Search results for "LOCATIONS"

showing 10 items of 301 documents

Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines.

2013

J. Balmana1, F. Balaguer2, A. Cervantes3 & D. Arnold4, on behalf of the ESMO Guidelines Working Group* Department of Medical Oncology, Hospital Vall d’Hebron, Vall d’Hebron Institute of Oncology (VHIO), Universitat Autonoma de Barcelona, Barcelona; Department of Gastroenterology, Hospital Clinic, CIBERehd, IDIBAPS, University of Barcelona, Barcelona; Department of Hematology and Medical Oncology, INCLIVA, University of Valencia, Valencia, Spain; Department of Medical Oncology, Tumor Biology Clinic, Albert Ludwigs University, Freiburg, Germany;

Riskmedicine.medical_specialtyColorectal cancerChemopreventionDNA Mismatch RepairDNA GlycosylasesNeoplastic Syndromes Hereditaryhealth services administrationMedicineHumansGenetic Predisposition to DiseaseGenetic TestingMultiple PolypsSigmoidoscopyEarly Detection of CancerAgedTumor biologybusiness.industryBrain NeoplasmsGeneral surgeryHematologyColonoscopyFamilial riskMiddle Agedmedicine.diseaseColorectal Neoplasms Hereditary NonpolyposishumanitiesClinical PracticeEuropeOncologyAdenomatous Polyposis Colipopulation characteristicsFemaleMicrosatellite InstabilitybusinessColorectal NeoplasmsColorectal Surgerygeographic locationsAnnals of oncology : official journal of the European Society for Medical Oncology
researchProduct

Flash-Floods Influence Macroinvertebrate Communities Distribution in Lotic Ecosystems

2019

Abstract Stream dwelling invertebrate populations are facing an ample array of stressors including the habitat imbalance caused by important floods. In this research we used a novel way to estimate the impact of floods upon the substrate, by utilising a remote variable named “flash-flood potential” (FFP), which accounts for the site slope and the average slope of the upstream catchment. The results showed that certain groups are sensitive to the influence of the FFP whereas other are not. We propose this remote variable as a surrogate for assessing stress imposed by floods and sediment scouring for lotic macroinvertebrates.

River ecosystemDrainage basinDistribution (economics)ecological indicatorsparasitic diseasesFlash floodQH540-549.5InvertebrateHydrologygeographygeography.geographical_feature_categoryEcologybusiness.industryfungiSedimentfood and beveragesflash flood potentialSubstrate (marine biology)populations ecologycatchment slopeHabitatEnvironmental sciencepopulation characteristicshabitat fragmentationbusinessgeographic locationsTransylvanian Review of Systematical and Ecological Research
researchProduct

Valodu centru mājaslapu analīze

2018

Šajā darbā uzmanība tiek veltīta galvenokārt Humanitāro zinātņu fakultātes Lietišķās valodniecības centra (LVC) apakšvietnes satura analīzei. Darba mērķis ir noteikt LVC mājaslapas semantiskos kodolus un pārbaudīt vietnes atslēgvārdu un atslēgu vārdkopu saderību Google meklētājprogrammā. Analīze tika veikta ar moderno Google rīku palīdzību un manuāli atpazīstot pašreizējos atslēgvārdus un atslēgu vārdkopas tīmekļa vietnes lapās. Šis pētījums uzsver semantiskā kodola sagatavošanas nozīmi pirms mājaslapas izstrādāšanas, kā arī to, kā ik pa laikam var pārbaudīt atslēgvārdu un atslēgu vārdkopu saderību (Google atpazīšanu). Empīriskais pētījums tika īstenots izmantojot kvalitatīvo un kvantitatīv…

SEOkey-collocationskey-wordsValodniecībasemantic corewebsite content
researchProduct

Ethics appraisal procedure in 79,670 Marie Skłodowska-Curie proposals from the entire European HORIZON 2020 research and innovation program (2014–202…

2021

Introduction Horizon 2020 was the most significant EU Research and Innovation programme ever implemented and included the Marie Skłodowska-Curie Actions (MSCA). Proposals submitted to the MSCA actions awere subject to the Ethics Appraisal Procedure. In this work we explored the ethics appraisal procedure in MSCA H2020. Methods Using a retrospective analysis of pooled anonymized data, we explored the ethics appraisal procedure on proposals submitted to Marie Skłodowska-Curie Actions (MSCA) during the entire Horizon 2020 program period (N = 79,670). Results Our results showed that one of the most frequently identified ethics categories was Data protection. We also detected slight differences…

Science and Technology WorkforceScience PolicyScienceLegislationPublication EthicsSocial SciencesCareers in ResearchResearch EthicsGeographical locationsEthics ResearchInformed consentData AnonymizationMedicine and Health SciencesCurieRetrospective analysisData Protection Act 1998Public and Occupational HealthEuropean UnionCell Cycle and Cell DivisionResearch IntegrityRetrospective StudiesMedical educationResearch ethicsMultidisciplinaryHorizon (archaeology)QMSCA H2020 Ethics appraisal procedure research integrityRBiology and Life SciencesSubject (documents)Cell BiologyEuropeHealth CareWork (electrical)Cell ProcessesMedicineLaw and Legal SciencesPeople and placesPsychologyEnvironmental HealthResearch ArticlePLOS ONE
researchProduct

Contribution of planktonic and benthic food sources to the diet of the reef-forming vermetid gastropod Dendropoma petraeum in the western Mediterrane…

2012

Abstract In the Mediterranean Sea, the vermetid Dendropoma petraeum (Monterosato, 1884) forms highly biodiverse reefs that have received increasing attention in recent years although very little is known about the food habit of this species. The main goal of this study was to describe the trophic role of planktonic and benthic food sources for D. petraeum . Specimens from three morphological zones of the reef (inner edge, cuvette and outer edge) at two sites with different wave exposure along the north-western coast of Sicily (Italy; western Mediterranean) were compared for δ 13 C and δ 15 N. Isotopic determinations were also carried out on potential food sources identified in epilithon, re…

Settore BIO/07 - EcologiaMediterranean climateDendropoma petraeumgeographygeography.geographical_feature_categorybiologyEcologyfungiIntertidal zoneAquatic SciencePlanktonOceanographybiology.organism_classificationVermetidae stable isotopes intertidal food habit wave exposure mixing modelOceanographyMediterranean seaBenthic zoneReefgeographic locationsTrophic levelEstuarine, Coastal and Shelf Science
researchProduct

MANSIONI E DEROGABILITÁ INDIVIDUALE ASSISTITA

2018

Il saggio analizza l'istituto della derogabilità individuale assistita delle mansioni per come configurato dal d.lgs. 81/2015: tale norma, nel consentire accordi tra lavoratore e datore modificativi di mansioni, retribuzione, livello di inquadramento e categoria legale, depone a favore di una marcata liberalizzazione dell’oggetto del contratto di lavoro. I limiti dettati dalla legge – la stipula innanzi a delle sedi protette e il ricorrere di generiche finalità – contribuiscono a creare uno scenario "fluido" di tutela del lavoratore quale contraente debole, non soltanto all'atto della sottoscrizione del patto, ma anche in sede processuale. The essay focuses on the mechanism of the individua…

Settore IUS/07 - Diritto Del LavoroMansioni – derogabilità individuale – sedi protette – liberalizzazione – Jobs Act.Worker’s duties – individual derogability – protected locations – liberalisation – Jobs Act.
researchProduct

Efficacy of a 12-Week Simeprevir Plus Peginterferon/Ribavirin (PR) Regimen in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 4 (GT4) …

2017

Background HCV GT4 accounts for up to 20% of HCV infections worldwide. Simeprevir, given for 12 weeks as part of a 24- or 48-week combination regimen with PR is approved for the treatment of chronic HCV GT4 infection. Primary study objectives were assessment of efficacy and safety of simeprevir plus PR in treatment-naïve patients with HCV GT4 treated for 12 weeks. Primary efficacy outcome was sustained virologic response 12 weeks post-treatment (SVR12). Additional objectives included investigation of potential associations of rapid virologic response and baseline factors with SVR12. Methods This multicentre, open-label, single-arm study (NCT01846832) evaluated efficacy and safety of simepre…

SimeprevirMalePsychologie appliquéeFetge - MalaltiesHepacivirusGastroenterologyPolyethylene GlycolPolyethylene Glycols0302 clinical medicinelcsh:Science61 - MedicinaLiver DiseasesSciences bio-médicales et agricolesCirrhosisInterferonLiver Fibrosis030211 gastroenterology & hepatologyDrug Therapy CombinationViral loadBiologieHumanmedicine.medical_specialtyCiències multidisciplinàriesGenotypeSaudi ArabiaAlpha interferon:Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]Gastroenterology and HepatologyMicrobiologyAntiviral Agents03 medical and health sciencesHumansAgedMedicine and health sciencesHepaciviruFlavivirusesInterleukinslcsh:ROrganismsInterleukinmedicine.diseaseRegimen:Digestive System Diseases::Liver Diseases [DISEASES]chemistryImmunologylcsh:QMedicaments - AdministracióDevelopmental BiologyRNA viruseslcsh:Medicinemedicine.disease_cause:Other subheadings::Other subheadings::/drug therapy [Other subheadings]Geographical Locationschemistry.chemical_compoundSimeprevirHospital Universitari Vall d’Hebron030212 general & internal medicinePathology and laboratory medicineMultidisciplinaryHepatitis C virusHepatitis CRecombinant ProteinMedical microbiologyMiddle AgedViral LoadHepatitis CRecombinant Proteins:enfermedades del sistema digestivo::enfermedades hepáticas [ENFERMEDADES]EuropeResearch DesignVirusesFemalePathogensResearch ArticleAdultAsiaAdolescentClinical Research DesignHepatitis C virusResearch and Analysis MethodsYoung AdultInternal medicineRibavirinmedicineddc:610Rapid Virologic ResponseAntiviral AgentBiology and life sciencesbusiness.industryRibavirinViral pathogensInterferon-alphaFibrosisHepatitis virusesMicrobial pathogensPeople and PlacesAdverse EventsInterferonsbusinessPLoS ONE
researchProduct

Large-scale effects of migration and conflict in pre-agricultural groups: Insights from a dynamic model.

2016

The debate on the causes of conflict in human societies has deep roots. In particular, the extent of conflict in hunter-gatherer groups remains unclear. Some authors suggest that large-scale violence only arose with the spreading of agriculture and the building of complex societies. To shed light on this issue, we developed a model based on operatorial techniques simulating population-resource dynamics within a two-dimensional lattice, with humans and natural resources interacting in each cell of the lattice. The model outcomes under different conditions were compared with recently available demographic data for prehistoric South America. Only under conditions that include migration among c…

Social ProblemsEcological MetricsMolecular biologyPopulation Dynamicslcsh:MedicineDNA constructionGeographical locationsPopulation dynamics Heisenberg equation quantum dynamicsPopulation MetricsNatural ResourcesGene Expression and Vector TechniquesHumanslcsh:ScienceSettore MAT/07 - Fisica MatematicaDemographyPopulation DensityMolecular Biology Assays and Analysis TechniquesPopulation BiologyEcologyEcology and Environmental Scienceslcsh:RBiology and Life SciencesAgricultureVector ConstructionEmigration and ImmigrationModels TheoreticalSouth AmericaResearch and analysis methodsMolecular biology techniquesSocioeconomic FactorsCarrying Capacitylcsh:QPeople and placesAlgorithmsResearch ArticlePLoS ONE
researchProduct

Balanced difficulty task finder: an adaptive recommendation method for learning tasks based on the concept of state of flow

2020

An adaptive task difficulty assignment method which we reckon as balanced difficulty task finder (BDTF) is proposed in this paper. The aim is to recommend tasks to a learner using a trade-off between skills of the learner and difficulty of the tasks such that the learner experiences a state of flow during the learning. Flow is a mental state that psychologists refer to when someone is completely immersed in an activity. Flow state is a multidisciplinary field of research and has been studied not only in psychology, but also neuroscience, education, sport, and games. The idea behind this paper is to try to achieve a flow state in a similar way as Elo’s chess skill rating (Glickman in Am Ches…

Stochastic point locationComputer scienceCognitive NeuroscienceGame ranking systemsAnalogyIntelligent tutoring system02 engineering and technologyField (computer science)Intelligent tutoring systemAdjusting delayed matching-to-sampleTask (project management)03 medical and health sciences0302 clinical medicineHuman–computer interaction0202 electrical engineering electronic engineering information engineeringStochastic point locationsVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550State of flowTrueSkillSpaced retrievalComputerized adaptive testingComputingMilieux_PERSONALCOMPUTINGIntelligent tutoring systemsOnline learning020201 artificial intelligence & image processingComputerized adaptive testingState (computer science)Adaptive task difficulties030217 neurology & neurosurgeryResearch ArticleAdaptive task difficultyCognitive Neurodynamics
researchProduct

Use of Different Food Classification Systems to Assess the Association between Ultra-Processed Food Consumption and Cardiometabolic Health in an Elde…

2021

The PREDIMED-Plus trial was supported by the European Research Council (Advanced Research grant 2014–2019; agreement #340918; granted to M.Á.M.-G.); the official Spanish institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII) through the Fondo de Investigación para la Salud (FIS) which is co-funded by the European Regional Development Fund (coordinated FIS projects led by J.S-S. and J.V., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI…

Síndrome metabólicoMaleFood processingMediterranean dietNOVAObesidadÍndice de masa corporal:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineultra-processed foodMedicineTX341-641:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight [Medical Subject Headings]Body mass indexclassification systemsIncidenceIARC:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings]Metabolic syndrome3. Good healthNutriciónCohortManipulación de alimentosDietaFactores de riesgo cardiometabólicoConcordanceUNC:Check Tags::Male [Medical Subject Headings]ClasificaciónClassification systemsDiet SurveysArticle03 medical and health sciencesfood processingHumans:Diseases::Cardiovascular Diseases [Medical Subject Headings]Aged030109 nutrition & dietetics:Health Care::Health Care Economics and Organizations::Organizations::International Agencies [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesity:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Blood pressure:Check Tags::Female [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Linear ModelsFast FoodsMetabolic syndromeOlder people0301 basic medicineSíndrome metabòlicaFood HandlingOverweightDiet MediterraneanPersones gransCohort Studiescardiometabolic riskEndocrinología030212 general & internal medicine:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerMetabolic SyndromeNutrition and Dietetics:Technology and Food and Beverages::Technology Industry and Agriculture::Industry::Food Industry::Food Handling [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Nutrition Surveys::Diet Surveys [Medical Subject Headings]Female:Technology and Food and Beverages::Food and Beverages::Food::Fast Foods [Medical Subject Headings]medicine.symptom:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance::Metabolic Syndrome X [Medical Subject Headings]Dietética y nutrición:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence [Medical Subject Headings]Environmental healthMediterranean dietObesityAlimentos ultraprocesados:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Linear Models [Medical Subject Headings]NutricióNutrition:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryNutrition. Foods and food supplyCardiometabolic Risk FactorsOverweightDieta mediterráneaCardiometabolic riskUltra-processed foodDietSpainIFICSobrepesoFood processingbusinessdietFood ScienceNutrients
researchProduct