Search results for "LR"

showing 10 items of 764 documents

Knee arthroplasty until age 60 : role of sports and other injuries

2019

BACKROUND: The primary aim of the study was to investigate how total knee arthroplasty (TKA) patients with underlying injuries differ in injury type and physical activity after the arthroplasty. METHODS: A questionnaire was sent to TKA patients, < 60 years at surgery, and knee injury as the cause of knee OA. The final study group consisted of 70 patients. RESULTS: Average age of patients at TKA was 51.8 years (Standard Deviation [SD] 5.2), and at follow-up 57.6 years (SD 6.5). Of the injuries, 26% were sports-related, 29% had occurred at work, 23% in traffic accidents, and 13% during leisure-time (no sports-related). Sports-related injuries had occurred at younger ages than others had (mean…

osteoarthritisnivelrikkoexercisepolvetkneearthroplastyliikuntareplacementhuman activitiesknee injurypolvivammat
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Predictive value of p53, Ki67 and TLR5 in neoplastic progression of Barrett’s esophagus: a matched case–control study

2022

Abstract Barrett’s esophagus progresses to high-grade dysplasia or cancer along the well-established metaplasia-dysplasia-adenocarcinoma sequence. The aim of this study was to evaluate the value of p53, Ki67, and toll-like receptor 5 (TLR5) in prediction of malignant progression of Barrett’s metaplasia and low-grade dysplasia. This was a retrospective matched case–control study based on Northern and Central Finland population. Patients diagnosed with esophageal high-grade dysplasia or adenocarcinoma were included. From these patients, all previous endoscopy samples were obtained along with original diagnostic HE-slides and clinical data. Age- and sex-matched patients with non-progressing Ba…

p53Esophageal NeoplasmsbiomarkkeritAdenocarcinomaPathology and Forensic MedicineimmunohistokemiaBarrett EsophagusHumansBarrett’s esophagusTLR5Molecular BiologyRetrospective StudiesMetaplasiaSurveillanceCell BiologyGeneral MedicineImmunohistochemistrydigestive system diseasesToll-Like Receptor 5antigeenitKi-67 AntigenDysplasia markerCase-Control StudiesproteiinitEsophageal adenocarcinomatarkkailuTumor Suppressor Protein p53ruokatorvisyöpäKi67Virchows Archiv
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Sekundārās traumas, stresa pārvarēšanas stratēģiju un aizstājošās posttraumatiskās izaugsmes saistības krīzes tālruņa konsultantiem

2021

Aizvien vairāk pētījumu tiek veltīti palīdzošajām profesijām, un pievērsta lielāka uzmanība tam, kādu iespaidu trauma var atstāt arī uz tiem cilvēkiem, kas sniedz atbalstu traumu upuriem. Bakalaura pētījuma darba mērķis ir noskaidrot, vai pastāv savstarpējas saistības starp trīs konstruktiem - sekundāro traumu, stresa pārvarēšanas stratēģijām un aizstājošo posttraumatisko izaugsmi - krīzes un atbalsta tāruņa konsultantu izlasē. Pētījumā piedalījās 58 krīzes konsultanti vecumā no 20 līdz 75 gadiem (M=39,81; SD=10,13), no kuriem 5 bija vīrieši (8,6%) un pārējās sievietes (n=53 vai 90,4%) ar dažādu nostrādāto stundu skaitu pie krīzes tālruņa (20-5280h). Datu ievākšanai tika izmantotas trīs lat…

palīdzošās profesijaskrīzes un atbalsta tālruņa konsultantistresa pārvarēšanas stratēģijasaizstājošā posttraumatiskā izaugsmePsiholoģijasekundārā trauma
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When earwig mothers do not care to share: Parent–offspring competition and the evolution of family life

2017

Kin competition often reduces – and sometimes entirely negates – the benefits of cooperation among family members. Surprisingly, the impact of kin competition on the fitness effects of family life only received close scrutiny in studies on sibling rivalry, whereas the possibility of parent–offspring competition has attracted much less attention. As a consequence, it remains unclear whether and how parent–offspring competition could have affected the early evolution of parental care and family life. Here, we examined the occurrence and consequences of parent–offspring competition over food access in the European earwig Forficula auricularia, an insect with facultative family life reminiscent…

parent-offspring competition0106 biological sciences0301 basic medicineSibling rivalry (animals)Offspringmedia_common.quotation_subjectparental careparent-offspring conflict.010603 evolutionary biology01 natural sciencesCompetition (biology)03 medical and health sciencesForficula auriculariaEuropean earwigkin competitionorphaningEcology Evolution Behavior and Systematicsmedia_commonbiologyEcologybiology.organism_classificationFamily lifeenvironmental conditions[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology030104 developmental biologyEarwigfamily lifeParent–offspring conflictPaternal careDemographyFunctional Ecology
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YAlO3 svārstību spektroskopija

2022

Pētījuma gaitā tiek apskatīts optoelektronikā daudz pielietojams perovskitveida kristāls – YAlO3 (YAP). Tam tiek modelēta kristāliskā režģa dinamika, izmantojot pirmo principu (ab initio) un klasiskās molekulārdinamikas aprēķinus programmā CRYSTAL un GULP. Iegūtas fononu dispersijas un stāvokļu blīvumu līknes, eksperimentāli ģenerēti Ramana un infrasarkanie spektri. Ar rentgenstaru difrakciju noteikti YAP kristāla režģa parametri, tie salīdzināti ar DFT un klasisko aprēķinu optimizēto struktūru. Ar Ramana un infrasarkanās atstarošanās spektroskopijas metodēm mērīti monokristāliski YAP kristāla paraugi. Iegūti polarizēti Ramana spektri pie istabas un pie zemām temperatūrām (10 K), atklātas i…

perovskitiinfrasarkanā spektroskopijadinamikaFizikakristālrežģiRamana spektroskopija
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Induction of body weight loss through RNAi-knockdown of APOBEC1 gene expression in transgenic rabbits

2014

In the search of new strategies to fight against obesity, we targeted a gene pathway involved in energy uptake. We have thus investigated the APOB mRNA editing protein (APOBEC1) gene pathway that is involved in fat absorption in the intestine. The APOB gene encodes two proteins, APOB100 and APOB48, via the editing of a single nucleotide in the APOB mRNA by the APOBEC1 enzyme. The APOB48 protein is mandatory for the synthesis of chylomicrons by intestinal cells to transport dietary lipids and cholesterol. We produced transgenic rabbits expressing permanently and ubiquitously a small hairpin RNA targeting the rabbit APOBEC1 mRNA. These rabbits exhibited a moderately but significantly reduced …

perte de poidsobesityApolipoprotein BAgricultural BiotechnologyGene Expressionlcsh:MedicinetransgenesisSmall hairpin RNAAnimals Genetically Modified0302 clinical medicinesirnaRNA interferenceGene expressionGene Knockdown TechniquesBiologie de la reproductionMedicine and Health SciencesTransgenesIntestinal MucosaRNA Small Interferinglcsh:Science[SDV.BDD]Life Sciences [q-bio]/Development Biology2. Zero hunger0303 health sciencesGene knockdownReproductive BiologyMultidisciplinarybiologyGenetically Modified OrganismsBiologie du développementapobec1; obesity; editing apob; apob100; apob48; chylomicron; intestine; rabbit; sirna; transgenesis; knockdownchylomicronknockdownAgricultureInherited Metabolic DisordersDevelopment BiologyobésitéCholesterolPhenotypeTransgenic Engineering[ SDV.BDLR ] Life Sciences [q-bio]/Reproductive BiologyLiverapobapob48Gene Knockdown Techniquesanimal transgéniqueRNA Interferencelipids (amino acids peptides and proteins)RabbitsGenetic EngineeringResearch ArticleBiotechnologyexpression géniqueTransgeneAPOBEC-1 DeaminaseMolecular Sequence DatarabbitDiet High-Fat03 medical and health sciencesintestinCytidine DeaminaseWeight Loss[SDV.BDD] Life Sciences [q-bio]/Development BiologyAnimalsHumanslapinRNA Messenger[ SDV.BDD ] Life Sciences [q-bio]/Development BiologyintestineTriglycerides[SDV.BDLR] Life Sciences [q-bio]/Reproductive Biology030304 developmental biologyapobec1Base SequenceGenetically Modified AnimalsAPOBEC1editinglcsh:RBiology and Life Sciences[SDV.BDLR]Life Sciences [q-bio]/Reproductive BiologyMolecular biologyapob100DyslipidemiaMetabolic Disordersbiology.proteinlcsh:QRNA EditingApolipoprotein B-48030217 neurology & neurosurgery
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The martial art of judo as educational contents for children who living in an open society

2014

pluralizmsztuki walkipedagogymartial artspedagogikawychowanie dziecipluralismrivalrychildren upbringingjudowychowanie agonistyczneIdo Movement for Culture. Journal of Martial Arts Anthropology
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Mobiilisovelluksen käytettävyys kotiharjoittelun ohjauksessa lievää polven nivelrikkoa sairastavilla postmenopausaalisilla naisilla

2015

TIIVISTELMÄ Kirsi Ahde (2015). Mobiilisovelluksen käytettävyys kotiharjoittelun ohjauksessa lievää polven nivelrikkoa sairastavilla postmenopausaalisilla naisilla. Terveystieteiden laitos. Jyväskylän yliopisto, (fysioterapia) pro gradu tutkielma, 59 s., 7 liitettä. Tämän satunnaistetun ja kontrolloidun intervention tarkoituksena oli tutkia mobiilisovelluksen käytettävyyttä lievää polven nivelrikkoa sairastavien naisten kotiharjoittelun ohjauksessa. Lisäksi tutkittiin intervention aikaista dynaamisen tasapainon sekä alaraajojen maksimaalisen voimantuottotehon muutosta. Tutkimus oli osa Jyväskylän yliopiston Arjen mobiilisovellusten hanketta. Tutkimukseen osallistui 23 vapaaehtoista 54-66-vuo…

polven nivelrikkonaisetnivelrikkomobiilisovelluskäytettävyyspolvetkotiharjoittelumobiilisovelluksetharjoitteluetäkuntoutuskuntoutusteleterveydenhuolto
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Alussa oli pelko ja kauhu kauhun viehätyksestä, kauhuelokuvista ja hirviöistä

2008

portrait of serial killer (elokuva) [Henry]demonitpaholainenkauhukirjallisuuskauhuelokuvatpelkoHellraiser(elokuva)kauhugoottikulttuurihirviöt
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Fra le reti e la città. Lo spazio delle nuove stazioni per l'Alta Velocità

2014

Between networks and cities: Architectural space in the new High-Speed train stations. Over the past thirty years, megainvestment rail projects in Western Europe have become powerful transformation vectors. An extensive literature addresses the issue with an urban engineering oriented approach, concerned primarily with the large scale and focusing on governance and urban planning. This monograph section of “Trasporti & Cultura” examines the relationship of new high-speed railroad stations to their cities. The objective is to investigate the depth and meaning of the transformations being wrought by the new stations, in a comparative international scenario. Articles on Japan and China are fol…

railroad high speed station infrastructural architecture urban regenerationSettore ICAR/14 - Composizione Architettonica E Urbana
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