Search results for "LONG"
showing 10 items of 3969 documents
Long-term results of fascial sling procedure
1993
In a retrospective study 108 patients (average age: 56.5 years) could be evaluated, who were treated with a fascial sling plasty because of pure genuine stress incontinence (n=90) or combined stress/urge incontinence (n=18). 72 patients (66.6%) had recurrent incontinence after previous surgery. The average follow-up was 5 years.
Ten-year follow-up on efficacy, immunogenicity and safety of two doses of a combined measles-mumps-rubella-varicella vaccine or one dose of monovalen…
2020
Abstract Background We assessed the 10-year efficacy, immunogenicity and safety of two doses of a combined measles-mumps-rubella-varicella vaccine (MMRV) or one dose of a monovalent varicella vaccine (V) in children from Czech Republic, Lithuania, Poland, Romania and Slovakia. Methods This was a phase IIIB follow-up of an observer-blind, randomized, controlled trial (NCT00226499). In phase A, healthy children aged 12–22 months from 10 European countries were randomized in a 3:3:1 ratio to receive two doses of MMRV (MMRV group), one dose of MMR followed by one dose of V (MMR + V group), or two doses of MMR (MMR; control group), 42 days apart. Vaccine efficacy (VE) against varicella (confirme…
Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer
2021
Given the lack of effective treatments for Hepatocellular carcinoma (HCC), the development of novel therapeutic approaches is very urgent. Here, siRNAs were delivered to HCC cells by a synthetic polymer containing α,β-poly-(N-2-hydroxyethyl)-D,L-aspartamide-(PHEA) derivatized with diethylene triamine (DETA) and bearing in the side chain galactose (GAL) linked via a polyethylene glycol (PEG) to obtain (PHEA-DETA-PEG-GAL, PDPG). The GAL residue allows the targeting to the asialo-glycoprotein receptor (ASGPR), overexpressed in HCC cells compared to normal hepatocytes. Uptake studies performed using a model siRNA or a siRNA targeted against the enhanced green fluorescence protein, demonstrated …
Self-Efficacy, Planning, or a Combination of Both? A Longitudinal Experimental Study Comparing Effects of Three Interventions on Adolescents’ Body Fat
2016
Author(s): Luszczynska, Aleksandra; Hagger, Martin S; Banik, Anna; Horodyska, Karolina; Knoll, Nina; Scholz, Urte | Abstract: BackgroundThe superiority of an intervention combining two sets of theory-based behavior change techniques targeting planning and self-efficacy over an intervention targeting planning only or self-efficacy only has rarely been investigated.PurposeWe compared the influence of self-efficacy, planning, and self-efficacy+planning interventions with an education-based control condition on adolescents' body fat, assuming mediating effects of respective social cognitive variables and moderate-to-vigorous physical activity (MVPA). The moderating role of the built environment…
L’avvio della ricerca empirica in campo educativo in Italia: il contributo di Calonghi e Visalberghi
2014
Mentre la filosofia dominante in Italia alla fine della seconda guerra mondiale non era favorevole alla sperimentazione pedagogica, alcune iniziative, tese a innovare in senso attivistico i contenuti e i metodi dell’insegnamento scolastico, costituirono le cause remote dell’avvio dello studio dell’educazione con il metodo positivo. Esse facilitarono l’azione dei pionieri della ricerca empirica in campo educativo, che si sviluppò in Italia a partire dagli anni cinquanta del XX secolo per tre cause prossime: l’influsso delle sperimentazioni realizzate nelle scuole degli USA, la diffusione del pensiero di Dewey, l’impulso dato dall’Istituto Superiore di Pedagogia dei Salesiani allo studio dell…
Development of math anxiety and its longitudinal relationships with arithmetic achievement among primary school children
2019
Abstract The aim of this study is to examine the development of two separable aspects of math anxiety, anxiety about math-related situations and anxiety about failure in math, and their cross-lagged relationship with arithmetic achievement. The mean level of anxiety about math-related situations decreased among second, third, and fourth graders, and the level of anxiety about failure in math declined among third, fourth, and fifth graders. The rank-order of individuals was more stable in arithmetic achievement than in either aspect of math anxiety. Arithmetic achievement predicted later anxiety about failure in math, but neither aspect of math anxiety predicted later achievement. The result…
Young children in day and night care : negotiating and constructing belonging during daily arrivals
2016
The paper aims at understanding the processes related to young children's belonging during daily arrivals at day and night care. Two aspects of a child's belonging are considered: membership and sense of belonging. Data were gathered by ethnographic observation of 8 children aged from 20 to 36 months in two Finnish day care centres offering day and night care. Arrival episodes taking place at different times of day were analysed qualitatively based on the children's actions and expressions. During these episodes, the children negotiated and constructed their belonging by interacting with adults, peers and material objects. These interactions took place within varying social and material sur…
Early cognitive predictors of PISA reading in children with and without family risk for dyslexia
2018
Abstract This study examined language skills and pre-literacy skills (phonological awareness, rapid naming, and letter knowledge) before school-age as predictors of PISA reading at age 15 in two groups of children, with (n = 88) and without (n = 70) family-risk for dyslexia . Moreover, effects of family-risk on these early predictors, reading fluency , and PISA reading were examined while controlling the effect of gender. Children were followed from age 2 to 15. Family-risk had a significant effect on early language and pre-literacy skills, reading fluency and PISA reading. A similar model predicting PISA reading fitted the data well in the Family-risk and the No family-risk group. Languag…
A Comparison of Dyadic and Social Network Assessments of Peer Influence.
2021
The present study compares two methods for assessing peer influence: the longitudinal actor–partner interdependence model (L-APIM) and the longitudinal social network analysis (L-SNA) Model. The data were drawn from 1,995 (49% girls and 51% boys) third grade students ( Mage= 9.68 years). From this sample, L-APIM ( n = 206 indistinguishable dyads and n = 187 distinguishable dyads) and L-SNA ( n = 1,024 total network members) subsamples were created. Students completed peer nominations and objective assessments of mathematical reasoning in the spring of the third and fourth grades. Patterns of statistical significance differed across analyses. Stable distinguishable and indistinguishable L-AP…
The Role of Information and Communication Technologies in the Relationship Between Group Effectiveness and Group Potency
2008
The aim of this research is to examine the role of information and communication technologies in the relationship between group effectiveness and group potency changes. A laboratory experiment compared 44 groups of four members, working in two communication media—face-to-face condition and computer-mediated communication (CMC). Groups developed a project during 4 weekly meetings during a 1-month period. No significant difference in group potency between communication media was found initially. However, different patterns of group potency development over time were identified. Group potency increased in the face-to-face condition, whereas it remained stable in the CMC condition. Results sho…