Search results for "LF"

La Reggia di Venaria Reale in Italy and Palacio Real de Aranjuez in Spain: history, restoration and significance, comparative study between Two Royal…

2017

La investigación relaciona dos sitios reales, La Reggia di Venaria Reale en Italia y el Palacio Real de Aranjuez en España, confrontando su desarrollo histórico y arquitectónico, las obras de restauración llevadas a cabo, los criterios para su inclusión en la Lista de Patrimonio Mundial y su uso hoy en día como museos. El estudio comparativo muestra cómo ambos palacios se usaban inicialmente como residencias de caza en lugares con abundancia de agua y pesca. Además, los dos están ubicados cerca de las capitales políticas de su tiempo; esto es, Turín y Madrid. El hecho que el mismo arquitecto – Filippo Juvarra estuviera presente en ambas residencias reales contribuye a las similitudes, y en …

Revidering, planering och olika pausmönster vid nominalfraser under skrivprocessen

1997

Filmas "Paradīze 89" naratīva analīze un filmas vēstījums auditorijā

2018

Bakalaura darba ‘’Filmas ‘’Paradīze 89’’ naratīva analīze un filmas vēstījums auditorijā’’ galvenais mērķis ir noskaidrot un izanalizēt spēlfilmas ‘’Paradīze 89’’ pamatideju, filmas vēstījumu un struktūru. Pētījuma gaitā tiek apskatīts naratīvs un analizēta filmas struktūra pēc A.Ž. Greimsa aktantu naratīva shēmas. Kā arī veidotas, realizētas un analizētas intervijas ar filmas režisori Madaru Dišleri un pieciem dažāda vecuma pārstāvjiem pēc filmas noskatīšanās. Pētījuma veikšanā tika izmantota naratīva analīze, kvalitatīvā kontentanalīze un daļēji strukturētās intervijas. Darba uzdevumi ir noskaidrot filmas vēstījumu pēc režisores perspektīvas un kā šo vēstījumu uztver auditorija dažādās ve…

Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

2003

Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…

Inhibition of Protein Isoprenylation Impairs Rho-Regulated Early Cellular Response to Genotoxic Stress

2000

Activation of c-Jun N-terminal kinases (JNKs) and nuclear factor-kappaB (NF-kappaB) are early cellular responses to genotoxic stress involved in the regulation of gene expression. Pretreatment of cells with the hydroxymethyl glutaryl-CoA reductase inhibitor lovastatin blocked stimulation of JNK1 activity by UV irradiation and by treatment with the alkylating compound methyl methanesulfonate but did not affect activation of extracellular signal-regulated kinase 2 by UV light. Lovastatin also attenuated UV-induced degradation of the NF-kappaB inhibitor IkappaBalpha. The effects of lovastatin on UV-triggered stimulation of JNK1 as well as on IkappaBalpha degradation were reverted by cotreatmen…

Inhibition of Rho modulates cytokine-induced prostaglandin E2 formation in renal mesangial cells.

2003

Stimulation of rat mesangial cells for 24 h with interleukin-1β(IL-1β) plus forskolin (Fk) leads to a marked increase in prostaglandin E 2 (PGE 2 ) synthesis. This effect is further enhanced by the small G-protein Rho inhibitor toxin A. A similar increase in PGE 2 formation is obtained with Y27632, a Rho-dependent kinase inhibitor, and with lovastatin, a hydroxymethylglutaryl-coenzyme A inhibitor which depletes cells from geranylgeranyl moieties and thus blocks Rho activation. In parallel to the increased PGE 2 synthesis, a potentiation of IL-1β-induced secretory group IIA phospholipases A 2 (sPLA 2 -IIA) protein expression also occurs by Rho inhibition. However, only toxin A triggers an in…

Cypriana Norwida słowo i druk

2009

Sinergismo d'azione tra protocollo riabilitativo ed anti-TNFalfa versus terapia biologica

2012

La spondilite anchilosante è una malattia infiammatoria cronica ad eziologia sconosciuta che colpisce prevalentemente lo scheletro assile ma che può coinvolgere anche le entesi periferiche. Presso l'ambulatorio dell'U.O.C. di Riabilitazione dell'A.U.O.P. "Paolo Giaccone" di Palermo, in diciotto mesi (Aprile 2011-Maggio 2012) sono stati arruolati 24 soggetti (6 donne- 18 uomini). affetti da Spondilite Anchilosante HLA B27 diagnosticata secondo i criteri europei. Il presente studio ha mostrato efficacia nel trattamento di pazienti con SA mediante un progetto-programma riabilitativo mirato e specifico per distretto articolare. Svolgere con regolarità e costanza l'esercizio terapeutico in assoc…

Effetto combinato di cadmio e sulfonammidici sullo sviluppo degli embrioni di riccio di mare: un'indagine molecolare

2013

Défis à relever pour la politique budgétaire en Amérique latine en matière de stabilisation et de redistribution

2016

Cet article se propose d'étudier les réponses offertes par la politique fiscale en Amérique latine dans la situation actuelle " d'atterrissage en douceur ". En fait, il apparaît que la région est exposée à un risque de choc externe de pays développés et la Chine à un risque politique. Dans ces conditions, la politique fiscale a un rôle important à jouer pour gérer ces risques en se centrant sur ses fonctions de stabilisation et de distribution. En outre, nous proposons un système de plusieurs mesures pour chaque fonction. Enfin, nous démontrons que les pays latino-américains ne souffrent pas de contrainte du financement pour appliquer nos recommandations.