Search results for "LENI"
showing 10 items of 756 documents
Selenium bio-enrichment of Mediterranean fruit juices through lactic acid fermentation.
2021
Abstract This work was carried out to elaborate selenium (Se) bio-enriched fermented Mediterranean fruit juices. To this purpose, pomegranate and table red grape juices were added with sodium selenite (Na2SeO3) and fermented by Levilactobacillus brevis CRL 2051 and Fructobacillus tropaeoli CRL 2034 individually or combined. To better evaluate the effect of selenite addition and starter strain inoculums on the total bacterial community of the fruit juices, fermentation trials were performed with raw and pasteurized fruit juices. No statistical significant differences were observed for total mesophilic microorganisms (TMM) and rod-shaped lactic acid bacteria (LAB) levels among raw and pasteur…
Il paesaggio agrario nella Sicilia ellenistico-romana: Alesa e il suo territorio
2008
La ricostruzione del sistema del popolamento rurale e dei modi di sfruttamento delle risorse, all’interno di un comprensorio geograficamente e storicamente determinato, costituisce l’oggetto della ricerca storico-topografica condotta sul territorio di Alesa. L’area di studio è centrata intorno alla città di Alesa, che ne rappresenta il fulcro, storico e geografico insieme, con l’obiettivo di tracciare il rapporto tra centro urbano e territorio circostante, fonte primaria dei mezzi di sussistenza. L’orizzonte cronologico è però più ampio, spaziando da età preistorica al tardo-antico, con la consapevolezza che alcune forme dell’insediamento, insieme ad aspetti riguardanti sia la disponibilità…
The Effect of tRNA
2021
Transfer RNA[Ser]Sec carries multiple post-transcriptional modifications. The A37G mutation in tRNA[Ser]Sec abrogates isopentenylation of base 37 and has a profound effect on selenoprotein expression in mice. Patients with a homozygous pathogenic p.R323Q variant in tRNA-isopentenyl-transferase (TRIT1) show a severe neurological disorder, and hence we wondered whether selenoprotein expression was impaired. Patient fibroblasts with the homozygous p.R323Q variant did not show a general decrease in selenoprotein expression. However, recombinant human TRIT1R323Q had significantly diminished activities towards several tRNA substrates in vitro. We thus engineered mice conditionally deficient in Tr…
Synthesis of polymer materials for use as cell culture substrates
2007
International audience; Up to today, several techniques have been used to maintain cells in culture for studying many aspects of cell biology and physiology. More often, cell culture is dependent on proper anchorage of cells to the growth surface. Thus, poly-L-lysine, fibronectin or laminin are the most commonly used substrates. In this study, electrosynthesized biocompatible polymer films are proposed as an alternative to these standard substrates. The electrosynthesized polymers tested were polyethylenimine, polypropylenimme and polypyrrole. Then, the adhesion, proliferation and morphology of rat neuronal cell lines were investigated on these polymer substrates in an attempt to develop ne…
Over 30% of Patients with Splenic Marginal Zone Lymphoma Express Distinctive Antigen Receptors Utilizing a Single Immunoglogulin Variable Gene: Impli…
2010
Abstract Abstract 634 We systematically explored the immunoglobulin (IG) gene repertoire in 337 cases with splenic marginal-zone lymphoma (SMZL), by far the largest series yet. To resolve classification uncertainties, we included in the analysis only cases with a diagnosis of SMZL based on spleen histopathological findings or cases fulfilling the 2008 SBLG criteria (Matutes et al. Leukemia 2008). We here report that the IG heavy variable (IGHV) gene repertoire in SMZL is remarkably biased, with only three genes accounting for 45.8% of cases (IGHV1-2, 24.9%; IGHV4-34, 12.8%; IGHV3-23: 8.1%, respectively), significantly extending previous similar observations. Particularly for the IGHV1-2 gen…
Distinctive Patterns of Intraclonal Diversification In IGHV1-2*04 Immunoglobulin Receptors of Patients with Splenic Marginal Zone Lymphoma: A of Ongo…
2011
Abstract Abstract 2638 We recently demonstrated that over 30% of cases with splenic marginal-zone lymphoma (SMZL) express distinctive immunoglobulin (IG) receptors that utilize a single polymorphic variant of the IGHV1-2 gene (IGHV1-2*04) and also exhibit restricted antigen-binding site motifs and precise targeting of somatic hypermutation (SHM). On these grounds, we proposed the existence of molecular subtypes of SMZL defined by immunogenetic analysis of the IG receptors with implications for selection by specific (super) antigenic element(s) in the development of at least a major subset of SMZL. In order to gain insight as to whether antigen involvement is relevant only prior to the malig…
The End of Magdalenian in Andalusia: Cueva de Nerja (Spain)
2012
The Solutrean-Magdalenian Transition: a view from the west
2012
Indication for social interaction during the Central European Late Upper Palaeolithic: Evidence from the Magdalenian site of Oelknitz, Structure 1 (T…
2012
Abstract The current paper reports on the faunal assemblage from Structure 1 at the German Magdalenian site of Oelknitz. The composition of the fauna is characterised by a dominance of horse. The horses were exploited for meat and marrow. A strict spatial separation of carcass parts is obvious, also observed at other Magdalenian sites, where the evidence was interpreted in terms of social interaction and food sharing. This is discussed against the contextual background of the site of Oelknitz. It is suggested that the way in which Magdalenians interacted socially is independent of site function.
Metal concentrations and detoxification mechanisms in Solea solea and Solea senegalensis from NW Mediterranean fishing grounds
2013
10 pages, 5 figures, 4 tables