Search results for "LEEP"

showing 10 items of 985 documents

Polysomnographic Findings in Fragile X Syndrome Children with EEG Abnormalities

2019

Fragile X syndrome (FXS) is a genetic syndrome with intellectual disability due to the loss of expression of the FMR1 gene located on chromosome X (Xq27.3). This mutation can suppress the fragile X mental retardation protein (FMRP) with an impact on synaptic functioning and neuronal plasticity. Among associated sign and symptoms of this genetic condition, sleep disturbances have been already described, but few polysomnographic reports in pediatric age have been reported. This multicenter case-control study is aimed at assessing the sleep macrostructure and at analyzing the presence of EEG abnormalities in a cohort of FXS children. We enrolled children with FXS and, as controls, children wit…

MaleSleep Wake Disorderscongenital hereditary and neonatal diseases and abnormalitiesPediatricsmedicine.medical_specialtyAdolescentArticle SubjectPolysomnographyNeurosciences. Biological psychiatry. NeuropsychiatryFragile X Mental Retardation Protein03 medical and health sciences0302 clinical medicinechildrenIntellectual disabilitymedicineHumansIctalCircadian rhythmChildEEG abnormalitiesPathologicalPSG030304 developmental biology0303 health sciencesNeuronal PlasticityFragile X syndrome; intellectual disability; polysomnographicbusiness.industryCase-control studyNeuropsychologyElectroencephalographyGeneral Medicinemedicine.diseasepolysomnographicFragile X syndromeNeuropsychology and Physiological PsychologyNeurologyintellectual disabilityCase-Control StudiesFragile X SyndromeCohortFemaleNeurology (clinical)FXSSleepbusiness030217 neurology & neurosurgeryRC321-571Research ArticleBehavioural Neurology
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Bidirectional relationship between caregiver burden and neuropsychiatric symptoms in patients with Alzheimer's disease: A narrative review

2019

Objective: The aim of this review is to make a state of the art of the potential influence of neuropsychiatric symptoms (NPs) on caregiver stress and vice versa. Methods: We searched PubMed and Google Scholar for potential eligible articles. Results: Patients with Alzheimer's disease (AD) usually need high levels of care in all activities of daily living, most of them provided by family members, friends, or informal caregivers. Caregivers have to cope with both age-related conditions and dementia-related factors. Therefore, caregiving in dementia is more difficult and stressful than caregiving for older adults, affected by other conditions. Neuropsychiatric symptoms, such as anxiety, agitat…

MaleSleep Wake Disordersmedicine.medical_specialtyActivities of daily livingHealth StatusDisease03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Cost of IllnessAlzheimer DiseaseRisk Factors030502 gerontologyActivities of Daily LivingAdaptation PsychologicalmedicineHumansDementiaFamilySocial isolationSpousesPsychiatryAgedAged 80 and overcaregiver burdenbusiness.industryMental DisordersCaregiver burdenMiddle AgedAlzheimer's diseasemedicine.diseaseAnxiety DisordersPsychiatry and Mental healthCaregiversSocial IsolationQuality of LifeAnxietyCaregiver stressFemaleneuropsychiatric symptomsGeriatrics and Gerontologymedicine.symptom0305 other medical sciencebusiness030217 neurology & neurosurgery
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Perceived tiredness among adolescents and its association with sleep habits and use of psychoactive substances

1997

This study investigated the variation in perceived tiredness among 11, 13 and 15-year-old Finnish adolescents (n = 4187). Additionally interrelationships between sleep habits, use of psychoactive substances (alcohol, tobacco and coffee) and perceived tiredness among 15-year-olds were examined. This study is part of an international, WHO-coordinated survey of school children's health and lifestyle (the HBSC Study). In Finland, research data represented the whole country. The data were collected in March-May 1994. Pupils responded anonymously to a standardized questionnaire during a class period. Subjective tiredness was very common and increased with age among adolescents. Perceived tirednes…

MaleSleep Wake Disordersmedicine.medical_specialtyAdolescentSubstance-Related DisordersCognitive NeuroscienceStructural equation modelingBehavioral NeuroscienceSex FactorsCaffeineAge relatedTobaccomedicineHumansChildPsychiatryAssociation (psychology)FatigueResearch dataEthanolAge FactorsGeneral MedicineSleep in non-human animalsPlants ToxicHealth promotionAdolescent BehaviorFemaleFeeling tiredPsychologyClinical psychologyJournal of Sleep Research
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Sleep Quality in Patients with Heart Failure in the Spanish Population: A Cross-Sectional Study

2020

Background: Heart failure is a major problem in western societies. Sleep Disorders maintain a bidirectional relationship with heart failure, as shown by studies conducted in other countries. This study aims to describe the quality of sleep in Spanish patients with heart failure. Materials and methods: We carried out a cross-sectional study to analyze the quality of sleep in a sample of 203 patients with a diagnosis of heart failure admitted to an Internal Medicine Service. The Pittsburg Sleep Quality Index (PSQI) was used to evaluate sleep quality in our sample over a one-month period. Results: 75% of the sample presented sleep disorders. The most common problems included the interruption o…

MaleSleep Wake Disordersmedicine.medical_specialtyCross-sectional studyHealth Toxicology and Mutagenesisheart failurelcsh:Medicine030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesMedicineNocturiaHumans030212 general & internal medicineAgedsleep disorderAged 80 and overSleep disorderSleep qualitybusiness.industryBrief Reportlcsh:RPublic Health Environmental and Occupational Healthsleep qualitymedicine.diseaseSleep in non-human animalsSpanish populationCross-Sectional StudiesSpainHeart failureEmergency medicineBreathingFemaleheart failure sleep disorder sleep qualitymedicine.symptombusinessSleepInternational Journal of Environmental Research and Public Health
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Comment on “Sleep disturbances and later cognitive status: a multi-centre study”

2018

To investigate the associations between sleep disturbances in mid-life and late-life and late-life cognitive status.In four population-based studies (three Swedish studies: H70 study, Kungsholmen Project (KP) and The Swedish Panel Study of Living Conditions of the Oldest Old (SWEOLD); and one Finnish study: Cardiovascular Risk Factors, Aging and Dementia (CAIDE)), participants provided self-reports on insomnia, nightmares and general sleep problems. Late-life cognitive status was measured by the Mini Mental State Exam (MMSE). The associations between late-life sleep disturbances and cognition 3-11 years later were investigated across all studies (n = 3210). Mean baseline ages were 70 (CAIDE…

MaleSleep Wake Disordersmedicine.medical_specialtyDisease03 medical and health sciencesCognition0302 clinical medicinePhysical medicine and rehabilitationRisk FactorsSleep Initiation and Maintenance DisordersHumansMedicineDementiaCircadian rhythmRisk factorFinlandAgedSlow-wave sleepAged 80 and overSweden030214 geriatricsbusiness.industryEye movementSleep disturbancesGeneral MedicineMental Status and Dementia Testsmedicine.diseaseSleep in non-human animalsEditorialCognitive impairmentAgeingFemaleSettore MED/26 - NeurologiaSelf Reportbusiness030217 neurology & neurosurgeryAnnals of Translational Medicine
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Modified 2016 American College of Rheumatology Fibromyalgia Criteria, the Analgesic, Anesthetic, and Addiction Clinical Trial Translations Innovation…

2021

Objective To study the prevalence of fibromyalgia (FM) in the general population according to a 2016 modification of the American College of Rheumatology criteria (FM 2016) and the Analgesic, Anesthetic, and Addiction Clinical Trial Translations Innovations Opportunities and Networks-American Pain Society pain taxonomy criteria (AAPT), and to compare diagnostic and clinical variables between the criteria sets. Methods We studied 2,531 randomly selected subjects from the German general population in 2019. Pain regions from the Michigan Body Map were fitted to the FM 2016 and the AAPT criteria, and criteria symptom items were derived from validated questionnaires assessing somatic and psychol…

MaleSleep Wake Disordersmedicine.medical_specialtyFibromyalgiaCross-sectional studyPopulationPainSeverity of Illness IndexRheumatologyPredictive Value of TestsGermanySurveys and QuestionnairesFibromyalgiaSeverity of illnessPrevalencemedicineHumanseducationFatigueeducation.field_of_studybusiness.industryMiddle Agedmedicine.diseaseConfidence intervalClinical trialDistressCross-Sectional StudiesPredictive value of testsPhysical therapyFemalebusinessArthritis Care & Research
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The effects of transdermal rotigotine on non-motor symptoms of Parkinson's disease: a multicentre, observational, retrospective, post-marketing study

2017

This study evaluated the effect of ≥6 months of transdermal rotigotine on non-motor and motor symptoms of patients with advanced Parkinson's disease.The study was conducted in Spain between September 2011 and December 2012 (ClinicalTrials.gov: NCT01504529). The primary efficacy variable was the change from baseline in non-motor symptoms, as assessed by changes in Parkinson's Disease Non-Motor Symptoms Questionnaire total scores at 6 months. Secondary endpoints included the assessment of motor symptoms by Unified Parkinson's Disease Rating Scale III scores.Data from 378 patients (mean age: 70.2 years; 56.9% male) with Parkinson's disease receiving rotigotine from were collected. Mean disease…

MaleSleep Wake Disordersmedicine.medical_specialtyParkinson's diseaseTetrahydronaphthalenesThiophenesDiseaseAdministration CutaneousMotor symptoms03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesProduct Surveillance PostmarketingmedicineHumans030212 general & internal medicineAgedRetrospective StudiesTransdermalAged 80 and overbusiness.industryGeneral NeuroscienceParkinson DiseaseRotigotineGeneral MedicineUrination Disordersmedicine.diseaseClinical PracticeTreatment OutcomeSpainDopamine AgonistsPhysical therapyNon motorFemaleObservational studyCognition Disordersbusiness030217 neurology & neurosurgerymedicine.drugInternational Journal of Neuroscience
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Effects of dental implant treatment on sleep quality in edentulous older people: A prospective cohort study

2020

Background Edentulism and sleep disturbances are commonly seen among older people and cause serious negative effects on their daily lives. Edentulism can induce sleep problems by changing maxillo-mandibular anatomy and surrounding soft tissues. The effect of the treatment of complete edentulism on sleep disturbances is not sufficiently understood. The purpose of this cohort study is to detect how different treatment options affect sleep quality, daytime fatigue and sleep disorder breathing in totally edentulous elderly people. Material and Methods Ninety-six individulas (50 male and 46 female) participated in this prospective cohort study. The patients were non-randomly assigned to three gr…

MaleSleep Wake Disordersmedicine.medical_specialtymedicine.medical_treatmentpolymorphismlaw.inventionCohort StudiesPittsburgh Sleep Quality IndexRandomized controlled triallawSurveys and QuestionnairesHumansMedicineProspective StudiesProspective cohort studyDental implantGeneral DentistryUNESCO:CIENCIAS MÉDICASAgedAged 80 and overDental ImplantsEdentulismSleep qualitybusiness.industryResearchEpworth Sleepiness Scaleoral cancermetallothioneinmedicine.diseaseoral squamous cell carcinomaOtorhinolaryngologyPhysical therapyFemaleSurgerySleepbusinessImplantologyCohort studyMedicina Oral Patología Oral y Cirugia Bucal
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Sleep and alertness in shift work disorder: findings of a field study

2018

Purpose Although shift work disorder (SWD) affects a major part of the shift working population, little is known about its manifestation in real life. This observational field study aimed to provide a detailed picture of sleep and alertness among shift workers with a questionnaire-based SWD, by comparing them to shift workers without SWD during work shifts and free time. Methods SWD was determined by a questionnaire. Questionnaires and 3-week field monitoring, including sleep diaries, actigraphy, the Karolinska Sleepiness Scale (KSS), EEG-based sleep recordings, and Psychomotor Vigilance Tasks (PVT), were used to study 22 SWD cases and 9 non-SWD workers. Results The SWD group had a shorter …

MaleSleepinessSTRESSShift workSCHEDULESväsymysAudiologyunettomuusShift work0302 clinical medicineSleep debtSurveys and QuestionnairesWork Schedule ToleranceCircadian rhythm disordersInsomniaMedicineAttention030212 general & internal medicinePREDICTORSFinlandvuorokausirytmimedia_commonElectroencephalographyMiddle AgedRECOVERY030210 environmental & occupational healthvuorotyöOriginal ArticleFemaleSleep diaryHEALTHmedicine.symptomVigilance (psychology)Adultmedicine.medical_specialtyInsomnia515 PsychologySleep diarymedia_common.quotation_subjectsleepinessBedtime03 medical and health sciencesLeisure ActivitiesSleep Disorders Circadian RhythmHumansTOLERANCEcircadian rhythm disorderssleep diarybusiness.industryPublic Health Environmental and Occupational HealthActigraphyPERFORMANCEActigraphyAlertnessMOODNURSESAviationSleepbusinessPsychomotor PerformanceInternational Archives of Occupational and Environmental Health
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Sleep and sleepiness in shift-working tram drivers

2020

Driver sleepiness contributes to traffic accidents. However, sleepiness in urban public transport remains an understudied subject. To fill this gap, we examined the sleepiness, sleep, and on-duty sleepiness countermeasures (SCMs) in 23 tram drivers working morning, day, and evening shifts for three weeks. Sleepiness was measured using Karolinska Sleepiness Scale (KSS). Nocturnal total sleep time (TST) was measured with wrist actigraphy. SCMs and naps were self-reported with a smartphone application. Caffeine and napping were considered effective SCMs. Severe sleepiness (KSS >= 7) was observed in 22% of shifts with no differences between shift types. Rest breaks were associated with slight r…

MaleSleepinessTime FactorsväsymysTransportationAudiologySmartphone applicationFATIGUEunettomuusROAD0302 clinical medicineWork Schedule Tolerance11. SustainabilityMedicineSafety Risk Reliability and Quality050107 human factorsSleep lossMorningRISKkuljettajatraitiovaununkuljettajatREST05 social sciencesAccidents TrafficHAULMiddle Aged030210 environmental & occupational health3142 Public health care science environmental and occupational healthvuorotyöFemaleSleep (system call)Sleep lossAdultAutomobile DrivingCAFFEINEmedicine.medical_specialtyEvening515 Psychologyurban transportationPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsINDIVIDUAL-DIFFERENCESsleep lossuni (lepotila)03 medical and health sciencesSleep Disorders Circadian RhythmCOUNTERMEASURESHumans0501 psychology and cognitive sciencesdriver fatigueEngineering (miscellaneous)unihäiriötbusiness.industryUrban transportationActigraphySleep timeDriver fatigueUrban transportationkaupunkiliikenneliikenneonnettomuudetSleepbusiness
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