Search results for "LET"
showing 10 items of 23489 documents
THE COMBINED USE OF PRP AND ER,CR: YSGG LASER IN THE TREATMENT OF OSTEONECROSIS OF THE JAWS
2014
In human osteosarcoma 3AB-OS cancer stem cells let-7d seems to have the dual function of oncogene/tumor-suppressor miRNA
2015
Introduction: Osteosarcoma (OS), an aggressive tumor a!ecting adolescents, shows therapy resistance and recurrence which can depend on cancer stem cells (CSCs), the source for tissue renewal and hold malignant potential; thus, OS treatment requires their eradication. Here, using 3AB-OS CSCs previously obtained from the OS-MG63 cells, we focused on the role of let-7d in managing stemness properties of 3AB-OS CSCs. Methods: 3AB-OS CSCs were stably transfected with pCDomH-plasmid, containing mir-let7-d, or empty vector as a control. Cell proliferation and viability were evaluated by EdU and Trypan blue assays, respectively. Sarcosphere and colony assays and wound healing and transwell invasion…
La funzione Morgante. Persistenze e variazioni nel genere comico in ottave tra Cinque e Settecento
2012
Novel inflammatory biomarkers may reflect subclinical inflammation in young healthy adults with obesity
2019
Wstęp: Otyłości często towarzyszy subkliniczny stan zapalny. W ostatnich latach zidentyfikowano kilka nowych markerów stanu zapalnego, których podstawą są wartości poszczególnych elementów morfotycznych krwi — stosunek liczby neutrofilów do limfocytów (NLR), pochodna stosunku liczby neutrofilów do limfocytów (dNLR), stosunek liczby płytek krwi do limfocytów (PLR), stosunek liczby limfocytów do monocytów (LMR), oraz stosunek liczby monocytów do stężenia cholesterolu frakcji HDL (MHR). Potwierdzono, że czynniki te są istotnie skorelowane z uznanymi wskaźnikami stanu zapalnego, takimi jak stężenie białka C-reaktywnego (CRP) i niosą ze sobą wartość prognostyczną w zakresie chorobowości i śmiert…
Oxidation of aromatic alcohols in irradiated aqueous suspensions of commercial and home-prepared rutile TiO(2): a selectivity study.
2008
WOS: 000256241700021
Oxidative stress, oxidative stress-based diseases and Mediterranean diet. Raman spectroscopy monitoring of skin carotenoids in healthy individuals an…
Abstract Evaluating the level of body antioxidants may reveal a more or less severe oxidative stress condition in either healthy people or subjects with pathologies, and can be suggestive for suitable dietary interventions to possibly affect it. In this work taking advantage from the Raman spectroscopic technology to measure the level of skin carotenoids in a simple and non-invasive manner, healthy people (age 15 to 70, n=155) and women who had surgery for breast cancer (BC) (age 38 to 76, n=71) have been screened to assess to what extent an increased intake of fruit and vegetables (healthy people and patients), associated with diets based on a classical Mediterranean style and that did not…
Ozone depletion in tropospheric volcanic plumes
2010
We measured ozone (O3) concentrations in the atmospheric plumes of the volcanoes St. Augustine (1976), Mt. Etna (2004, 2009) and Eyjafjallajökull (2010) and found O3 to be strongly depleted compared to the background at each volcano. At Mt. Etna O3 was depleted within tens of seconds from the crater, the age of the St. Augustine plumes was on the order of hours, whereas the O3 destruction in the plume of Eyjafjallajökull was maintained in 1–9 day old plumes. The most likely cause for this O3 destruction are catalytic bromine reactions as suggested by a model that manages to reproduce the very early destruction of O3 but also shows that O3 destruction is ongoing for several days. Given the o…
Natural Halogen Emissions to the Atmosphere: Sources, Flux, and Environmental Impact
2022
Understanding the atmospheric geochemical cycle of both natural and anthropogenic halogens is important because of the detrimental effect halogens have on the environment, notably on tropospheric and stratospheric ozone. Oceans are the primary natural source for atmospheric Cl, F, Br, and I, but anthropogenic emissions are still important, especially for Cl. While emissions of human-made halocarbons (e.g., chlorofluorocarbons or CFCs) are expected to continue to decrease allowing progressive stratospheric ozone recovery, volcanic activity (e.g., clusters of mid-scale explosive eruptions or large-scale explosive eruptions) might disturb this recovery over the next decades. This review provid…
Variational versus pseudomonotone operator approach in parameter-dependent nonlinear elliptic problems
2013
We study the existence of nontrivial solutions of parameter-dependent quasilinear elliptic Dirichlet problems of the form $-\Delta u = \lambda f(u)$ in $\Omega$, $u = 0$ on $\partial\Omega$, in a bounded domain $\Omega$ with sufficiently smooth boundary, where $\lambda$ is a real parameter and $\Delta_p$ denotes the p-Laplacian. Recently the authors obtained multiplicity results by employing an abstract localization principle of critical points of functional of the form $\Phi-\lambda\Psi$ on open subleveis of $\Phi$, i.e., of sets of the form $\Phi^{-1}(-\infty,r)$, combined with differential inequality techniques and topological arguments. Unlike in those recent papers by the authors, the …
Gradient nonlinear elliptic systems driven by a (p,q)-laplacian operator
2017
In this paper, using variational methods and critical point theorems, we prove the existence of multiple weak solutions for a gradient nonlinear Dirichlet elliptic system driven by a (p, q)-Laplacian operator.