Search results for "LF"
showing 10 items of 12543 documents
Not just daycare: nordic mothers in research, development and innovation navigating work and childcare
2022
Nordic welfare policies mitigate work–childcare reconciliation; however, they are not enough for mothers working in intensive work cultures. In addition, there are differences among the three Nordic states in both work–family policies and cultural norms as to how they should be used. In this article, we study the resources mothers who work in research, development and innovation (R&D&I) in Finland, Norway and Sweden rely on in their work–childcare reconciliation. Thematic analysis of interviews with 74 professionals resulted in identifying four main resources: father involvement, parental leave system and daycare, flexible working, and grandparent help and networks. Our analysis brings to v…
The Use of Multimodal Resources by Technical Managers and Their Peers in Meetings Using English as the Business Lingua Franca
2020
Background: Engineers increasingly work and advance their careers in international business settings. As technical managers, they need management and technical skills when working with different stakeholders with whom they may not share a common first language. Studies have revealed that informal oral communication skills are of prime importance for global engineers who face challenges in building shared meaning and formulating clear messages in meetings with non-native speakers of English. This article proposes that studying the use of multimodal resources (spoken language, gaze, gestures, and objects) in meetings can unpack how work tasks are accomplished in business through different com…
Transferencia génica hepática hidrodinámica en modelos de cerdo in vivo y segmento humano ex vivo
2015
Introducción: La terapia génica es una estrategia terapéutica que pretende utilizar ácidos nucleicos como medicamentos para el tratamiento temporal o permanente de patologías hereditarias o adquiridas. En base al vehículo utilizado para entregar el gen, podemos clasificar la terapia génica en dos grupos: la terapia génica viral (vectores virales) y la terapia génica no viral (vectores no virales o ADN desnudo). La terapia no viral resulta menos eficiente pero más segura. La hidrofección (transferencia génica hidrodinámica) ha mostrado un gran potencial, con resultados terapéuticos en ratón. Sin embargo, cuando la hidrofección se ha trasladado a animales de mayor tamaño, el procedimiento ha …
Edición génica del gen SERPINA1 mediante el uso de CRISPR/Cas9 en células sanguíneas de pacientes con déficit de alfa-1 antitripsina
2022
Introducción. El déficit de alfa-1 antitripsina (DAAT) es una enfermedad rara caracterizada por niveles bajos en sangre de una proteína denominada alfa-1 antitripsina (AAT), principal enzima antiproteasa del suero. El DAAT está provocado por mutaciones en el gen SERPINA1, que codifica para la AAT. Las dos mutaciones más frecuentes se denominan Pi*Z y Pi*S, provocando la primera una sintomatología más grave. A la variante normal se le denomina Pi*M. CRISPR/Cas9 es una herramienta de edición génica adaptada del sistema de inmunidad adquirida presente en bacterias y arqueas que consiste en una endonucleasa, Cas9, guiada por una molécula de RNA simple (sgRNA), complementaria al gen diana. Objet…
Measuring Health Promotion in Sports Club Settings: A Modified Delphi Study
2019
Settings-based approaches have become an increasing health promotion focus since the World Health Organization’s 1986 Ottawa Charter. While schools, cities, and prisons have implemented this approach, its development within sports environments is recent. Sports are a popular leisure-time activity, requiring validated tools to measure health promotion activity. This study’s aim was to develop a measurement tool based on international consensus that measures perceptions of health promotion within sports clubs. It is grounded in the settings-based approach and builds on theory from previous works expanding their context and knowledge. An online, three-round international Delphi study was cond…
Habitus and care : investigating welfare service workers' agency
2014
Diritto del lavoro e Terzo settore. Occupazione e welfare partenariale dopo il d.lgs. n. 117/2017
2020
La riforma del Terzo settore –di cui il d.lgs. 3 luglio 2017, n. 117 costituisce il baricentro – ha segnato un netto punto di discontinuità rispetto alla tradizionale considerazione delle iniziative solidaristiche della società civile come fenomeno residuale rispetto all’intervento dello Stato e del mercato. La codificazione di un nuovo diritto degli Enti del Terzo settore, finalmente dotato di linee di disciplina autonome e uniformi, ha infatti fornito una precisa identità giuridica ad una realtàche per molti anni ha disposto di una matrice definitoria soltanto sul piano socio-culturale. Lo studio esamina le innovazioni legislative nella prospettiva lavoristica, con l’obiettivo di verifica…
CCDC 1958345: Experimental Crystal Structure Determination
2020
Related Article: Raphael C. A. Vaz, Isabela O. Esteves, Willian X. C. Oliveira, João Honorato, Felipe T. Martins, Lippy F. Marques, Guilherme L. dos Santos, Ricardo O. Freire, Larissa T. Jesus, Emerson F. Pedroso, Wallace C. Nunes, Miguel Julve, Cynthia L. M. Pereira|2020|Dalton Trans.|49|16106|doi:10.1039/D0DT02497J
CCDC 1538407: Experimental Crystal Structure Determination
2018
Related Article: Ioannis Mylonas-Margaritis, Julia Mayans, Panagiota S. Perlepe, Catherine P. Raptopoulou, Vassilis Psycharis, Konstantina I. Alexopoulou, Albert Escuer, Spyros P. Perlepes|2017|Curr.Inorg.Chem.|7|48|doi:10.2174/1877944107666170705105817
CCDC 1873815: Experimental Crystal Structure Determination
2019
Related Article: Kristina S. Kisel, Alexei S. Melnikov, Elena V. Grachova, Antti J. Karttunen, Antonio Doménech-Carbó, Kirill Yu. Monakhov, Valentin G. Semenov, Sergey P. Tunik, Igor O. Koshevoy|2019|Inorg.Chem.|58|1988|doi:10.1021/acs.inorgchem.8b02974