Search results for "LMA"

Contrasting temperature responses in seasonal timing of cercariae shedding by Rhipidocotyle trematodes

2022

AbstractGlobal warming is likely to lengthen the seasonal duration of larval release by parasites. We exposed freshwater mussel hosts, Anodonta anatina, from 2 high-latitude populations to high, intermediate and low temperatures throughout the annual cercarial shedding period of the sympatric trematodes Rhipidocotyle fennica and R. campanula, sharing the same transmission pathway. At the individual host level, under warmer conditions, the timing of the cercarial release in both parasite species shifted towards seasonally earlier period while its duration did not change. At the host population level, evidence for the lengthening of larvae shedding period with warming was found for R. fennica…

Sintētiska pieeja enantiotīro ciklisko sulfinamīdu sintēzei

2021

Sintētiska pieeja enantiotīro ciklisko sulfinamīdu iegūšanai. Jeršovs G. Zinātniskie vadītāji: Dr. chem. Sūna E., Mg.chem. Kazak M. Maģistra darbs, 92 lappuses, 40 attēli, 4 tabulas, 71 literatūras avots. Latviešu valodā. Maģistra darba ietvaros ir izstrādātas jaunas sintētiskās metodes SN2 un SN2’ tipa iekšmolekulārai sulfinamīdu S-alkilēšanai. Ir izveidots substrātu klāsts SN2’ tipa S-ciklizācijai un piedāvāts tās augstas diastereoselektevitātes skaidrojums. Literatūras apskatā apkopota informācija par sulfinamīdu iekšmolekulārām ciklizācijām un enantiotīro S (VI) atvasinājumu sintēzi no sulfinamīdiem.

Päähiirtä käyttävän CP-nuoren tietokoneavusteinen musiikinohjausprosessi

2008

Exponential instability in the fractional Calder\'on problem

2017

In this note we prove the exponential instability of the fractional Calder\'on problem and thus prove the optimality of the logarithmic stability estimate from \cite{RS17}. In order to infer this result, we follow the strategy introduced by Mandache in \cite{M01} for the standard Calder\'on problem. Here we exploit a close relation between the fractional Calder\'on problem and the classical Poisson operator. Moreover, using the construction of a suitable orthonormal basis, we also prove (almost) optimality of the Runge approximation result for the fractional Laplacian, which was derived in \cite{RS17}. Finally, in one dimension, we show a close relation between the fractional Calder\'on pro…

Cancer Prevention with Resistant Starch in Lynch Syndrome Patients in the CAPP2-Randomized Placebo Controlled Trial : Planned 10-Year Follow-up

2022

Abstract The CAPP2 trial investigated the long-term effects of aspirin and resistant starch on cancer incidence in patients with Lynch syndrome (LS). Participants with LS were randomized double-blind to 30 g resistant starch (RS) daily or placebo for up to 4 years. We present long-term cancer outcomes based on the planned 10-year follow-up from recruitment, supplemented by National Cancer Registry data to 20 years in England, Wales, and Finland. Overall, 463 participants received RS and 455 participants received placebo. After up to 20 years follow-up, there was no difference in colorectal cancer incidence (n = 52 diagnosed with colorectal cancer among those randomized to RS against n = 53…

Exercise intervention protocol in children and young adults with cerebral palsy : the effects of strength, flexibility and gait training on physical …

2021

Abstract Background Individuals with cerebral palsy (CP) have problems in everyday tasks such as walking and climbing stairs due to a combination of neuromuscular impairments such as spasticity, muscle weakness, reduced joint flexibility and poor coordination. Development of evidence-based interventions are in pivotal role in the development of better targeted rehabilitation of CP, and thus in maintaining their motor function and wellbeing. Our aim is to investigate the efficacy of an individually tailored, multifaceted exercise intervention (EXECP) in children and young adults with CP. EXECP is composed of strength, flexibility and gait training. Furthermore, this study aims to verify the …

Looking for Feminist Pragmatist Roots of Degrowth Ideas: Jane Addams, Charlotte Perkins Gilman, Caroline Bartlett Crane

2022

The aim of the paper is a search of feminist pragmatist roots of degrowth ideas. The starting point is the question of whether in views of the members of the Progressive Movement the idea of progress has always implied the economic (and industrial) growth. Searching for counter-examples leads me to ideas of ecofeminism and feminist critics of capitalism in the previous turn of the centuries. The ideas of ecofeminism were developed by women associated with the Department of Sociology at the University of Chicago and the social settlement Hull House. They observed a link between the exploitation of subordinate members of a society and the degradation of nature in Western cultural values. The …

Characterization of fusion from without induced by herpes simplex virus

1991

The process of fusion from without (FFWO) induced by herpes simplex virus (HSV) was analyzed by using various inhibitors and compared to fusion from within (FFWI). The fate of certain elements of the cytoskeleton after FFWO was also investigated. Our experiments demonstrate FFWO as a very suitable system for study of early virus-cell interactions. Zn++ ions proved inhibitory for penetration whilst pretreatment of cells with Ca++ ions before infection enhanced FFWO activity. Dissociation of penetration from the fusion process itself was possible by use of Zn++ ions, low pH-treatment and antiserum on the one hand and N-ethylmaleimide and cytochalasin D on the other. Penetration itself needs o…

Le piazze quadrate ad angoli chiusi nelle città siciliane di fondazione. Alcuni casi di studio

2013

La piazza delle città fondate in Sicilia tra Cinquecento e Settecento dalla classe baronale accoglie solitamente la sede del potere politico e religioso, palesata nel palazzo del fondatore e nella chiesa Madre, e con la sua posizione orienta la trama viaria, che è di regola a maglia ortogonale. Un caso particolare, non molto diffuso in Sicilia, è rappresentato dalla piazza ad angoli chiusi, attraversata nella mezzeria dei lati da una croce di strade, i cui esempi più noti possono individuarsi nelle piazze di Cattolica Eraclea (1610) e Palma di Montechiaro (1637), che nel testo vengono analizzate.

Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca2+-stimulated exocytosis of …

1996

Ca2+ stimulates exocytosis in permeabilized insulin-secreting cells. To investigate the putative cytosolic components involved in the Ca2+ response, HIT-T15 cells (a pancreatic B-cell line) were permeabilized with streptolysin-O, a procedure that allows rapid exchange of soluble components including macromolecules. We found that in this cell preparation the secretory response to Ca2+ but not to guanosine 5'-[gamma-thio]triphosphate was lost as a function of time and could be restored by rat brain cytosol in a concentration-dependent manner. Reconstitutive activity of rat brain cytosol was found in a high-molecular-mass heat-labile partially N-ethylmaleimide(NEM)-sensitive fraction. The NEM-…