Search results for "LR"

showing 10 items of 764 documents

Valoración del estado periodontal, perfil inflamatorio y disfunción endotelial en pacientes con Síndrome de Ovario Poliquístico

2022

Las enfermedades periodontales (PDs [del inglés, Periodontal Diseases]) son unas de las enfermedades más frecuentes. Estas patologías, son infecciosas - causadas por bacterias- y su naturaleza de inflamación crónica las ha relacionado con múltiples enfermedades sistémicas. Recientemente, se ha planteado la asociación de las PDs con el Síndrome de Ovario Poliquístico (PCOS [del inglés, Polycistic Ovary Syndrome]). Este síndrome, es un trastorno endocrino complejo cuyo criterio diagnóstico según el Consenso de Róterdam, contempla la presencia de oligo y/o anovulación, signos clínicos y/o bioquímicos de hiperandrogenismo y ovarios de apariencia ecográfica poliquística. La estimulación y secrec…

activación del inflamasoma nlrp3síndrome de ovario poliquísticogingivitis en pacientes con pcosUNESCO::CIENCIAS MÉDICASdisfunción endotelialcitoquinas proinflamatoriasresistencia a la insulinaenfermedad periodontal
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Impakteja sisältävän yhdistetyn aerobic- ja step-aerobic -harjoittelun mahdollisten vaikutusten pysyvyys lievää polvinivelrikkoa sairastavilla 50-65 …

2013

TIIVISTELMÄ IMPAKTEJA SISÄLTÄVÄN YHDISTETYN AEROBIC- JA STEP-AEROBIC -HARJOITTELUN MAHDOLLISTEN VAIKUTUSTEN PYSYVYYS LIEVÄÄ POLVINIVELRIKKOA SAIRASTAVILLA 50-65 -VUOTIAILLA NAISILLA - 12 kuukauden satunnaistetun ja kontrolloidun harjoitusintervention seurantatutkimus Maria Kasanen Fysioterapian Pro gradu -tutkielma Jyväskylän yliopisto, liikuntatieteiden tiedekunta, terveystieteiden laitos Kevät 2013 65 sivua, 10 liitettä Ohjaaja: Prof. Ari Heinonen ja tutkija Juhani Multanen, Jyväskylän yliopisto, Terveystieteiden laitos Terapeuttista harjoittelua suositellaan sen kipua vähentävien ja toimintakykyä parantavien vaikutusten vuoksi polvinivelrikon hoidoksi osittain ristiriitaisista tutkimustu…

aerobicnivelrikkonaisetstep-aerobicpolvetfyysinen toimintakykykipusatunnaistettu kontrolloitu tutkimusharjoitteluterapeuttinen harjoittelupolvinivelrikko
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Fast blue B functionalized silica-polymer composite to evaluate 3,5-dihy-droxyhydrocinnamic acid as biomarker of gluten intake

2021

Celiac disease is an immune-mediated systemic disorder elicited by gluten and related prolamines in genetically susceptible individuals. The current treatment is a strict and lifelong gluten-free diet. However, compliance with the gluten-free diet is not always adequate and many food products contain low concentrations of gluten. The determination of dietary transgressions is a challenge for patients, physicians and dietitians. Alkylresorcinols (AR) have been proposed as sensitive and specific biomarkers of gluten consumption. In this work silica-polymer composites doped with fast blue B reagent (FB) have been used to estimate alkylresorcinols in biological samples. The proposed colorimetri…

alkylresorcinols02 engineering and technology010402 general chemistry01 natural sciencesfast blue BMaterials ChemistryElectrical and Electronic EngineeringInstrumentationFast blueVolume concentrationchemistry.chemical_classificationChromatographyMetals and AlloysbiomarkersGluten intake021001 nanoscience & nanotechnologyCondensed Matter PhysicsGlutencapillary liquid chromatography0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryReagentFood productsPDMS compositesPolymer compositesBiomarker (medicine)0210 nano-technologyceliac disease
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La stérilité male cytoplasmique du tournesol (Helianthus annuus L.) : caractérisation des ADN chloroplastiques

1984

Notice présente dans BelInra (https://belinra.inra.fr/gestion/catalog.php?categ=isbd&id=83503); il s'agit d'un type de produit dont les métadonnées ne correspondent pas aux métadonnées attendues dans les autres types de produit : DISSERTATION; La stérilité male cytoplasmique du tournesol (Helianthus annuus L.) : caractérisation des ADN chloroplastiques

amélioration génétiquechloroplaste adncytoplasmic male sterilitysunflowerstérilité mâle cytoplasmiquepurificationrefininghelianthus annuusmarqueur génétiquesolvent free microwave extraction (sfem)physical map[SDV.BDLR]Life Sciences [q-bio]/Reproductive Biologysunflowersplante industrielleoléoprotéagineuxrestriction enzymestournesol[ SDV.BDLR ] Life Sciences [q-bio]/Reproductive Biologycarte de restrictionextractionprotein-oil cropenzyme de restriction[SDV.BDLR] Life Sciences [q-bio]/Reproductive Biology
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Molecular mechanisms of primary and secondary mucosal immunity using avian infectious bronchitis virus as a model system

2007

Although mucosal immune responses are critical for protection of hosts from clinical illness and even mortality caused by mucosal pathogens, the molecular mechanism of mucosal immunity, which is independent of systemic immunity, remains elusive. To explore the mechanistic basis of mucosal protective immunity, gene transcriptional profiling in mucosal tissues was evaluated after the primary and secondary immunization of animals with an attenuated avian infectious bronchitis virus (IBV), a prototype of Coronavirus and a well-characterized mucosal pathogen. Results showed that a number of innate immune factors including toll-like receptors (TLRs), retinoic-acid-inducible gene-1 (RIG-1), type I…

animal diseasesRespiratory Tract DiseasesLymphocyte Activationmedicine.disease_causeDC dendritic cellMucosal immunityCXCR chemokine (C-X-C motif) receptorCCR chemokine (C-C motif) receptorOligonucleotide Array Sequence AnalysisCoronavirusbiologyReverse Transcriptase Polymerase Chain ReactionAcquired immune systemSpecific Pathogen-Free OrganismsCytokinesAntibodyAvian infectious bronchitis virusCoronavirus InfectionsIBV infectious bronchitis virusInfectious bronchitis virusImmunologychemical and pharmacologic phenomenaArticlePrimary and secondary immunityMolecular mechanismIBVTranscriptional regulationImmune systemImmunitymedicineAnimalsIFN interferonTLR toll-like receptorImmunity MucosalPoultry DiseasesInnate immune systemGeneral VeterinaryGene Expression ProfilingComplement System ProteinsTh1 Cellsbiochemical phenomena metabolism and nutritionCTL cytotoxic T lymphocytebiology.organism_classificationIg immunoglobulinIL interleukinMucosal immunologyImmunologybiology.proteinRNAbacteriaImmunizationChickensVeterinary Immunology and Immunopathology
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Focus on the Small GTPase Rab1: A Key Player in the Pathogenesis of Parkinson’s Disease

2021

Parkinson’s disease (PD) is the second most frequent neurodegenerative disease. It is characterized by the loss of dopaminergic neurons in the substantia nigra and the formation of large aggregates in the survival neurons called Lewy bodies, which mainly contain α-synuclein (α-syn). The cause of cell death is not known but could be due to mitochondrial dysfunction, protein homeostasis failure, and alterations in the secretory/endolysosomal/autophagic pathways. Survival nigral neurons overexpress the small GTPase Rab1. This protein is considered a housekeeping Rab that is necessary to support the secretory pathway, the maintenance of the Golgi complex structure, and the regulation of macroau…

autophagyParkinson's diseaseQH301-705.5Substantia nigraReviewBiologyCatalysisInorganic Chemistryα-synucleinmedicineAnimalsHumansSmall GTPaseBiology (General)Physical and Theoretical ChemistryQD1-999Molecular BiologySpectroscopySecretory pathwayRab1GTPasesOrganic ChemistryNeurodegenerationDopaminergicRAB1Parkinson DiseaseLRRK2General Medicinemedicine.diseaseLRRK2Computer Science Applicationssecretory pathwayrab1 GTP-Binding ProteinsChemistrynervous systemParkinson’s diseaseNeuroscienceGolgi fragmentationInternational Journal of Molecular Sciences
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Distinct bhaplotype structure at the innate immune receptor Toll-like receptor 2 across bank vole populations and lineages in Europe

2015

Abstract: Parasite-mediated selection may contribute to the maintenance of genetic variation at host immune genes over long time scales. To date, the best evidence for the long-term maintenance of immunogenetic variation in natural populations comes from studies on the major histocompatibility complex (MHC) genes, whereas evidence for such processes from other immune genes remains scarce. In the present study, we show that, despite pronounced population differentiation and the occurrence of numerous private alleles within populations, the innate immune gene Toll-like receptor 2 (TLR2) displays a distinct haplotype structure in 21 bank vole (Myodes glareolus) populations across Europe. Haplo…

balancing selectionPopulationphylogeographyBalancing selectionMajor histocompatibility complexToxicologydiversitypolymorphismsmall mammalspositive darwinian selectionMyodes glareolusGenetic variationmaintenance of genetic variationTLR2mhceducationclethrionomys-glareolusBiologyEcology Evolution Behavior and SystematicsToxicologieVLAGGeneticseducation.field_of_studyToll-like receptorInnate immune systembiologyHaplotypebiology.organism_classificationmajor histocompatibility complexparasite resistanceimmunogeneticsBank voleEvolutionary biologynorthern spaingene evolutionbiology.proteinta1181genetic-variationroderentscontrasting patterns
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Ceylon cinnamon and its major compound Cinnamaldehyde can limit overshooting inflammatory signaling and angiogenesis in vitro: implications for COVID…

2021

AbstractOvershooting immune reactions can occur during inflammatory responses that accompany severe infections, such as COVID-19. Cytokines, damage-associated molecular patterns (DAMPs), and reactive oxygen and nitrogen species can generate positive feedback loops of inflammation, leading to long-term complications such as vascular endothelialitis, thrombosis, endothelial dysfunction, neurological impairments, and chronic fatigue. Dexamethasone can limit inflammation by inhibiting the activation of pro-inflammatory transcription factors. High dose dexamethasone, however, has undesirable side effects. Here, we show that Ceylon cinnamon and its major compound cinnamaldehyde can mitigate infla…

biologyChemistryAngiogenesisfungifood and beveragesInflammationPharmacologyHMGB1medicine.diseaseCinnamaldehydechemistry.chemical_compoundmedicineTLR4biology.proteinmedicine.symptomEndothelial dysfunctionReceptorDexamethasonemedicine.drug
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Sella, A NEW NAME FOR THE GENUS Linaresia EL KADIRI, 1992 (NASSELLARIA, RADIOLARIA) PREOCCUPIED BY COPEPOD CRUSTACEANS (LAMIPPIDAE, MAXILLOPODA)

2021

The aim of this short note is to create a new name of this genus since the original name Linaresia proved to pre-exist in the paleontological literature ( Linaresia de Zulueta, 1908, Family Lamippidae, Copepod crustaceans, and Linaresia Gonzalez-Donoso, 1968, Family Gavelinellidae, Agglutinated Foraminifera). The new name created for the above mentioned radiolarians is: Sella . This name derives from an arbitrary combination of letters (International Code of Zoological Nomenclature). The type species of Sella is S. beniderkoulensis by original designation (El Kadiri, 1992).

biologyInternational Code of Zoological Nomenclatureroyalty.order_of_chivalryPaleontologyroyaltyZoologybiology.organism_classificationQE701-760NassellariaForaminiferaType speciesGenusMaxillopodaCopepodRadiolariaSpanish Journal of Palaeontology
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Evolution and Immune Function of Fish Lectins

2016

Abstract Lectins are sugar-binding proteins widely distributed among animals, plants, and microbial taxon, involved in diverse biological processes. In both invertebrates and vertebrates, they play key roles in nonself recognition and immune responses, such as nonself recognition, inflammatory processes, and immunomodulation. In fish, many lectin families have been identified, and their tissue-specific expression and localization of the various lectin repertoires and their ligands are consistent with their distinct biological roles in innate and adaptive immunity. Here, we discuss the involvement of F-type lectins, rhamnose-binding lectins, galectins, and C-type lectins in pathogen recognit…

biologyLectinchemical and pharmacologic phenomenaAcquired immune systemCell biologyKLRB1BiochemistryC-type lectinLectin pathwaybiology.proteinFicolinimmunity fish lectin inflammationMannan-binding lectinGalectin
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