Search results for "LOAD"

showing 10 items of 1967 documents

On the use of ionic liquids as mobile phase additives in high-performance liquid chromatography. A review.

2015

The popularity of ionic liquids (ILs) has grown during the last decades in several analytical separation techniques. Consequently, the number of reports devoted to the applications of ILs is still increasing. This review is focused on the use of ILs (mainly imidazolium-based associated to chloride and tetrafluoroborate) as mobile phase additives in high-performance liquid chromatography (HPLC). In this approach, ILs just function as salts, but keep several kinds of intermolecular interactions, which are useful for chromatographic separations. Both cation and anion can be adsorbed on the stationary phase, creating a bilayer. This gives rise to hydrophobic, electrostatic and other specific in…

TetrafluoroborateHETEROCYCLIC AROMATIC-AMINESBiochemistryHigh-performance liquid chromatographyChlorideAnalytical Chemistrychemistry.chemical_compoundSilanol suppressionAdsorptionSOLUBILIZING ABILITIES[CHIM.ANAL]Chemical Sciences/Analytical chemistryPhase (matter)medicineEnvironmental ChemistryOrganic chemistryOptimisationSpectroscopyHALF-WIDTH PLOTSMechanisms of retentionOVERLOADED BAND PROFILESANALYTICAL-CHEMISTRYSILANOL-SUPPRESSING POTENCYHYDROCARBONACEOUS STATIONARY PHASESIntermolecular forceAdditivesHigh-performance liquid chromatographyIonic liquidsSilanolROOM-TEMPERATURERETENTION MECHANISMChemical engineeringchemistryRP-HPLCIonic liquidmedicine.drugAnalytica chimica acta
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Rapid and eco-friendly synthesis of graphene oxide-silica nanohybrids

2014

The increasing interest in Graphene oxide (GO) is due to many issues: the presence of both sp2-conjugated atoms and oxygen-containing functional groups provides a strong hydrophilicity and the possibility to further functionalize it with other molecules (i.e. π-π interactions covalent attachment etc.) [1]. Furthermore since the GO is biocompatible and noncytotoxic many studies have been recently focused on the development of GO-based nanodevices for bioimaging DNA detection drug delivery. Due to their low cytotoxicity and large internal surface area silica nanoparticles have been taken into account as promising material for biolabeling and drug loading/delivery. Particular consideration has recently been demonstrated for GO-silica composites because of the potentialities for electrical applications their chemical inertia and stability toward ions exposure. The possibility to combine the extraordinary properties of GO and silica offers several advantages for the realization of nanoprobes for biological applications and of biosensor [12]. The strategy for the fabrication of GO-nanosilica nanohybrids can be schematized as follows: (i) synthesis of GO by oxidizing graphite powder with the method described by Marcano et al. [3] (ii) Preparation of oxygen-loaded silica nanoparticles by thermal treatments in controlled atmosphere in order to induce high NIR emission at 1272 nm from high purity silica nanoparticles. (iii) preparation of GrO-silica nanohybrid films via rapid solvent casting in water. The nanohybrids were tested by XPS FTIR Raman analysis UV photoluminescence analysis TGA Zeta potential measurements electrical tests AFM and SEM. Several nanohybrids were prepared by combining two different typologies of GO and two different samples of silica.
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Scavenger – A Framework for Efficient Evaluation of Dynamic and Modular Algorithms

2015

Machine Learning methods and algorithms are often highly modular in the sense that they rely on a large number of subalgorithms that are in principle interchangeable. For example, it is often possible to use various kinds of pre- and post-processing and various base classifiers or regressors as components of the same modular approach. We propose a framework, called Scavenger, that allows evaluating whole families of conceptually similar algorithms efficiently. The algorithms are represented as compositions, couplings and products of atomic subalgorithms. This allows partial results to be cached and shared between different instances of a modular algorithm, so that potentially expensive part…

Theoretical computer scienceBackupbusiness.industryComputer scienceDistributed computingCacheModular algorithmLoad balancing (computing)Modular designbusinessAlgorithm
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Parallel Collision Queries on the GPU

2013

We present parallel algorithms to accelerate collision tests of rigid body objects for a high number of independent transformations as they occur in sampling-based motion planning and path validation problems. We compare various GPU approaches with a different level of parallelism against each other and against a parallel CPU implementation. Our algorithms require no sophisticated load balancing schemes. They make no assumption on the distribution of the input transformations and require no pre-processing. Yet, we can perform up to 1 million collision tests per second with our best GPU implementation in our benchmarks. This is about 2.5X faster than our reference multi-core CPU implementati…

Theoretical computer scienceShared memoryComputer scienceParallel algorithmCollision detectionParallel computingMotion planningLoad balancing (computing)CollisionRigid bodyImplementation
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Three-dimensional analysis of load transfer micro-mechanisms in fibre/matrix composites

2009

International audience; This study gives a detailed analysis of load distributions around fibre breaks in a composite. In contrast to other studies reported in the literature, the analysis considers different configurations of composite damage from the failure of a few to the failure of many fibres. The model considers three types of matrix behaviours (elastic, elastic–plastic and viscoelastic) with or without debonding at the broken fibre/matrix interface. In this way, the usual limitations of the finite element approach are overcome so as to take into account the number and interactions of broken fibres whilst maintaining an evaluation of the various fields (stresses in particular).

Three dimensional analysisMaterials scienceFibre matrix interactionFinite element approachComposite number[ PHYS.COND.CM-MS ] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]General EngineeringDamage accumulation02 engineering and technologyUnidirectional composites021001 nanoscience & nanotechnologyViscoelasticityFinite element modellingMatrix (mathematics)020303 mechanical engineering & transports0203 mechanical engineeringDebondingLoad transferCeramics and Composites[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]Micro mechanismComposite material0210 nano-technology
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Barriers to insulin initiation and intensification and how to overcome them

2009

Summary Aims:  To review published evidence and clinical experience of the perceived barriers to insulin initiation and intensification and to develop solutions for patient management. Method:  Literature review and workshop discussions. Results:  Many patients with diabetes fail to achieve targets for glycaemic control because of inappropriate use of insulin. Patients and health care professionals face many potential barriers to insulin initiation and intensification in primary care. These can be categorised as low motivation, lack of familiarity or experience and time constraints. Conclusion:  Solutions should be tailored to different health care settings. Strategies include improving edu…

Time FactorsAttitude of Health Personnelmedicine.medical_treatmentMEDLINEPrimary careWorkloadPatient satisfactionNursingAcquired immunodeficiency syndrome (AIDS)Patient Education as TopicHealth caremedicineHumansHypoglycemic AgentsInsulinbusiness.industryInsulinWorkloadGeneral MedicineFearLow motivationmedicine.diseaseDiabetes Mellitus Type 2Patient SatisfactionbusinessFamily Practice
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The Effect of Different High-Intensity Periodization Models on Endurance Adaptations

2016

Purpose: This study aimed to compare the effects of three different high-intensity training (HIT) models, balanced for total load but differing in training plan progression, on endurance adaptations. Methods: Sixty-three cyclists (peak oxygen uptake (V˙O2peak) 61.3 ± 5.8 mL·kg−1·min−1) were randomized to three training groups and instructed to follow a 12-wk training program consisting of 24 interval sessions, a high volume of low-intensity training, and laboratory testing. The increasing HIT group (n = 23) performed interval training as 4 × 16 min in weeks 1–4, 4 × 8 min in weeks 5–8, and 4 × 4 min in weeks 9–12. The decreasing HIT group (n = 20) performed interval sessions in the opposite…

Time FactorsDownloadHigh intensityPhysical Therapy Sports Therapy and Rehabilitation030229 sport sciencesCreative commons030204 cardiovascular system & hematologyPermissionAdaptation PhysiologicalBicyclingBody Mass Index03 medical and health sciencesOxygen Consumption0302 clinical medicineWork (electrical)Multicenter studyPeriodizationPolitical scienceExercise TestPhysical EnduranceHumansOrthopedics and Sports MedicineLicensePhysical Conditioning HumanLaw and economics
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Comparison between hybrid moving bed biofilm reactor and activated sludge system: a pilot plant experiment

2010

The paper presents the comparison between the traditional activated sludge system (AS) and a hybrid moving bed biofilm reactor (HMBBR). In particular, an experimental campaign has been carried out at the WWTP in Palermo (Italy), on a pilot plant consisting of two pre-anoxic schemes. The aerated tank of the HMBBR line was filled with suspended carriers (AnoxKaldnes™ K1), with a 30% filling ratio. The hydraulic load of the HMBBR line was increased up to two times the AS one. Further, in order to distinguish the additional contribution of the attached biomass for the HMBBR system, in the two lines the Mixed Liquor Suspended Solids (MLSS) was maintained as equal as possible. The monitoring peri…

Time FactorsEnvironmental EngineeringNitrogenhybrid biofilm reactorPilot ProjectsHMBBRWaste Disposal Fluidmunicipal wastewaterWater PurificationBioreactorsorganic and nitrogen loadbiological treatmentOrganic ChemicalsWater Science and TechnologySettore ICAR/03 - Ingegneria Sanitaria-AmbientaleSewageMoving bed biofilm reactorSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaEnvironmental engineeringEquipment DesignnitrificationCarbonMixed liquor suspended solidsQuaternary Ammonium CompoundsWaste treatmentActivated sludgePilot plantItalyWastewaterBiofilmsEnvironmental scienceSewage treatmentWater Pollutants ChemicalWaste disposalWater Science and Technology
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Boceprevir is highly effective in treatment-experienced hepatitis C virus-positive genotype-1 menopausal women

2014

AIM: To investigate the safety/efficacy of Boceprevirbased triple therapy in hepatitis C virus (HCV)-G1 menopausal women who were historic relapsers, partial-responders and null-responders. METHODS: In this single-assignment, unblinded study, we treated fifty-six menopausal women with HCV-G1, 46% F3-F4, and previous PEG-α/RBV failure (7% null, 41% non-responder, and 52% relapser) with 4 wk lead-in with PEG-IFNα2b/RBV followed by PEGIFNα2b/RBV+Boceprevir for 32 wk, with an additional 12 wk of PEG-IFN-α-2b/RBV if patients were HCV-RNA-positive by week 8. In previous null-responders, 44 wk of triple therapy was used. The primary objective of retreatment was to verify whether a sustained virolo…

Time FactorsViral HepatitisClinical Trials StudyHepacivirusViral hepatitiPolyethylene GlycolPolyethylene Glycolschemistry.chemical_compoundPegylated interferonOdds RatioMultivariate AnalysiPegylated InterferonGastroenterologyGeneral MedicineHepatitis CHepatitis c virus treatmentMiddle AgedRecombinant ProteinViral LoadGenotype 1Recombinant ProteinsMenopauseTreatment OutcomeItalyRNA ViralDrug Therapy CombinationFemaleMenopauseViral hepatitisViral loadPegylated interferonHumanmedicine.drugmedicine.medical_specialtyGenotypeLogistic ModelProlineTime FactorInterferon alpha-2Hepatitis C virus treatmentAntiviral AgentsPharmacotherapyInternal medicineBoceprevirRibavirinmental disordersmedicineHumansAntiviral AgentHepacivirubusiness.industryInterferon-alphaBiomarkerGenotype 1; Hepatitis c virus treatment; Menopause; Pegylated interferon; Viral hepatitis; Antiviral Agents; Biomarkers; Drug Therapy Combination; Female; Genotype; Hepacivirus; Hepatitis C Chronic; Humans; Interferon-alpha; Italy; Logistic Models; Middle Aged; Multivariate Analysis; Odds Ratio; Polyethylene Glycols; Proline; RNA Viral; Recombinant Proteins; Ribavirin; Time Factors; Treatment Outcome; Viral Load; Menopause; GastroenterologyHepatitis C Chronicmedicine.diseaseVirologyLogistic ModelschemistryHepatitis C Virus PositiveMultivariate AnalysisGenotype 1; Hepatitis C virus treatment; Menopause; Pegylated Interferon; Viral HepatitisbusinessBiomarkers
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Customized Titanium Lattice Structure in Three-Dimensional Alveolar Defect: An Initial Case Letter

2018

The aim of this initial case report was to provide a new protocol for the clinical application of a patient-specific titanium lattice structure (Yxoss CBR®, ReOSS, Filderstadt, Germany) for customized bone regeneration. To obtain a 3-dimensional reconstruction of a posterior mandible segment in a 61-year-old woman, a patient-specific titanium customized lattice structure was used. As graft material autogenous bone tissue mixed with xenogenic alloplastic material (Bio Oss®, Geistlich Pharma, Wolhusen, Switzerland) was obtained for reconstruction. After a healing period of 6 months, the titanium lattice structure was removed and implant placement (Camlog Screw Line, 3.8/11, Camlog, Wimsheim, …

TitaniumPosterior mandibleMaterials scienceBone specimenchemistry.chemical_elementAlveolar Ridge Augmentation030206 dentistryCrystal structureAlveolar Ridge AugmentationImplant placement03 medical and health sciences0302 clinical medicinechemistry030220 oncology & carcinogenesisComputer-Aided DesignImplant loadingOral SurgeryBone regenerationTitaniumBiomedical engineeringJournal of Oral Implantology
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