Search results for "LEEP"

Effect of rapid maxillary expansion on sleep apnea-hypopnea syndrome in growing patients. A meta-analysis.

2019

Background Changes produced in the upper airway after rapid maxillary expansion makes this procedure a therapeutic option for treating sleep apnea-hypopnea syndrome (SAHS) in children. The objective of this systematic review and meta-analysis was to analyze the evidence available for the effects of rapid maxillary expansion (RME) on SAHS, analyzing changes produced in oximetric variables: apnea-hypopnea index (AHI); oxygen saturation (SO2); sleep efficiency (SE), total sleep time (TST), percentage of rapid eye movement (REM) phase; and arousal index (AI). Material and Methods An electronic search was conducted in the PubMed, Scopus, Embase, and Cochrane databases, and in grey literature (Op…

Signal processing procedures for the evaluation of the cardiovascular effects in the obstructive sleep apnea syndrome

2002

A new index, the cross-power index (CPI), is proposed to quantify the severity of obstructive sleep apnea syndrome (OSAS) in terms of its cardiovascular effects. On the basis of the influences that recurring drops in oxygen saturation have on systolic blood pressure variability of OSAS patients, CPI is defined as the integral of the cross-spectrum modulus between systolic blood pressure and oxygen saturation. In a test group of 22 subjects, CPI correctly identified all 15 OSAS patients included in the pool. Moreover, evaluation of CPI in six OSAS patients sleeping with and without a CPAP (continuous positive airway pressure) device demonstrated that CPAP treatment substantially reduced the …

2021

Autoimmune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening, relapsing disease in which an acquired deficiency of the enzyme ADAMTS13 leads to generalised microvascular thrombosis. Survivors have a high prevalence of depression and impaired cognitive function. The aim of this study was to determine whether life circumstances and personality have an influence on the development and severity of depression and anxiety in iTTP patients and how they impact the quality of life. With validated questionnaires, we examined the prevalence of depression and anxiety symptoms in 104 iTTP patients, as well as parameters of subjective cognitive deficits, quality of life, attitude to life a…

Sedation in allergic rhinitis is caused by the condition and not by antihistamine treatment

1996

Sedation is regarded as a common side-effect of most H1-antihistamines. This view must be accepted, yet can hardly be assessed under treatment of allergic disorders. Since central sedative potency is hard to evaluate, different methods of measurement have been introduced in the four phases of clinical investigation. While tests of high complexity in early trials can detect true central effects, they seem to have the disadvantage of not taking into consideration the important interactions of drugs with the disorder. Therefore, we used a visual analog scale (VAS) as an instrument to demonstrate sedative effects in five clinical studies carried out between 1989 and 1994 with a total number of …

Effectiveness of mandibular advancement appliances in treating obstructive sleep apnea syndrome: A systematic review

2015

Objectives/Hypothesis Mandibular advancement devices are an alternative to continuous positive airway pressure for patients with mild or moderate obstructive sleep apnea/hypopnea syndrome (OSAHS). The main aim of this review was to assess the effectiveness of different devices in treating OSAHS, based on polysomnographic measurements such as the apnea/hypopnea index (AHI) and oxygen saturation, and on changes in the upper airway and improvements in the most common symptoms: snoring and somnolence. Their adverse effects were also noted. Study Design Systematic review. Methods Following an exhaustive search in the Medline, Scopus, and Cochrane Library databases, 22 articles published in the p…

Measurement of Pharyngeal Pressure in Patients using Nasal CPAP

1995

In patients with obstructive sleep apnea syndrome (OSAS), nasal continuous positive airway pressure (nCPAP) prevents pharyngeal collapse by applying positive pressure transnasally. Currently there are not objective criteria to determine whether surgical improvement of nasal resistance is necessary in patients undergoing nCPAP treatment. In 16 patients with documented OSAS, inspiratory and expiratory pressures in the pharynx were measured during nCPAP with pressures ranging from 5 to 20 mbar. Identical studies were performed in 12 patients with severe nasal obstruction without OSAS and in eight normal patients. The results of each group were compared to the nasal resistance as measured by a…

Long-term positive airway pressure therapy is associated with reduced total cholesterol levels in patients with obstructive sleep apnea : data from t…

2020

Background and aim: Obstructive sleep apnea (OSA) is an independent risk factor for dyslipidemia. The current study examined the effects of positive airway pressure (PAP) treatment on lipid status in the European Sleep Apnea Database (ESADA). Methods: The prospective cohort study enrolled 1564 OSA subjects (74% male, mean age 54 ± 11y, body mass index (BMI) 32.7 ± 6.6 kg/m2 and apnea-hypopnea index (AHI) 40.3 ± 24.4 n/h) undergoing PAP therapy for at least three months (mean 377.6 ± 419.5 days). Baseline and follow-up total cholesterol (TC) from nine centers were analyzed. Repeated measures and logistic regression tests (adjusted for age, sex, weight changes, lipid lowering medication, PAP …

Evolution of Pediatric Migraine Patients Admitted at an Emergency Department after a 10-Year Follow-Up

2023

Background: Despite its high prevalence, the clinical course of pediatric migraine has not been fully understood, and previous studies present conflicting results. We present here the findings of a 10-year follow-up study involving children with severe migraine pain admitted to our emergency department. Furthermore, all studies were carried out on selected outpatient clinical case studies. Our aim was to evaluate a population of migraine children admitted to an emergency department because of increased severity or frequency of pain or even because of very anxious parents concerning their child’s headache in order to describe their long-term outcomes, whether it differed from that of o…

Nature exposure is not associated with parent-reported or objectively measured sleep quality in 6-year-old children : a study in Finland

2023

Exposure to green environments has been associated with better sleep quality in adults. This study examined whether nature exposure is associated with parent-reported or actigraphy measured sleep quality in children. Against the hypotheses, no differences in sleep quality between the case and control groups or a moderating effect of socioeconomic status or sex were found. Green environment exposure may not serve as an environmental intervention to increase sleep quality in children. peerReviewed

Cluster Analysis of Home Polygraphic Recordings in Symptomatic Habitually-Snoring Children: A Precision Medicine Perspective

2022

(1) Background: Sleep-disordered breathing (SDB) is a frequent problem in children. Cluster analyses offer the possibility of identifying homogeneous groups within a large clinical database. The application of cluster analysis to anthropometric and polysomnographic measures in snoring children would enable the detection of distinctive clinically-relevant phenotypes; (2) Methods: We retrospectively collected the results of nocturnal home-based cardiorespiratory polygraphic recordings and anthropometric measurements in 326 habitually-snoring otherwise healthy children. K-medoids clustering was applied to standardized respiratory and anthropometric measures, followed by Silhouette-based statis…