Search results for "LDH"
showing 10 items of 1015 documents
The relationship between animal cruelty in children and adolescent and interpersonal violence: A systematic review
2019
Abstract The following study is a systematic review of the relationship between animal cruelty and interpersonal violence. The systematic literature review following PRISMA guidelines and combined with the application of inclusion and exclusion criteria, enabled us to locate 32 studies published between 1995 and July 2017. Overall, the results show that episodes of animal cruelty during childhood and adolescence tend to co-occur alongside other forms of violent and antisocial behaviors. Cruelty to animals was associated with bullying, behavioral problems, experiences of abuse (emotional, physical and sexual), and juvenile delinquency. Furthermore, recurrent animal cruelty during childhood a…
Decreased serum granulysin levels in childhood tuberculosis which reverse after therapy
2007
Abstract Granulysin is a cytolytic protein of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). Serum levels of granulysin are related to host cellular immunity. We used an ELISA to quantify granulysin serum levels in children with tuberculosis (TB), before and after chemotherapy. The study involved children affected by different clinical forms of TB (n=72) and healthy control children (n=150) from the same geographical area and of similar socio-economic background. Serum granulysin levels before the initiation of TB therapy were significantly lower in children with TB compared to controls, with the lowest levels being found in TB patients who were PPD skin test negative. No sta…
A specific microassay for evaluating hepatic LDH activity in co-cultures of hepatocytes with other cells.
1994
This study describes the development of a simple, rapid and reproducible microassay for determining the intracellular LDH activity of rat hepatocytes present in a co-culture system with other cells. The procedure involves treatment of cellular homogenates with an anti-LDH antiserum that specifically inhibits the LDH activity of rat hepatocytes. The assay is performed in 96-well plates and LDH activity can be measured directly in the same wells using a colorimetric method. The difference in LDH activity values measured before and after antiserum incubation reflects the LDH content of the hepatocytes in the sample. The advantages of this method are the small number of cells required, a reduct…
Autobiographical memory for the differential diagnosis of cognitive pathology in aging
2015
Aim The present study distinguishes three memory stages across the lifespan, and aims to compare episodic and semantic autobiographical memory in healthy older adults, with amnesic mild cognitive impairment, and with Alzheimer's disease. This information can offer evidence about the way semantic and episodic autobiographical memory work, and how the disease affects them. Methods The sample was composed of 56 people, all aged over 60 years; 15 with amnestic mild cognitive impairment, 12 with Alzheimer's disease and 29 healthy older people. Participants were evaluated with the Autobiographical Memory Interview. Results A mixed anova showed significant main effects of memory and time-period, a…
Entre la equidad y la conciliación: similitudes y disparidades en el diseño institucional del primer ciclo de educación infantil en España
2022
Versión en castellano e inglés La provisión del primer ciclo de educación infantil (EI a partir de ahora) ha aumentado de manera sostenida en España desde el año 2000. A pesar de una considerable dispersión territorial, esta expansión ha tenido lugar en todas las comunidades autónomas (CC. AA.). En este artículo estudiamos cómo los distintos diseños institucionales a escala autonómica impactan en la equidad tanto en el acceso al servicio como en el coste para las familias. Tratamos de averiguar en qué condiciones puede el primer ciclo de EI ir más allá de una política de conciliación empleo/familia y considerarse una política redistributiva y de igualdad de oportunidades que favorezca acced…
Learning and behaviour of three- to five-year-old children with ADHD / Aprendizaje y conducta de niños y niñas con TDAH de tres a cinco años
2015
AbstractEarly childhood education is a developmental period in which early symptoms of attention deficit hyperactivity disorder (ADHD) can be observed. This work examines the educational background of 206 children, from the ages of three to five years (109 of them with an ADHD diagnosis and 97 without a clinical diagnosis), by analysing 306 reports from their teachers. The aim of this study is to discover if these educational reports reflect differences in academic performance and behaviour between both groups. The 123 educational goals analysed in the reports have been classified into 15 categories. A nonparametric analysis (Chi square) was performed on each variable to compare ADHD/contro…
Postnatal overfeeding in rats leads to moderate overweight and to cardiometabolic and oxidative alterations in adulthood.
2011
In contrast to the masses of data on obesity, few data are available concerning the cardiometabolic and oxidative consequences of moderate overweight. The model of postnatal overfeeding (OF) induces an increase in body weight at weaning that remains during adult life. Litters of Wistar rats were either maintained at 12 pups (normal-fed group, NF), or reduced to 3 pups at birth in order to induce OF. At 6 months of age, metabolic parameters, circulating oxidative stress and aortic and coronary vasoreactivity were assessed. Cardiac susceptibility to ischemia-reperfusion injury was also evaluated ex vivo as were markers of cardiac remodeling. OF led to an increase in body weight at weaning (+5…
Physical Inactivity from Youth to Adulthood and Risk of Impaired Glucose Metabolism
2018
Introduction: Physical activity (PA) is important in the prevention and treatment of impaired glucose metabolism. However, association of physical inactivity during the transition between childhood and adulthood with glucose metabolism is unknown. Therefore, we studied the association of persistent physical inactivity since childhood with glucose metabolism in adulthood. Methods: Data were drawn from the ongoing, Cardiovascular Risk in Young Finns Study with repeated follow-ups between 1980 and 2011 (baseline age, 3-18 yr; n = 3596). Impaired glucose metabolism was defined as having impaired fasting glucose (6.1-6.9 mmol·L-1) or type 2 diabetes in adulthood. Leisure-time PA habits were repe…
The impact of maternal weight in pregnancy on glucose metabolism in non-diabetic offspring in late adulthood
2019
Aims: We aimed to examine the association between maternal adiposity and glucose metabolism in adult offspring without diabetes, simultaneous taking offspring own adiposity into account. Methods: This longitudinal birth cohort study (Helsinki Birth Cohort Study) included 1,440 non-diabetic subjects examined at a mean age of 62 years. Subjects were divided into quartiles according to maternal body mass index (BMI). The impact of maternal BMI on offspring body composition was also studied. Results: There were no differences in fasting glucose between the groups. In men, maternal BMI was inversely associated with mean 2-hour glucose concentration after a 75 g oral glucose tolerance test (p <0.…
Relationship between childhood obesity cut-offs and metabolic and vascular comorbidities: comparative analysis of three growth standards
2013
Background: To compare the association between metabolic and vascular comorbidities and the body mass (BMI)-for-age cut-off criteria from three growth standards [Centers for Disease Control and Prevention (CDC), 2000; World Health Organization (WHO), 2007; Spanish Reference Criteria (Carrascosa Lezcano et al., 2008)] that are used to define being overweight and obese in childhood. Methods: A prospective study was conducted in 137 children (aged 8–16 years). Based on BMI-for-age Z-scores according to WHO cut-offs, 59 participants were obese, 35 were overweight and 43 were normal-weight. All participating children were subsequently reclassified applying the CDC and Spanish Reference Criteria.…