Search results for "LMI"
showing 10 items of 1764 documents
Lean-ohjelmistokehityksen käyttöönoton jälkeisiä ohjelmistokehitysnopeutta rajoittavia tekijöitä
2011
Tutkielmassa tarkastellaan, mitä Lean ja Lean-ohjelmistokehitys ovat, mitä Lean-ohjelmistokehitys tarkoittaa tapausyrityksessä, eli Sysdrone Oy:ssä, sekä mitkä ovat tapausyrityksen merkittävimmät ohjelmistokehitysnopeutta rajoittavat tekijät puoli vuotta Lean-ohjelmistokehityksen käyttöönoton jälkeen. Tutkimus toteutettiin tapaustutkimuksena, jossa tutkimusaineistoa kerättiin puolen vuoden aikajaksolta. Johtopäätöksinä merkittävimmiksi rajoittaviksi tekijöiksi tunnistettiin tuotoslista, uudet teknologiat, projektien riittämätön läpinäkyvyys, tiettyjen hen-kilöiden ylikuormitus, puutteet prosessien noudattamisessa, dokumentointi sekä asiakaskommunikaatio.
(Table 1) Geochemistry of ODP Site 160-963 sediments
2010
The Mediterranean Sea acts as a miniature ocean with the development of its own conveyor belt. It constitutes an ideal location to study and forecast how the marine environment responds to rapid climatic change. Here we present a palaeoenvironmental study carried out on the sediments of ODP Site 963, recovered in the Sicily Channel, the sill which divides the western from the eastern Mediterranean basin. We focused on the transition between the penultimate glacial (MIS 6) and the last interglacial (MIS 5), between approximately 130 and 115 kyr BP. A novel approach is proposed, taking into account centennial-scale geochemical data on major elements, selected trace elements, and yttrium and R…
A bug's life: Delving into the challenges of helminth microbiome studies.
2020
The body of vertebrates is inhabited by trillions of microorganisms, i.e. viruses, archaea, bacteria and unicellular eukaryotes, together referred to as the ‘microbiota’. Similarly, vertebrates also host a plethora of parasitic worms (the ‘macrobiota’), some of which share their environment with the microbiota inhabiting the gastrointestinal tract [1]. Complex interactions between the helminths and the gut microbiota have been associated with establishment of parasite infection, disease manifestations, and host immune-modulation [2, 3]. Remarkably, not only enteric helminths alter the 26 gut microbiome composition [4], but also the infection with blood flukes of the genus Schistosoma has be…
Yhteistyön mahdollisuudet – lukiokoulutukseen valmistava koulutus kielellistyvässä maailmassa
2018
Tassa tutkimuksessa selvitetaan sita, millaisia kasityksia rehtoreilla, opettajilla ja opiskelijoilla on vuorovaikutuksen mahdollistavasta toiminnasta eli yhteistyosta Lukiokoulutukseen valmistavan koulutuksen (LUVA) ja muun lukiotoiminnan valilla. Edellisen lisaksi tarkastellaan sita, ilmeneeko LUVA-koulutuksessa aineiston perusteella kielenoppimista tukevaa eri kielten limittaista kayttoa (engl. translanguaging ). Tutkimuksen teoreettinen tausta pohjautuu kielenoppimisen kayttopohjaiseen ajatteluun eli siihen, etta oppimisessa tarkeimpana nahdaan kielenkaytto ja vuorovaikutus. Taman artikkelin keskeinen teoreettinen kasite on translanguaging , joka nahdaan vastakohtana yksikielisyyden …
Percepción visual y traducción audiovisual: la mirada dirigida
2012
En este trabajo, partimos de la premisa de que las destrezas perceptuales innatas necesarias para entender una obra audiovisual son idénticas a las de la percepción visual natural (Grodal 1999: 76). La percepción es una forma inconsciente y natural de interpretar nuestro entorno gracias a la experiencia previa y al aprendizaje. Sostenemos, en contra de la creencia profundamente arraigada en Occidente de que la imagen es universal y verdadera, que la percepción visual es un proceso cognitivo determinado por la experiencia previa, el ambiente, el contexto, los valores culturales y la motivación. En este trabajo vamos a estudiar la aplicación de las investigaciones cognitivas sobre percepción …
Casting the light on cinema – how luminance and contrast patterns create meaning
2012
The question of meaning creation has always been at the core of cross-disciplinary scholarly research. Considered from the cinematographic perspective, it inevitably evokes correlations with plot and dialogue. However, the conveyance of significance in films does not rely solely on the verbal channel, but also manifests itself in the visual layer, ranging from facial expressions, setting and locations, to directorial editing choices. Elevating the role of the how of film making, this article focuses on the influence of light and contrast patterns on the reading of cinema. In order to highlight their position in film text vocabulary and recognize their relevance in film translations and adap…
Linnansalmen Haloset : sukutilan omaistajanvaihdokset perheyhteisön taitekohtina
2022
Halosen taiteilijasuvun talonpoikainen suurperhe on tuttu Suomen taidehistoriasta. Sukutila ja talollisen asema eivät kuitenkaan olleet heille itsestään selvä vuosisatainen jatkumo. Myös suurperhe oli enemmän ajoittainen välivaihe tilanomistajuudessa kuin pysyvä sukurakkauden ilmentymä. Tässä artikkelissa tarkastellaan Halosen sukutilan omistajanvaihdoksia perheyhteisön taitekohtina. peerReviewed
Mitochondrial respiration on rumenic and linoleic acids
2001
Rumenic acid ( cis -9, trans -11-C 18:2 ) represents approx. 80% of conjugated linoleic acid (CLA) in dairy products. CLA has been shown to exert beneficial effects on health, but little work has been devoted to the ability to oxidize CLA isomers and the role of these isomers in the modulation of β-oxidation flux. In the present study, respiration on rumenic acid was compared with that on linoleic acid ( cis -9, cis -12-C 18:2 ) with the use of rat liver mitochondria. In state-3, respiration was decreased by half with rumenic acid in comparison with linoleic acid. In the uncoupled state, respiration on CLA remained 30% lower. The lower ability to oxidize CLA was investigated through charact…
Two-step impact of Amphotericin B (AmB) on lipid membranes: ESR experiment and computer simulations.
2013
In this study, the electron spin resonance (ESR) method was used to examine the effect of Amphotericin B (AmB) molecules on the fluidity of model membranes made of dipalmitoylphosphatidylcholine (DPPC). The changes occurring under increased AmB concentrations in the spectroscopic parameters of spin probes placed in liposomes were determined. Three probes were used, penetrating the membrane at different depths which allowed the changes in its fluidity to be found in the transverse section. A computer model of the surface layer of membrane, with AmB admixture, was developed and subjected to computer simulation. The effect of changing concentration of the admixture on the binding energy in the…
INTERACTION OF MACROMOLECULAR PRO-DRUGS WITH LIPID MODEL MEMBRANE - CALORIMETRIC STUDY OF 4-BIPHENYLACETIC ACID LINKED TO ALPHA,BETA-POLY(N-HYDROXYET…
1990
The effect of 4-biphenylacetic acid (BPAA) covalently linked to α,β-poly(N-hydroxyethyl)-dl-aspartamide (PHEA) on the thermotropic properties of dipalmitoylphosphatidylcholine (DPPC) liposomes was investigated by differential scanning calorimetry (DSC). Addition of increasing amounts of PHEA-BPAA adduct to a suspension of phospholipid vesicles modified the thermotropic gel-to-liquid crystalline phase transition by decreasing the enthalpy changes ΔH with concomitant broadening of the peak without variations in the transition temperature (Tm). These effects are interpreted in terms of a deep interaction of BPAA bound to the polymer with the apolar moiety of the lipid bilayer. The amount of dr…