Search results for "LOAD"

Impact of body weight on virological and immunological responses to efavirenz-containing regimens in HIV-infected, treatment-naive adults

2015

Objective: The prevalence of overweight and obesity is increasing among HIV-infected patients. Whether standard antiretroviral drug dosage is adequate in heavy individuals remains unresolved. We assessed the virological and immunological responses to initial efavirenz (EFV)-containing regimens in heavy compared to normal-weight HIV-infected patients. Design: Observational European cohort collaboration study. Methods: Eligible patients were antiretroviral-naive with documented weight prior to EFV start and follow-up viral loads after treatment initiation. Cox regression analyses evaluated the association between weight and time to first undetectable viral load ( 50 copies/ml) after initial s…

Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells.

2013

Respiratory syncytial virus (RSV) causes acute exacerbations in COPD and asthma. RSV infects bronchial epithelial cells (HBE) that trigger RSV associated lung pathology. This study explores whether the phosphodiesterase 4 (PDE4) inhibitor Roflumilast N-oxide (RNO), alters RSV infection of well-differentiated HBE (WD-HBE) in vitro. WD-HBE were RSV infected in the presence or absence of RNO (0.1-100 nM). Viral infection (staining of F and G proteins, nucleoprotein RNA level), mRNA of ICAM-1, ciliated cell markers (digital high speed videomicroscopy, β-tubulin immunofluorescence, Foxj1 and Dnai2 mRNA), Goblet cells (PAS), mRNA of MUC5AC and CLCA1, mRNA and protein level of IL-13, IL-6, IL-8, T…

El coneixement i l'ús de les aplicacions educatives dels estudiants universitaris d'Espanya i la República Txeca

2020

Technological evolution has led to many changes at both professional and academic levels. The inclusion of Information and Communication Technologies (ICT) has caused dizzying changes in the different contexts of life (educational, professional, social). More and more applications are being downloaded by users to their mobile devices, both for entertainment and training. For this reason, this study is based on the need to assess the knowledge and attitude of university students towards downloading existing educational applications. In this way, the use and frequency of these tools in the teaching-learning process of the students will be analyzed. In order to carry out this study, the quanti…

An integral equation for damage identification of Euler-Bernulli beams under static loads

2004

A Strain Sensing Structural Health Monitoring System for Delaminated Composite Structures

2012

Structural Health Monitoring (SHM) for composite materials is becoming a primary task due to their extended use in safety critical applications. Different methods, based on the use of piezoelectric transducers as well as of fiber optics, has been successfully proposed to detect and monitor damage in composite structural components with particular attention focused on delamination cracks.In the present paper a Structural Health Monitoring model, based on the use of piezoelectric sensors, already proposed by the authors for isotropic damaged components, is extended to delaminated composite structures. The dynamic behavior of the host damaged structure and the bonded piezoelectric sensors is m…

Noise reduction in asteroid imaging using a miniaturized spectral imager

2021

In October 2024, European Space Agency’s Hera mission will be launched, targeting the binary asteroid Didymos. Hera will host the Juventas and Milani CubeSats, the first CubeSats to orbit close to a small celestial body performing scientific and technological operations. The primary scientific payload of the Milani CubeSat is the SWIR, NIR, and VIS imaging spectrometer ASPECT. The Milani mission objectives include mapping the global composition and the characterization of the binary asteroid surface. Onboard data processing and evaluation steps will be applied due to the limited data budget for the downlink to Earth and to perform the technological demonstration of a novel semi-autonomous h…

Migration Techniques in HPC Environments

2014

Process migration is an important feature in modern computing centers as it allows for a more efficient use and maintenance of hardware. Especially in virtualized infrastructures it is successfully exploited by schemes for load balancing and energy efficiency. One can divide the tools and techniques into three groups: Process-level migration, virtual machine migration, and container-based migration.

Electricity demand management by optimising the use of HVAC and HWS through AMI

2017

The consumption of electricity is increasing with consistent increase in demand of electricity. Advance metering infrastructure (AMI) is a part of energy management system (EMS) that can pro-actively control the consumption of electricity by engaging with utilities for demand management in real-time. The analysis of the electricity consumption pattern of an Australian house is conducted in this study. The investigation reveals that Heat Ventilation Air conditioning (HVAC) and Hot Water System (HWS) consume approximately 50% of the total electricity consumption. Optimised utilization of these two systems efficiently using AMI can help in reduction of electricity consumption. The study also i…

On the effects of BAC systems and load control programs on the utility grid

2017

The electricity demand increasing for the comfort improvement in residential buildings is nowadays stressing the MV and LV networks in urban areas. In this framework, the Distribution System Operators (DSO) are exposed to the risk of reliability decrease and there is, earlier than expected, the issue of new and substantial investments for enhancing the network infrastructure. Nevertheless, DSOs have a very strong inclination to defer investment in new facilities in favour of more "flexible measures" for improving the life of the existing components. Solutions of this type are primarily based on demand management, i.e. activities aimed at encouraging the end-users to a different/smart electr…

Impact of Demand Response Control Logic on Isolated Island's Distribution Networks

2019

The work presents the results of a study regarding the impact of some Demand Response control logics on an isolated distribution network. The proposed control is divided into precise steps in which the coordination between the general aggregator controller and the single local Energy Management Systems is developed and illustrated with details. The control is applied to the flexible loads and to the storage systems of photovoltaic plants installed at the end-users' houses and connected to the network. The study is carried out delivering a suitable network model of the island's system, with the implementation of load profiles for all the loads of the network for a total simulation time of 24…