Search results for "LMIs"

Cardiovascular outcomes in patients at high cardiovascular risk with previous myocardial infarction or stroke.

2021

BACKGROUND Guidelines recommend to start blood pressure (BP)-lowering drugs also according to cardiovascular risk including history of cardiovascular events. We hypothesized that in patients with a history of myocardial infarction (MI), stroke, both or none of those, the index events predict the next event and have different SBP risk associations to different cardiovascular outcomes. DESIGN AND MEASUREMENTS In this pooled posthoc, nonprespecified analysis, we assessed outcome data from high-risk patients aged 55 years or older with a history of cardiovascular events or proven cardiovascular disease, randomized to the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint…

Renal outcomes and blood pressure patterns in diabetic and nondiabetic individuals at high cardiovascular risk

2021

Background Diabetes and hypertension are risk factors for renal and cardiovascular outcomes. Data on the association of achieved blood pressure (BP) with renal outcomes in patients with and without diabetes are sparse. We investigated the association of achieved SBP, DBP with renal outcomes and urinary albumin excretion (UAE) in people with vascular disease. Methods In this pooled analysis, we assessed renal outcome data from high-risk patients aged 55 years or older with a history of cardiovascular disease, 70% of whom had hypertension, randomized to The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial and to Telmisartan Randomized Assessment Study in ACE In…

Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials

2017

Summary Background Studies have challenged the appropriateness of accepted blood pressure targets. We hypothesised that different levels of low blood pressure are associated with benefit for some, but harm for other outcomes. Methods In this analysis, we assessed the previously reported outcome data from high-risk patients aged 55 years or older with a history of cardiovascular disease, 70% of whom had hypertension, from the ONTARGET and TRANSCEND trials investigating ramipril, telmisartan, and their combination, with a median follow-up of 56 months. Detailed descriptions of randomisation and intervention have already been reported. We analysed the associations between mean blood pressure a…

Cardiovascular outcomes and achieved blood pressure in patients with and without diabetes at high cardiovascular risk

2019

Abstract Aims Studies have shown a non-linear relationship between systolic blood pressure (SBP) and diastolic blood pressure (DBP) and outcomes, with increased risk observed at both low and high blood pressure (BP) levels. We hypothesized that the BP-risk association is different in individuals with and without diabetes at high cardiovascular risk. Methods and results We identified patients with (N = 11 487) or without diabetes (N = 19 450), from 30 937 patients, from 133 centres in 44 countries with a median follow-up of 56 months in the ONTARGET/TRANSCEND studies. Patients had a prior history of stroke, myocardial infarction (MI), peripheral artery disease, or were high-risk diabetics. P…

Learning via Summarizing Infographics Assignment in Software Engineering Management e-Course?

2020

This Research-to-Practice, Work in Progress Paper focuses on how learners experience creation of infographics as a summarizing assignment in an advanced level e-course on software engineering management (SEM). We have previously investigated how learners perceive infographics as a repeated reflection assignment during a requirements engineering e-course. To complement this research project, we studied how learners experience the use of infographics as a method for summarizing a whole software engineering management course in e-education setting. The SEM course participants (N=36) found that infographics as a summarizing assignment required complex learning that was altogether deemed highly …

Employees’ challenges and needs for reskilling when working with software robots

2022

Software robots are becoming increasingly adopted in different industries. The growing rate of automatization will affect more and more people and will result in changes in businesses of all sizes. Impacts can be observed at both the organizational and individual employee levels. A growing number of studies of software robots’ advantages and disadvantages on an organizational or industry-specific level have been carried out. However, there is limited knowledge about the employees’ perceptions of challenges and new skills needed when working with software robots. This study addresses this gap by using open-ended questionnaire responses from employees who have worked with software robots. Thi…

A root cause analysis method for preventing erratic behavior in software development: PEBA

2019

Measures taken to prevent faults from being introduced or going undetected can secure development of highly reliable software systems. One such measure is analyzing root causes of recurring faults and preventing them from appearing again. Previous methods developed for this purpose have been reactive in nature and relied heavily on fault reporting mechanisms of ogranizations. Additionally, previous efforts lack a defined mechanism for innovating corrective actions. In this study, we strive to complement the existing methods by introducing a proactive and qualitative method that does not rely on fault data. During the course of the research, in addition to an extensive literature search, an …

SDN controllers security issues

2017

Software-Defined Networking (SDN) is essentially varying the way we design and manage networks, which makes a communication network programmable. In SDN, a logically centralized controller has straight control over the packet-handling functions of the network switches, using a standard, open API (Application Programming Interface) such as OpenFlow. OpenFlow is a broadly used protocol for software-defined networks (SDNs) that presents a new model in which the control plane is inattentive from the forwarding plane for the network devices. In SDN approach centralized entities called "controllers" perform like network operating systems run dissimilar applications that accomplish and control the…

Understanding and analyzing SQL/CLI database usage of Java software: empirical study

2005

Pilvitallennuspalvelut : kuluttajasovelluksien näkökulma

2012

Pilvitallennuspalvelut ovat tehneet voimakkaasti tuloaan älypuhelimien yleistyttyä. Mobiililaitteissa on usein rajallinen määrä tallennustilaa ja parhaaksi ratkaisuksi on nähty tietojen tallentaminen pilveen. Tällä kirjallisuuteen perustuvalla tutkielmalla on tarkoitus tuoda esille pilvilaskennan pääpiirteet, sekä tarkastella erilaisten kuluttajille suunnattujen tallennuspalvelusovelluksien ominaisuuksia. Lisäksi otetaan katsaus liiketoiminnassa hyödynnettyihin liiketoimintamalleihin. Keskeisimpinä löydöksinä huomataan, että palveluntarjoajan ekosysteemi tai ekosysteemittömyys vaikuttaa joissakin tapauksissa merkittävästi palvelun ominaisuuksiin ja sen toimintaan eri käyttöjärjestelmissä. E…