Search results for "LSA"

showing 10 items of 832 documents

Aortic valve-sparing root replacement from inside the aorta using three Dacron skirts preserving the native Valsalva sinuses geometry and stabilizing…

2009

We present an alternative idea for valve-sparing technique combining the advantages of the reimplantation and the benefits of the remodeling techniques. We replace the sinuses of Valsalva using three Dacron skirts from inside of the aorta. The physiological anatomy of the Valsalva sinuses and their dynamic properties are preserved and the aortic commissures displacement avoided. The distal rim of each Dacron skirt was anchored to the aorto-ventricular junction using Ticron (2-0) U stitches placed from the ventricular side to the aortic side. We stabilize the base of the aortic annulus to prevent future dilation.

Pulmonary and Respiratory MedicineAortic valveAortic root aneurysm; Valve-sparing surgery; Easy procedurePolyestersAortic root aneurysmAortic DiseasesProsthesis DesignBlood Vessel Prosthesis ImplantationEasy proceduremedicine.arteryMedicineHumanscardiovascular diseasesCardiac skeletonSurgical ReplantationAortaCardiopulmonary BypassSuturesbusiness.industryPolyethylene TerephthalatesSettore MED/23 - Chirurgia CardiacaAnatomySinus of ValsalvaAortic AneurysmBlood Vessel ProsthesisValve-sparing surgeryParanasal sinusesmedicine.anatomical_structureTreatment OutcomeAortic Valvecardiovascular systemSurgeryCardiology and Cardiovascular MedicinebusinessTomography X-Ray Computedcirculatory and respiratory physiologyDilatation PathologicInteractive cardiovascular and thoracic surgery
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A fast PC-interface for synchronized sampling of digital data

1994

We describe a high-speed interface unit for a PC-like microcomputer used for pulsar observations at the Northern Cross radiotelescope. The unit allows sampling synchronized to a master UTC clock and asynchronous output to a storage device with a peak data rate of about 2.5 MB/sec.

PulsarSpace and Planetary ScienceAsynchronous communicationbusiness.industryComputer scienceMicrocomputerInterface (computing)Digital dataSampling (statistics)Astronomy and AstrophysicsData ratebusinessComputer hardwareExperimental Astronomy
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Measuring Heart Rate with a Heat Flux Sensor

2021

Different wearable biosignal measurement applications require minimally obtrusive and highly sensitive sensors and methods of transducing the heart pulse into an electric signal. At the same time, the sensors should have minimal power consumption and preferably provide information about more than just the heart rate. In this study, a method employing a heat flux sensor for recording the pulsatile cardiac component of an arterial pulse waveform is presented. The output signals of a conventional photoplethysmography (PPG) sensor and a heat flux sensor were recorded and compared with one another. The results show that a heat flux sensor can be used for measurement of heart pulse, in addition t…

Pulse (signal processing)business.industryAcousticsPhotoplethysmogramHeat flux sensorHeart ratePulsatile flowWearable computerWaveformMedicineBiosignalbusiness2021 IEEE International Instrumentation and Measurement Technology Conference (I2MTC)
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Molecular chaperones and mirnas in epilepsy: Pathogenic implications and therapeutic prospects

2021

Epilepsy is a pathologic condition with high prevalence and devastating consequences for the patient and its entourage. Means for accurate diagnosis of type, patient monitoring for predicting seizures and follow up, and efficacious treatment are desperately needed. To improve this adverse outcome, miRNAs and the chaperone system (CS) are promising targets to understand pathogenic mechanisms and for developing theranostics applications. miRNAs implicated in conditions known or suspected to favor seizures such as neuroinflammation, to promote epileptic tolerance and neuronal survival, to regulate seizures, and others showing variations in expression levels related to seizures are promising ca…

QH301-705.5Adverse outcomesReviewDiseaseBioinformaticsCatalysisInorganic ChemistryEpilepsychaperone systemmicroRNAmedicineAnimalsHumansBiology (General)Physical and Theoretical ChemistryQD1-999Molecular BiologyHeat-Shock ProteinsSpectroscopyNeuroinflammationmiRNAHigh prevalencebiologybusiness.industryOrganic Chemistrymolecular chaperonesGeneral Medicinetemporal lobe epilepsymedicine.diseaseComputer Science ApplicationsMicroRNAsChemistryChaperone (protein)Molecular targetsbiology.proteinepilepsyAnticonvulsantsbusiness
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Multidimensional frailty and quality of life: data from the English Longitudinal Study of Ageing

2022

Abstract Purpose Frailty has been found to be associated with poor quality of life (QoL) in older people, but data available are limited to cross-sectional studies. We therefore aimed to assess the association between multidimensional frailty, determined by Multidimensional Prognostic Index (MPI), with mortality and good QoL expectancy (GQoLE) in a large representative sample of older adults, over 10 years of follow-up. Methods In the English Longitudinal Study of Ageing, using the data from 2004–2005 and 2014–2015, MPI was calculated using a weighted score of domains of comprehensive geriatric assessment, i.e., number of difficulties in activities of daily living (ADL) and instrumental ADL…

Quality of lifeMaleAgingFrailtyPublic Health Environmental and Occupational HealthELSAELSA Frailty Mortality Multidimensional prognostic index Quality of lifeELSA; Frailty; Mortality; Multidimensional prognostic index; Quality of life; Activities of Daily Living; Aged; Aging; Cross-Sectional Studies; Female; Geriatric Assessment; Humans; Longitudinal Studies; Male; Quality of Life; FrailtyCross-Sectional StudiesMultidimensional prognostic indexActivities of Daily LivingHumansFemaleLongitudinal StudiesMortalityGeriatric AssessmentAged
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Sarcopenia reduces quality of life in the long-term: Longitudinal analyses from the English Longitudinal Study of Ageing

2022

Abstract Purpose Mixed findings exist for sarcopenia/quality of life (QoL) relationship. Moreover, the majority of studies in this area have utilized a cross-sectional design or specific clinical populations. Therefore, the aim of the present study was to examine the association between sarcopenia at baseline and QoL at 10 years follow-up in a large representative sample of older English adults. Methods Sarcopenia was diagnosed as having low handgrip strength and low skeletal muscle mass index. QoL was measured using the CASP (control, autonomy, self-realisation and pleasure)-19, with higher values reflecting higher QoL. Multivariable logistic regression analysis was conducted to assess pro…

Quality of lifeMaleAgingSarcopeniaHand StrengthEpidemiologyELSAAgeingCross-Sectional StudiesAgeing; ELSA; Epidemiology; Longitudinal; Older adults; Quality of life; Sarcopenia; Aged; Aging; Cross-Sectional Studies; Female; Hand Strength; Humans; Longitudinal Studies; Male; Quality of Life; SarcopeniaOlder adultsLongitudinalQuality of LifeHumansFemaleQuality of life Sarcopenia ELSA Older adults Epidemiology Longitudinal AgeingLongitudinal Studieshuman activitiesAged
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The contribution of the Italian Northern Cross Radiotelescope to the Gamma-Ray Observatory Pulsar Timing Network

1992

The observation of pulsars at gamma-ray energy requires updated pulsar parameters in order to fold the gamma-ray data over time intervals of weeks. The Compton Gamma-Ray Observatory Institute has set up an international agreement including several radiotelescopes and pulsar observers in order to provide a suitable timing support at radio wavelengths. In this paper we describe the system used at the Italian Northern Cross for the pulse timing observations related to the GRO mission.

Radio telescopePhysicsPulsarObservatoryMillisecond pulsarAstrophysics::High Energy Astrophysical PhenomenaAstrophysics::Instrumentation and Methods for AstrophysicsGamma rayAstronomyCosmic rayGamma-ray astronomyAstrophysicsBinary pulsarIl Nuovo Cimento C
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Search for radio pulsations in four anomalous X-ray pulsars and discovery of two new pulsars

2007

We have performed deep searches for radio pulsations from four southern anomalous X-ray pulsars (AXPs) to investigate their physical nature in comparison with the rotation powered pulsars. The data were acquired using the Parkes radio telescope with the 1.4 GHz multibeam receiver. No pulsed emission with periodicity matching the X-ray ephemeris have been found in the observed targets down to a limit of ∼0.1 mJy. A blind search has also been performed on all the 13 beams of the multibeam receiver (the central beam being pointed on the target AXP), leading to the serendipitous discovery of two new radio pulsars and to the further detection of 18 pulsars. Also a search for single dispersed pul…

Radio telescopePhysicsPulsarSpace and Planetary ScienceAstrophysics::High Energy Astrophysical PhenomenaAstrophysics::Instrumentation and Methods for AstrophysicsAstronomyAstronomy and AstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsEphemerisAstrophysics::Galaxy AstrophysicsCosmology
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Search for radio pulsations in four Anomalous X-ray Pulsars and discovery of two new pulsars

2006

We report on observations of four southern Anomalous X-ray Pulsars, (1RXS J170849.0-400910, 1E 1048.1-5937, 1E 1841-045 and AX J1845-0258), obtained at 1.4 GHz using the Parkes radio telescope. Radio pulsations from these sources have been searched (i) by directly folding the time series at a number of trial periods centered on the value of the spin rate obtained from the X-ray observations; (ii) by performing a blind search; (iii) using a code sensitive to single dedispersed pulses, in the aim to detect signals similar to those of the recently discovered Rotating RAdio Transients. No evidence for radio pulsations with an upper limit of ~0.1 mJy for any of the four targets has been found. T…

Radio telescopePhysicsPulsarSpace and Planetary ScienceAstrophysics::High Energy Astrophysical PhenomenaSpin rateAstrophysics (astro-ph)FOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsSpin-½
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Cost-effectiveness of zofenopril in patients with left ventricular systolic dysfunction after acute myocardial infarction: a post hoc analysis of SMI…

2013

Claudio Borghi,1 Ettore Ambrosioni,1 Stefano Omboni,2 Arrigo FG Cicero,1 Stefano Bacchelli,1 Daniela Degli Esposti,1 Salvatore Novo,3 Dragos Vinereanu,4 Giuseppe Ambrosio,5 Giorgio Reggiardo,6 Dario Zava7 1Unit of Internal Medicine, Policlinico S Orsola, University of Bologna, Bologna, Italy; 2Italian Institute of Telemedicine, Varese, Italy; 3Division of Cardiology, University of Palermo, Palermo, Italy; 4University and Emergency Hospital, Bucharest, Romania; 5Division of Cardiology, University of Perugia, Perugia, Italy; 6Mediservice, Milano, Italy; 7Istituto Lusofarmaco d'Italia SpA, Peschiera Borromeo, Italy Background: In SMILE-4 (the Survival of Myocardial Infarction Long-term…

Ramiprilmedicine.medical_specialtyCost effectivenessEconomics Econometrics and Finance (miscellaneous)Populationacute myocardial infarctionramiprilchemistry.chemical_compoundInternal medicinePost-hoc analysismedicinezofenoprilMyocardial infarctioneducationcost-effectivenesshealth care economics and organizationsOriginal Researchleft ventricular dysfunctioneducation.field_of_studylcsh:R5-920business.industryHealth Policylcsh:RM1-950acetylsalicylic acidmedicine.diseaseSMILE studycost effectiveness analysis (CEA)Confidence intervalZofenoprilangiotensin-converting enzyme inhibitorsClinicoEconomics and Outcomes Researchlcsh:Therapeutics. PharmacologychemistryCardiologyNumber needed to treatMedical emergencybusinesslcsh:Medicine (General)medicine.drug
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