenica Perrone

2018

La raccolta di "Tutti racconti "di Brancati consente di ripercorrere, attraverso la narrativa breve , l'intera parabola intellettuale dell'autore del "Don Giovanni in Sicilia". Dal laboratorio giovanile fino alla disincantata analisi dell'IItalia del dopoguerra. Si offre al lettore così un'avventura letteraria alimentata da una costante tensione morale che si coniuga, spesso attraverso una fine ironia, con il rilievo esistenziale.

Racconti laboratorio malinteso illusione delusione noia realtà sogno.
researchProduct

Seeking the Holy Grail: robust chronologies from archaeology and radiocarbon dating combined

2018

The strengths of formal Bayesian chronological modelling are restated, combining as it does knowledge of the archaeology with the radiocarbon dating of carefully chosen samples of known taphonomy in association with diagnostic material culture. The risks of dating bone samples are reviewed, along with a brief history of the development of approaches to the radiocarbon dating of bone. In reply to Strien (2017), selected topics concerned with the emergence and aftermath of the LBK are discussed, as well as the early Vinča, Ražište and Hinkelstein sequences. The need for rigour in an approach which combines archaeology and radiocarbon dating is underlined.

Radiocarbon dating010506 paleontologyArcheologyRa∫i∏teVin≠a01 natural sciencesearliest LBK0601 history and archaeologylaboratory methodsBayesian chronological mod- ellingTheologyVinča0105 earth and related environmental sciences060102 archaeologyHinkelsteinradiocarbon datingBayesian chronological modelling06 humanities and the artsbone samplesHoly GrailAnthropologyBone samplesLaboratory methodsRažišteGeologyEarliest LBK
researchProduct

A fully automatic approach for multimodal PET and MR image segmentation in gamma knife treatment planning

2017

The aim of this study is to combine Biological Target Volume (BTV) segmentation and Gross Target Volume (GTV) segmentation in stereotactic neurosurgery.Our goal is to enhance Clinical Target Volume (CTV) definition, including metabolic and morphologic information, for treatment planning and patient follow-up.We propose a fully automatic approach for multimodal PET and MR image segmentation. This method is based on the Random Walker (RW) and Fuzzy C-Means clustering (FCM) algorithms. A total of 19 brain metastatic tumors, undergone stereotactic neuro-radiosurgery, were retrospectively analyzed. A framework for the evaluation of multimodal PET/MRI segmentation is presented, considering volume…

Radiotherapy PlanningBrain tumorHealth Informatics02 engineering and technologyFuzzy C-means clusteringRadiosurgeryBrain tumorsMultimodal ImagingING-INF/05 - SISTEMI DI ELABORAZIONE DELLE INFORMAZIONI030218 nuclear medicine & medical imaging03 medical and health sciencesComputer-Assisted0302 clinical medicineRandom walker algorithm0202 electrical engineering electronic engineering information engineeringHumansMedicineSegmentationComputer visionRadiation treatment planningCluster analysisImage resolutionPET/MR imagingModality (human–computer interaction)Brain Neoplasmsbusiness.industryRadiotherapy Planning Computer-AssistedINF/01 - INFORMATICAMultimodal therapymedicine.diseaseRandom Walker algorithmMagnetic Resonance ImagingComputer Science ApplicationsBrain tumorGamma knife treatmentPositron-Emission Tomography020201 artificial intelligence & image processingMultimodal image segmentationBrain tumors; Fuzzy C-means clustering; Gamma knife treatments; Multimodal image segmentation; PET/MR imaging; Random Walker algorithm; Brain Neoplasms; Humans; Radiosurgery; Magnetic Resonance Imaging; Multimodal Imaging; Positron-Emission Tomography; Radiotherapy Planning Computer-AssistedArtificial intelligencebusinessGamma knife treatmentsSoftware
researchProduct

Radon and material radiopurity assessment for the NEXT double beta decay experiment

2015

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM

Radon mitigationPhysics - Instrumentation and DetectorsNuclear engineeringchemistry.chemical_elementFOS: Physical sciencesRadon7. Clean energy01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)XenonCambres d'ionitzacióDouble beta decayGamma detectors (HPGe)0103 physical sciencesGamma spectroscopyNuclear Experiment (nucl-ex)010306 general physicsNuclear ExperimentDetectors de radiació010308 nuclear & particles physicsIonization chambersCanfranc Underground LaboratoryMaterial radiopurityFísicaTime-Projection Chamber (TPC)Instrumentation and Detectors (physics.ins-det)Double beta decaySemiconductor detectorchemistry13. Climate actionNuclear countersEnvironmental scienceNeutrino
researchProduct