Search results for "LED"
showing 10 items of 8768 documents
Resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and uncontrolled haemorrhagic shock: a systematic rev…
2021
AbstractBackgroundMultiple studies regarding the use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in patients with non-compressible torso injuries and uncontrolled haemorrhagic shock were recently published. To date, the clinical evidence of the efficacy of REBOA is still debated. We aimed to conduct a systematic review assessing the clinical efficacy and safety of REBOA in patients with major trauma and uncontrolled haemorrhagic shock.MethodsWe systematically searched MEDLINE (PubMed), EMBASE and CENTRAL up to June 2020. All randomized controlled trials and observational studies that investigated the use of REBOA compared to resuscitative thoracotomy (RT) with/witho…
Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures.
2014
Formation of superstructures in protein aggregation processes has been indicated as a general pathway for several proteins, possibly playing a role in human pathologies. There is a severe lack of knowledge on the origin of such species in terms of both mechanisms of formation and structural features. We use equine lysozyme as a model protein, and by combining spectroscopic techniques and microscopy with X-ray fiber diffraction and ab initio modeling of Small Angle X-ray Scattering data, we isolate the partially unfolded state from which one of these superstructures (i.e., particulate) originates. We reveal the low-resolution structure of the unfolded state and its mechanism of formation, hi…
Pirate John Gow and Literary Renderings of his Career by Daniel Defoe and Sir Walter Scott
2018
This article analyses two literary representations - by Daniel Defoe and Sir Walter Scott - of the career of an early-18th century Orkney pirate in order to confront the contemporary view of John Gow as an unprincipled cutthroat with later literary images of a Romantic corsair. It therefore examines evolving literary approaches in the period to socially transgressive behaviour.
Real-world experience with obeticholic acid in patients with primary biliary cholangitis
2021
Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of OCA under real-world conditions. Methods Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. The primary endpoint was the biochemical response according to Poise criteria; the secondary endpoint was the biochemical response according to normal range criteria, defined as normal levels of bilirubin, alkaline phosphatase (ALP), and alanine aminotransfer…
PROGETTARE L’ADATTAMENTO. Resilienze di agricoltura urbana nel contesto europeo
2022
I crescenti fenomeni legati al cambiamento climatico spingono le città a sviluppare piani di resilienza che possano rispondere in termini di sostenibilità ambientale, sociale ed economica. Le strategie nature-based possono rappresentare una soluzione; tra queste l’agricoltura urbana può contribuire ad aumentare la resilienza dei tessuti urbani europei. Questa attività è stata più volte oggetto di interesse in periodi di crisi come impegno comunitario dai caratteri sociali, oltre che produttivi ed educativi. Attraverso un excursus storico e una successiva analisi di casi studio contemporanei, il paper fornisce strumenti progettuali per intervenire nel costruito con strategie che spaziano dal…
IEA EBC Annex83 Positive Energy Districts
2021
At a global level, the need for energy efficiency and an increased share of renewable energy sources is evident, as is the crucial role of cities due to the rapid urbanization rate. As a consequence of this, the research work related to Positive Energy Districts (PED) has accelerated in recent years. A common shared definition, as well as technological approaches or methodological issues related to PEDs are still unclear in this development and a global scientific discussion is needed. The International Energy Agency’s Energy in Buildings and Communities Programme (IEA EBC) Annex 83 is the main platform for this international scientific debate and research. This paper describes the challeng…
Dual Enzyme-Triggered Controlled Release on Capped Nanometric Silica Mesoporous Supports
2012
The development of nanoscopic hybrid materials equipped with “molecular gates” showing the ability of releasing target entrapped guests upon the application of an external trigger has attracted great attention and has been extensively explored during recent years.1 These nanodevices are composed of two subunits, namely, a suitable support and certain capping entities grafted on the surface of the scaffolding.2 The support is used as a suitable reservoir in which certain chemicals can be stored whereas the molecules grafted in the outer surface act as a “gate” and can control the release of the entrapped molecules at will. Both components are carefully selected and arranged in order to achie…
The Effect of Moderate- Versus High-Intensity Resistance Training on Systemic Redox State and DNA Damage in Healthy Older Women
2018
This study investigated effects of a 16-week progressive resistance training program (RTP) with elastic bands at two different intensities on systemic redox state, DNA damage, and physical function in healthy older women. Methods: Participants were randomly assigned to the high-intensity group (HIGH; n = 39), moderate-intensity group (MOD; n = 31), or control group (CG; n = 23). The exercise groups performed an RTP twice a week with three to four sets of 6 (HIGH) or 15 (MOD) repetitions of six overall body exercises at a perceived exertion rate of 8-9 on the OMNI-Resistance Exercise Scale for use with elastic bands. Thiol redox state was determined by reduced glutathione (GSH), oxidized glu…
La rilevanza degli interessi moratori nel giudizio di usura in astratto
2020
La Sezione I della Cassazione ha rimesso alle Sezioni unite le questioni relative alla rilevanza usuraria degli interessi moratori, alla configurabilità o meno del c.d. principio di simmetria e all’eventuale individuazione di un tasso usura ad hoc per gli interessi moratori. A fronte di tali interrogativi, va rimarcata invece la conformità al sistema della disciplina contro l’usura tanto della rilevanza usuraria degli interessi moratori quanto della necessità della loro valutazione congiunta alle altre voci di remunerazione, di costo o di spesa, cui non osta la mancata inclusione degli interessi moratori all’interno del tasso effettivo globale medio della categoria omogenea di operazioni al…
Interaction between surface plasmon polaritons and molecules in strong coupling limit
2016
Miniaturization of optical elements and their integration to electronic circuits is limited by diffraction limit. It was realized that light being coupled to surface plasmons (SP) can overcome this limit. Employing also optically active molecules in combination with SPs can drive optical circuits to nm-scale and add functionalities. For efficient performance of plasmonic elements involving fluorescent dye molecules investigation of physics behind their interaction is of high priority. In this thesis interaction between surface plasmon polaritons (SPPs) and different dye molecules has been studied, especially within strong coupling limit, which brings in totally new physical properties in th…