Search results for "LAP"

showing 10 items of 3898 documents

Hypoplasia of the posterior mitral valve leaflet: Don't forget to look beyond the mitral valve.

2020

Hypoplasia of the posterior mitral valve leaflet (PMVL) is a very rare finding in adulthood and can coexist with other congenital heart defects. In this image, a transesophageal echocardiography (TOE) carried out on a 59-year-old woman with a 2-month history of dyspnea revealed a hypoplastic PMVL causing severe mitral regurgitation associated with a secundum-type atrial septal defect (ASD) with left-to-right shunting. This case demonstrates how essential 3-dimensional TOE is for a comprehensive assessment of the mitral valve and to improve the diagnostic accuracy of concomitant congenital heart abnormalities.

Adultmedicine.medical_specialtyHeart malformationDiagnostic accuracy030204 cardiovascular system & hematologyHeart Septal Defects AtrialPosterior mitral valve leaflet03 medical and health sciences0302 clinical medicineMitral valveInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseases030212 general & internal medicineMitral regurgitationMitral Valve Prolapsebusiness.industryMitral Valve InsufficiencyMiddle Agedmedicine.diseaseHypoplasiaShuntingmedicine.anatomical_structurecardiovascular systemCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealEchocardiography (Mount Kisco, N.Y.)REFERENCES
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Laparoscopic Splenectomy for Secondary Cytoreduction in Ovarian Cancer Patients With Localized Spleen Recurrence: Feasibility and Technique

2016

Abstract Study Objective To investigate the feasibility of laparoscopic splenectomy in patients with recurrent ovarian cancer with isolated spleen metastasis. Design (Canadian Task Force classification III). Setting Tertiary referral centre in Rome, Italy. Patients Eight women with an isolated platinum-sensitive splenic relapse of ovarian cancer. Intervention Between February 2013 and May 2015, 8 women with an isolated platinum-sensitive splenic relapse of ovarian cancer were submitted to laparoscopic splenectomy. Measurements and Main Results All patients underwent laparoscopic splenectomy without conversion to an open approach. The median estimated intraoperative blood loss was 100 mL (ra…

Adultmedicine.medical_specialtyIntraoperative ComplicationSettore MED/18 - CHIRURGIA GENERALEmedicine.medical_treatmentOperative TimeSplenectomySpleenLaparoscopic splenectomy03 medical and health sciences0302 clinical medicineObstetrics and gynaecologymedicineHumansLaparoscopyAgedOvarian Neoplasms030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industrySplenic NeoplasmsObstetrics and GynecologyCytoreduction Surgical ProceduresLength of StayMiddle Agedmedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureItalyChemotherapy AdjuvantRecurrent Ovarian Cancer030220 oncology & carcinogenesisSplenectomyFeasibility StudiesFemaleLaparoscopyRecurrent ovarian cancerNeoplasm Recurrence LocalbusinessOvarian cancerFollow-Up StudiesJournal of Minimally Invasive Gynecology
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Hysteroscopic Isthmoplasty: Step-by-Step Technique

2018

Study Objective To demonstrate our technique for surgical hysteroscopy performed with a standard-size resectoscope or miniresectoscope in 3 cases of isthmocele. Design Step-by-step demonstration of the technique using slides, pictures, and video (educative video) (Canadian Task Force classification III). Setting Isthmocele is a characteristic semidiverticular anomaly of the anterior isthmic wall of the uterus, located at the site of a previous cesarean delivery scar. The etiopathogenesis of isthmocele remains poorly understood, although several hypotheses have been proposed. Factors that may possibly play a role in niche development include a very low incision through cervical tissue, inade…

Adultmedicine.medical_specialtyIsthmocelemedicine.medical_treatmentUterusAdhesion (medicine)Hysteroscopy03 medical and health sciencesCicatrix0302 clinical medicineObstetrics and gynaecologyPregnancymedicineHumansLaparoscopyUterine DiseasesIsthmoplasty030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryCesarean SectionPelvic painUterusObstetrics and Gynecologymedicine.diseaseAblationHysteroscopic resectionSurgerymedicine.anatomical_structureTreatment OutcomeHysteroscopy030220 oncology & carcinogenesisFemalemedicine.symptomPouchbusiness
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Robotic Radical Hysterectomy After Concomitant Chemoradiation in Locally Advanced Cervical Cancer: A Prospective Phase II Study

2016

Study Objective To assess the feasibility of total robotic radical surgery (TRRS) in patients with locally advanced cervical cancer (LACC) who receive chemoradiation therapy (CT/RT). Design A prospective (preplanned) study of a nonrandomized controlled trial (Canadian Task Force classification level 2). Setting Catholic University of the Sacred Hearth, Rome, Italy. Patients Between September 2013 and January 2016, a total of 40 patients with LACC (Fédération Internationale de Gynécologie et d'Obstétrique stage IB2–III) were enrolled in the study. Interventions Robotic radical hysterectomy (RRH) plus pelvic and/or aortic lymphadenectomy was attempted within 6 weeks after CT/RT. The feasibili…

Adultmedicine.medical_specialtyLocally advancedPhases of clinical researchUterine Cervical NeoplasmsChemoradiation; Locally advanced cervical cancer; Robotic radical hysterectomyHysterectomy03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRobotic Surgical ProceduresRobotic radical hysterectomymedicineHumansIn patientRadical surgeryRadical HysterectomyChemoradiation; Locally advanced cervical cancer; Robotic radical hysterectomy; Obstetrics and GynecologyAgedCervical cancerLocally advanced cervical cancer030219 obstetrics & reproductive medicinebusiness.industryObstetrics and GynecologyChemoradiotherapy AdjuvantMiddle Agedmedicine.diseaseCombined Modality TherapySurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAChemoradiation030220 oncology & carcinogenesisConcomitantCarcinoma Squamous CellDisease ProgressionFeasibility StudiesLymph Node ExcisionFemaleLaparoscopybusiness
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Surgical Neuropelviology: Combined Sacral Plexus Neurolysis and Laparoscopic Laterally Extended Endopelvic Resection in Deep Lateral Pelvic Endometri…

2020

ABSTRACT Objective Surgical demonstration of combined sacral plexus neurolysis and laparoscopic laterally extended endopelvic resection for deep lateral infiltrating endometriosis. Design Video showing principles of neurolysis and laparoscopic laterally extended endopelvic resection applied to endometriotic surgery. Setting University tertiary referral center. Deep infiltrating endometriosis is an underestimated disease with real medical and clinical issues, recently classified as central pelvic endometriosis and lateral pelvic endometriosis further divided into superficial and deep according to the structures’ involvement [1] . The surgical removal of endometriotic foci remains the standar…

Adultmedicine.medical_specialtyNeuronavigationLumbosacral PlexusEndometriosisEndometriosisCystectomyComplete resectionLaparoscopic-assisted neuronavigationPelvisResection03 medical and health sciences0302 clinical medicinemedicineHumansEndometriosiNeurolysisPelvic side wall030219 obstetrics & reproductive medicinePelvic endometriosisbusiness.industryStandard treatmentObstetrics and Gynecologymedicine.diseaseSacral plexusSurgeryNeuroanatomy030220 oncology & carcinogenesisL-LEERFemaleLaparoscopybusinessLumbosacral Plexu
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Robotic Total Mesometrial Resection versus Laparoscopic Total Mesometrial Resection in Early Cervical Cancer: A Case-Control Study

2016

Abstract Study Objective To report our experience with robotic total mesometrial resection (R-TMMR) comparing perioperative results with a series of laparoscopic total mesometrial resections (L-TMMRs). Design Multicenter retrospective case-control study (Canadian Task Force classification II-2). Setting Catholic University of the Sacred Heart of Rome (Italy) and Campobasso (Italy). Patients From July 2013 to August 2015 all cervical cancer patients with preoperative FIGO stage IA2 to IB1 were assessed at preoperative magnetic resonance imaging scan and clinically confirmed by investigation under anesthesia, complying strictly with the FIGO criteria. Surgical and postsurgical data of the TMM…

Adultmedicine.medical_specialtyOperative TimeUterine Cervical Neoplasms03 medical and health sciences0302 clinical medicineRobotic Surgical ProceduresObstetrics and gynaecologymedicineHumansRobotic surgeryStage (cooking)LaparoscopyAgedRetrospective StudiesCervical cancerTotal mesometrial resection (TMMR)030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryObstetrics and GynecologyRobotic Surgical ProceduresRobotic surgeryRetrospective cohort studyPerioperativeMiddle Agedmedicine.diseaseSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAItalyCase-Control Studies030220 oncology & carcinogenesisCervical cancerFemaleLaparoscopyCervical cancer; Laparoscopy; Robotic surgery; Total mesometrial resection (TMMR)businessCervical cancer; Laparoscopy; Robotic surgery; Total mesometrial resection (TMMR); Obstetrics and GynecologyJournal of Minimally Invasive Gynecology
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Uterine leiomyoma metastasis as a first sign of breast cancer

1998

Uterine metastases from extragenital cancer are rarely reported in the literature. More frequently, the female genital tract is involved by direct extension from an adjacent pelvic organ. A 37-year-old woman had a myoma of the uterine wall and hypermenorrhea. The mass was laparoscopically enucleated, and frozen section examination was performed because it was macroscopically suspicious for sarcomatoid degeneration. The final diagnosis was metastatic carcinoma in the uterus of probable breast origin.

Adultmedicine.medical_specialtyPathologyUterusAntineoplastic AgentsBreast NeoplasmsMetastatic carcinomaMetastasisFatal OutcomeBreast cancermedicineHumansGynecologyFrozen section procedureUterine leiomyomaLeiomyomabusiness.industryBiopsy NeedleObstetrics and GynecologyCancerMyomamedicine.diseaseImmunohistochemistrymedicine.anatomical_structureChemotherapy AdjuvantLymphatic MetastasisUterine NeoplasmsFemaleLaparoscopyRadiotherapy AdjuvantbusinessThe Journal of the American Association of Gynecologic Laparoscopists
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Clinical effectiveness of different natalizumab interval dosing schedules in a large Italian population of patients with multiple sclerosis

2020

IntroductionNatalizumab (NTZ) is one of the most effective treatment options for multiple sclerosis (MS) treatment. Our study aimed to evaluate the effectiveness of NTZ when administered according to the extended dosing strategy compared with standard 4-weekly administration in a large Italian MS population.Materials and methodsThis retrospective multicentre study included patients with relapsing-remitting MS (RR-MS) who received NTZ administrations between the 1 June 2012 and the 15 May 2018 and were followed by the ‘Italian MS Register’. All patients with MS were stratified into two groups based on NTZ administration schedule: standard interval dosing (SID) patients who received infusions…

Adultmedicine.medical_specialtyPopulationmultiple sclerosisDrug Administration Schedule03 medical and health sciencesMultiple Sclerosis Relapsing-Remittingnatalizumab0302 clinical medicineNatalizumabDosing schedulesInternal medicinemedicineHumansImmunologic Factorsnatalizumab risk stratification multiple sclerosis safety effectivenessDosingeducationProportional Hazards ModelsRetrospective Studies030304 developmental biology0303 health scienceseducation.field_of_studyProportional hazards modelbusiness.industryMultiple sclerosisRetrospective cohort studyMiddle Agedmedicine.diseasePsychiatry and Mental healthTreatment OutcomeItalyTolerabilitySettore MED/26 - NeurologiaSurgeryNeurology (clinical)business030217 neurology & neurosurgerymedicine.drugJournal of Neurology, Neurosurgery & Psychiatry
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A laparoscopic risk-adjusted model to predict major complications after primary debulking surgery in ovarian cancer: A single-institution assessment

2016

Abstract Objective To develop and validate a simple adjusted laparoscopic score to predict major postoperative complications after primary debulking surgery (PDS) in advanced epithelial ovarian cancer (AEOC). Methods From January 2006 to June 2015, preoperative, intraoperative, and post-operative outcome data from patients undergoing staging laparoscopy (S-LPS) before receiving PDS (n=555) were prospectively collected in an electronic database and retrospectively analyzed. Major complications were defined as levels 3 to 5 of MSKCC classification. On the basis of a multivariate regression model, the score was developed using a random two-thirds of the population (n=370) and was validated on …

Adultmedicine.medical_specialtyPost-operative complicationsPopulationLaparoscopy; Ovarian cancer; Post-operative complications; Predictive model; Obstetrics and Gynecology; OncologyRisk AssessmentYoung Adult03 medical and health sciencesGynecologic Surgical ProceduresPostoperative Complications0302 clinical medicineOvarian cancerAscitesHumansMedicineMajor complicationLaparoscopy; Ovarian cancer; Post-operative complications; Predictive modelYoung adultLaparoscopyeducationAgedAged 80 and overOvarian Neoplasmseducation.field_of_studyModels Statistical030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryReproducibility of ResultsObstetrics and GynecologyMiddle Agedmedicine.diseaseDebulkingSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAItalyOncologyPredictive model030220 oncology & carcinogenesisFemaleLaparoscopymedicine.symptombusinessOvarian cancerRisk assessment
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Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective coho…

2012

Objective To quantify the effect on reproductive outcome of culturing and selecting embryos using a novel time-lapse monitoring system (TMS). Design Retrospective observational cohort study. Setting University-affiliated private center. Patient(s) Donation and autologous intracytoplasmic sperm injection (ICSI) cycles from ten IVF clinics using similar procedures, cultured in TMS (n = 1,390) or in a standard incubator (SI; n=5,915). Intervention(s) None. Main Outcome Measure(s) Clinical pregnancy rate confirmed by ultrasound in week 7. Result(s) A logistic regression analysis, which included all significant confounding factors, was used to evaluate the effect of culturing and selecting embry…

Adultmedicine.medical_specialtyPregnancy Ratemedicine.medical_treatmentFertilization in VitroTime-Lapse ImagingIntracytoplasmic sperm injectionIncubatorsYoung AdultPregnancymedicinePrevalenceHumansGynecologyPregnancybusiness.industryConfoundingObstetrics and GynecologyFertility PreservationRetrospective cohort studyOdds ratioMiddle Agedmedicine.diseaseEmbryo TransferEmbryo transferPregnancy rateTreatment OutcomeReproductive MedicineSpainFemalebusinessCohort studyFertility and sterility
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