Search results for "LOCI"

Modelling of the Ischemic Penumbra

1999

What happens to the ischemic penumbra – defined as a territory of critically reduced blood flow in the close neighborhood of an ischemic core – determines outcome after stroke. Currently the pathophysiology of the penumbra is studied predominantly in rat models with occlusion of the middle cerebral artery. Here we propose two other rat models with distinct advantages. One produces a large territory of critical flow reduction in the cortex of one hemisphere without presence of an infarct core: this model is suited to study mediator mechanisms that may transform the penumbra into necrotic tissue. It is produced by occluding one carotid artery and in addition reducing arterial pressure to 50mm…

Duplexsonographie abdomineller Gefäße

1987

Duplex sonography is a non-invasive procedure which permits the determination of flow velocity and direction in visceral vessels. Results in 50 normals have shown that small arteries can be evaluated in about 50% of cases. The portal venous system can be demonstrated in all cases; average flow velocity and volume is 15.2 +/- 2.8 cm/s and 694 +/- 230 ml/min, corresponding with the values obtained by invasive methods. Clinical application for duplex examinations can be found in portal hypertension, varices, thromboses, aneurysms and transplant kidneys.

Comparison Between Influence Of The Conduction Velocity And the Refractory Period Variations On The Reentry Mechanism

2005

1043 Evaluation of Pediatric Testes After Surgery by Laser Doppler and White Light Spectroscopy

2012

Aim To evaluate testes after unilateral orchiopexy Laser Doppler and white light spectroscopy and compare microcirculation with contralaterat testis and healthy controls. Methods A combination of the laser Doppler (determination of blood flow) and white light spectroscopy (determination of oxygen saturation and hemoglobin amount) is used to determine microcirculation at two different depth levels non-invasively. Patients were recruited after unilateral orchiopexy. Controls were age-matched boys without relevant disease. Ethical approval was obtained. Results 99 patients were included after unilateral orchiopexy at the age of 3.5 years (+-2.9 years). 65% underwent surgery after their second …

FRI0662 ACTIVATION AND LEUKOCYTE ADHESION IS ASSOCIATED WITH VASCULAR DAMAGE IN PATIENTS WITH RHEUMATOID ARTHRITIS AND PSORIATIC ARTHRITIS

2019

Background Patients with inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) or psoriatic arthritis (PsA), have a higher cardiovascular risk than the general population. There are data in other pathologies about the role of leukocyte adhesion on endothelial damage. Objectives To evaluate the relationship between leukocyte adhesion and subclinical vascular damage in patients with RA and PsA. Methods Observational, cross-sectional exploratory study. Patients with RA and PsA who had at least one previous vascular study were recruited in a tertiary hospital during a period of 3 months. All of them donated a sample of fresh blood. Neutrophils were isolated and perfused on a monola…

Transient hypothyroidism during lactation arrests myelination in the anterior commissure of rats. A magnetic resonance image and electron microscope …

2018

Thyroid hormone deficiency at early postnatal ages affects the cytoarchitecture and function of neocortical and telencephalic limbic areas, leading to impaired associative memory and in a wide spectrum of neurological and mental diseases. Neocortical areas project interhemispheric axons mostly through the corpus callosum and to a lesser extent through the anterior commissure (AC), while limbic areas mostly project through the AC and hippocampal commissures. Functional magnetic resonance data from children with late diagnosed congenital hypothyroidism and abnormal verbal memory processing, suggest altered ipsilateral and contralateral telencephalic connections. Gestational hypothyroidism aff…

Leg extension power asymmetry and mobility limitation in healthy older women

2005

Objective To investigate the association of asymmetry in leg extension power (LEP) with walking and standing balance. Design Cross-sectional analysis. Setting Research laboratory. Participants Healthy female twins (N=419), ages 63 to 75 years. Interventions Not applicable. Main Outcome Measures The LEP difference between the stronger and the weaker leg, measured with the Nottingham power rig, was calculated. Ten-meter maximal walking velocity was assessed in a laboratory corridor on a wide (170cm) and narrow (35cm) track, and the ability to maintain tandem stance for 20 seconds was recorded. Results The mean LEP difference ± standard deviation between the legs was 15%±9% (P<.001). Those wit…

Muscle conduction velocity, strength, neural activity, and morphological changes after eccentric and concentric training

2014

This study compared the effects of concentric and eccentric training on neuromuscular adaptations in young subjects. Twenty-two men and women were assigned to one of two groups: concentric (CON, n = 11) and eccentric (ECC, n = 11) training. Training consisted of 6 weeks of isokinetic exercise, performed twice weekly, starting with two sets of eight repetitions, and progressing to five sets of 10 repetitions. Subjects were tested in strength variables [concentric, eccentric, and isometric peak torque (PT), and rate of force development (RFD)], muscle conduction velocity (CV), neuromuscular activity, vastus lateralis (VL) muscle thickness, and echo intensity as determined by ultrasonography. …

Myoedema

1992

Stationary muscle mounding after muscle percussion without electrical muscle activity is called myoedema. Out of 105 patients with different neurological diseases, 88% had this phenomenon. Muscle conduction velocity and stimulated single fiber EMG disclosed no abnormalities. Myoedema is a normal physiological phenomenon, and its presence does not indicate a neuromuscular disorder.

Psicologia de la Memòria. Quadern de Pràctiques

2014

El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València. El cuaderno de prácticas de Psicología de la Memoria tiene como objetivos ilustrar a partir de ocho actividades, dirigidas y prácticas, algunos de los principales fundamentos teóricos de la Psicología de la Memoria, y ayudar a los estudiantes a familiarizarse con los procedimientos utilizados en la investigación básica de esta disciplina. En la 1ª actividad, se invita al alumno a reflexionar en torno al concepto de memoria y su complejidad y se complementa con una propuesta de trabajo con una de las pruebas conductuales utilizadas actualmente para la e…