Search results for "LOAD"

Vinylcyclopropane [3+2] Cycloaddition with Acetylenic Sulfones Based on Visible Light Photocatalysis

2021

We describe the first intermolecular visible light [3+2] cycloaddition reaction being performed on a meta photocycloadduct employing acetylenic sulfones. The developed methodology exploits the advantages of combining UV and Visible light in a two-step sequence that provides a photogenerated cyclopropane which, through a strain-release process, generates a new cyclopentane ring while increasing significally the molecular complexity. This strategy could be extended to simpler vinylcyclopropanes.

Tension causes structural unfolding of intracellular intermediate filaments

2020

AbstractIntermediate filament (IF) proteins are a class of proteins that constitute different filamentous structures in mammalian cells. As such, IF proteins are part of the load-bearing cytoskeleton and support the nuclear envelope. Molecular dynamics simulations have shown that IF proteins undergo secondary structural changes to compensate mechanical loads, which has been confirmed by experimental in vitro studies on IF hydrogels. However, the structural response of intracellular IF to mechanical load has yet to be elucidated in cellulo. Here, we use in situ nonlinear Raman imaging combined with multivariate data analysis to quantify the intracellular secondary structure of the IF cytoske…

A Dendrimer Chiroptical Switch Based on the Reversible Intramolecular Photoreaction of Anthracene and Benzene Rings

2010

A series of Fréchet-type dendrimers with 9-benzyloxymethylanthracene cores were synthesized and characterized. The chiral source for the dendrimers was an (S)-2-methyl-1-butoxy group in the 3-position of the benzene ring. Irradiation at 366 nm of a dilute benzene solution led to the formation of two diastereomers (1:1) through a quantitative intramolecular [4pi+4pi] cycloaddition between the central anthracene ring and the neighboring benzene ring. The process can be reversed with 254 nm UV light or heat. The benzene rings in the dendrons work as a light-harvesting system. The optical rotation values measured for the reversible process showed fatigue resistance. Thus, a promising new type o…

Measurement uncertainty impact on simplified load flow analysis in MV smart grids

2018

This work is focused on the measurement uncertainty impact on load flow analysis in medium voltage (MV) distribution networks. In more detail, the paper presents the uncertainty evaluation of a simplified load flow algorithm, which is based on the load power measurements at each secondary substation and one voltage measurement at the slack bus (i.e. the voltage at the MV bus bars of the primary substation). To reduce the costs of the monitoring system, the load flow algorithm makes use of LV load power measurements for all the substations except those of MV users, where MV transducers are usually already installed. The uncertainties on the algorithm input quantities (load powers and slack b…

2015

Characterization of host-pathogen interactions is a fundamental approach in microbiological and immunological oriented disciplines. It is commonly accepted that host cells start to change their phenotype after engulfing pathogens. Techniques such as real time PCR or ELISA were used to characterize the genes encoding proteins that are associated either with pathogen elimination or immune escape mechanisms. Most of such studies were performed in vitro using primary host cells or cell lines. Consequently, the data generated with such approaches reflect the global RNA expression or protein amount recovered from all cells in culture. This is justified when all host cells harbor an equal amount o…

Association between internal load responses and recovery ability in U19 professional soccer players: A machine learning approach

2023

Background The objective of soccer training load (TL) is enhancing players’ performance while minimizing the possible negative effects induced by fatigue. In this regard, monitoring workloads and recovery is necessary to avoid overload and injuries. Given the controversial results found in literature, this study aims to better understand the complex relationship between internal training load (IL) by using rating of perceived exertion (RPE), recovery, and availability (i.e., subjective players’ readiness status). Methods In this cross-sectional study, twenty-two-professional soccer players (age: 18.5 ± 0.4 years, height: 177 ± 6 cm, weight: 67 ± 6.7 kg) competing in the U19 Italian Champion…

<title>Structure analysis of the Polish academic information society using MDS method</title>

2006

The article presents the methodology of webometrics research and analysis aiming at determining similar features of objects belonging to the Polish information society, which uses the Internet and its www resources for communication purposes. In particular, the analysis applies to the selected Polish technical universities. The research was carried out in several phases - on different data groups - with regards to the Internet space and time changes. The results have been presented in a form of two and three-dimensional topography maps. For the purposes of this analysis, the computer methods of multidimensional scaling were used. The research will be further continued for a selected group o…

Workload Characterization in Multiplayer Online Games

2006

In recent years, distributed virtual environments (DVEs) have become a major trend in distributed applications, mainly due to the enormous popularity of multiplayer online games in the entertainment industry. Although the workload generated by avatars in a DVE system has already been characterized, the special features of multiplayer online games make these applications to require a particular workload characterization. This paper presents the workload characterization of multiplayer online games. This characterization is based on real traces, and it shows that the movement patterns of avatars used to develop optimization techniques for DVE systems can be extrapolated to First Person Shooti…

Chapter 12. Multimodal measurement of cognitive load during subtitle processing

2018

Association between climate and new daily diagnoses of COVID-19

2020

AbstractBackgroundAlthough evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks, uncertainty remains concerning the real impact of climate factors on viral transmission. Methods. The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto Region, while information on daily weather parameters in the same area was downloaded from IlMeteo website, a renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 to November 11, 2020. The number of new daily COVID-19 cases and meteorological da…