Search results for "LEEP"

Aplicación de la clasificación de San Diego en el estudio médico-legal de la Muerte Súbita del Lactante

2020

INTRODUCCIÓN La Muerte Súbita del Lactante (MSL) representa un problema universal y grave. El Síndrome de Muerte Súbita del Lactante (SMSL) es la primera causa de muerte en lactantes durante el primer año de vida en países desarrollados y se define como la muerte súbita e inesperada de un lactante, que ocurre durante el sueño y permanece inexplicada tras la realización de una completa investigación postmortem (autopsia con análisis complementarios, examen del lugar de la muerte y revisión de la historia clínica). De esta definición se desprende la clasificación de San Diego basada en las categorías IA, IB y II. Tiene una patogénesis compleja y heterogénea, siendo la teoría del triple riesgo…

Effects of overnight military training and acute battle stress on the cognitive performance of soldiers in simulated urban combat

2022

Understanding the effect of stress, fatigue, and sleep deprivation on the ability to maintain an alert and attentive state in an ecologically valid setting is of importance as lapsing attention can, in many safety-critical professions, have devastating consequences. Here we studied the effect of close-quarters battle (CQ battle) exercise combined with overnight military training with sleep deprivation on cognitive performance, namely sustained attention and response inhibition. In addition, the effect of the CQ battle and overnight training on cardiac activity [heart rate and root mean square of the successive differences (RMSSD)] during the cognitive testing and the relationship between ca…

Physiological and autonomic stress responses after prolonged sleep restriction and subsequent recovery sleep in healthy young men

2018

Purpose Sleep restriction is increasingly common and associated with the development of health problems. We investigated how the neuroendocrine stress systems respond to prolonged sleep restriction and subsequent recovery sleep in healthy young men. Methods After two baseline (BL) nights of 8 h time in bed (TIB), TIB was restricted to 4 h per night for five nights (sleep restriction, SR, n = 15), followed by three recovery nights (REC) of 8 h TIB, representing a busy workweek and a recovery weekend. The control group (n = 8) had 8 h TIB throughout the experiment. A variety of autonomic cardiovascular parameters, together with salivary neuropeptide Y (NPY) and cortisol levels, were assessed.…

The prediction of three driving quality states of simulated driving by psychophysiological variables with sleep-deprived subjects

2005

Intensivsykepleierens vurdering og tilrettelegging av søvn : en kvalitativ studie om intensivsykepleierens erfaring med vurdering og tilrettelegging …

2016

Masteroppgave i spesialsykepleie – Universitetet i Agder 2016 Background: Previous studies have showed that lack of sleep makes ICU patients stressed. In addition, other studies have showed that the ICU nurses’ subjective assessment of ICU patients’ sleep have low correspondence with objective data, like polysomnography. This shows the need for further studies related to the assessment and facilitation of sleep that the ICU nurses are doing. Aim: The aim of this study is to investigate the ICU nurse’s experience of assessment and facilitation of the ICU patient’s sleep, and how sleep can affect the course of the disease. Method: The study has a qualitative approach and in-depth interviews w…

Data mining framework for random access failure detection in LTE networks

2014

Sleeping cell problem is a particular type of cell degradation. There are various software and hardware reasons that might cause such kind of cell outage. In this study a cell becomes sleeping because of Random Access Channel (RACH) failure. This kind of network problem can appear due to misconfiguration, excessive load or software/firmware problem at the Base Station (BS). In practice such failure might cause network performance degradation, which is hardly traceable by an operator. In this paper we present a data mining based framework for the detection of problematic cells. In its core is the analysis of event sequences reported by a User Equipment (UE) to a serving BS. The choice of N i…

“Terve uni on kasvatuksella hankittavissa”. Nukkumisen ohjeistaminen 1800-1900-luvun vaihteen suomalaisissa terveysohjeissa

2017

Artikkelissa tarkastellaan sitä, miten nukkumista ohjeistettiin 1800-luvun lopun ja 1900-luvun alkukymmenten suomalaisessa terveysvalistuksessa ja mitä hyvän unen avulla tavoiteltiin. Artikkelissa kysytään myös, ketkä nukkumisohjeita laativat, kenelle ne oli suunnattu ja millaisesta ajattelutavasta ne kumpusivat. Unihygienia eli nukkumiseen ja liittyvät ohjeistukset olivat osa kansainvälistä hygienialiikettä, joka oli vahvimmillaan juuri 1800-luvun loppupuolella. Ne liittyvät myös suomalaiseen sivistyneistön kasvatusprojektiin, jonka tavoitteena oli vahva, terve ja siveellinen kansa. Artikkelin tutkimuslähteinä ovat terveysoppaat, terveydenhoitoalan lehdet ja nukkumiseen liittyvät ohjeistuk…

Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk

2022

This study aimed to examine 1) adherence to 24-hour movement guidelines over a 2-year follow-up in children aged 6-8 years and 2) association of this adherence with cardiometabolic risk factors. Physical activity and sleep were assessed by a monitor combining heart rate and accelerometry measurements. Screen time was reported by the parents. Body fat percentage, waist circumference, blood glucose, serum insulin, plasma lipids and blood pressure were assessed, and a cardiometabolic risk score was calculated using z-scores. Children were classified as meeting the guidelines if they had on average ≥60min/day of moderate-to-vigorous physical activity during the valid days; ≤120min/day of screen…

Advances in ventilatory treatment for OSAS

2021

Continuous positive airway pressure (CPAP) is the most widely used treatment for obstructive sleep apnea (OSA), and was established four decades ago. An alternative option is to use bilevel ventilation, in order to improve compliance to treatment especially in patients who need a high therapeutic pressure to prevent nocturnal respiratory events. Automatic CPAP or bilevel ventilation are also established among OSA therapeutic choices, and are generally indicated in cases of highly variable therapeutic pressure. The major advances in the field regard OSAS in the context of uncomplicated obesity hypoventilation syndrome (OHS), in which either CPAP or bilevel ventilation yield comparable result…

Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action

2015

Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoates were screened against rhodesain and human cathepsins B and L, and were found to be potent and selective inhibitors of rhodesain. Among them (S,E)-ethyl 5-((S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanamido)-7-methyl-4-oxooct-2-enoate (6) was the most potent, with an IC50 value of 16.4 nm and kinact/Ki=1.6×106 m−1 s−1 against rhodesain. These dipeptidyl enoates display a reversible mode of inhibition at very low concentrations and an irreversible mode at higher concentrations. Inhibition…