Search results for "LDL"

Relazione tra il size delle LDL e l’estensione della malattia vasale coronarica in 72 pazienti maschi sottoposti a coronarografia diagnostica

2005

LDL peak particle size and the extension of coronary atherosclerosis in 72 patients that underwent an angiographic exam

2004

LDL size, density and receptor affinity variation during an oral load in mild hyper-triglyceridemic and normal subjects

2003

A metallothionein family member interacts with the intracellular domain of the low density lipoprotein (ldl) receptor.

2007

Lipid-lowering therapies and achievement of LDL-cholesterol targets.

2012

Low-density-lipoprotein peak particle size in a Mediterranean population.

2003

Background: The predominance of small, dense low-density lipoprotein (LDL) particles ('LDL phenotype B') has been associated with a three-fold increased risk of myocardial infarction, but the feasibility of the identification of small, dense LDL as independent predictors of coronary artery disease risk in population studies remains questioned. Design: We evaluated the LDL peak particle size and its relation with other established risk factors for coronary heart disease in a group of 156 randomized subjects living on the Mediterranean island of Ustica (71 males and 85 women, range of age 20-69 years), representing approximately 30% of the total population. Results: The prevalence of LDL phen…

A NOVEL LOSS OF FUNCTION MUTATION OF PCSK9 GENE

2006

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

2012

BACKGROUND: High plasma HDL cholesterol is associated with reduced risk of myocardial infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are randomly assigned at meiosis, are independent of non-genetic confounding, and are unmodified by disease processes, mendelian randomisation can be used to test the hypothesis that the association of a plasma biomarker with disease is causal. METHODS: We performed two mendelian randomisation analyses. First, we used as an instrument a single nucleotide polymorphism (SNP) in the endothelial lipase gene (LIPG Asn396Ser) and tested this SNP in 20 studies (20,913 myocardial infarction cases, 95,407 controls). Se…

Data from: Plant – herbivorous beetle networks: molecular characterization of trophic ecology within a threatened steppic environment

2015

DNA barcoding facilitates many evolutionary and ecological studies, including the examination of the dietary diversity of herbivores. In this study, we present a survey of ecological associations between herbivorous beetles and host plants from seriously threatened European steppic grasslands. We determined host plants for the majority (65%) of steppic leaf beetles (55 species) and weevils (59) known from central Europe using two barcodes (trnL and rbcL) and two sequencing strategies (Sanger for mono/oligophagous species and Illumina for polyphagous taxa). To better understand the ecological associations between steppic beetles and their host plants, we tested the hypothesis that leaf beetl…

Volatiles in pantellerite magmas: A case study of the Green Tuff Plinian eruption (Island of Pantelleria, Italy)

2013

Abstract The Green Tuff (GT) Plinian eruption, the largest in magnitude at Pantelleria, erupted 3 to 7 km3 DRE of pantellerite magma and a small volume of trachyte. Fifty-nine anorthoclase-hosted melt inclusions from the two basal pumice members were analyzed by FT-IR spectroscopy in order to assess the pre-eruptive H2O content in the pantellerite melt. Microanalytical methods were used to determine major element, Cl, F and S contents. Melt inclusions and glassy groundmasses have a nearly homogeneous pantelleritic composition (peralkaline index = 1.9-2.2) and variable water contents ranging from 1.4 to as high as 4.2 wt %, i.e. much higher than the 1.4 wt % of earlier published studies. The…