Search results for "LSU"

showing 10 items of 384 documents

CCDC 637565: Experimental Crystal Structure Determination

2007

Related Article: Xiao-Yu Cao, J.Harrowfield, J.Nitschke, J.Ramirez, A.-M.Stadler, N.Kyritsakas-Gruber, A.Madalan, K.Rissanen, L.Russo, G.Vaughan, J.-M.Lehn|2007|Eur.J.Inorg.Chem.||2944|doi:10.1002/ejic.200700235

Space GroupCrystallographyhexakis(Dimethylsulfoxide)-copper(ii) bis(trifluoromethanesulfonate)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1568972: Experimental Crystal Structure Determination

2017

Related Article: Carlos Rojas-Dotti, José Martínez-Lillo|2017|RSC Advances|7|48841|doi:10.1039/C7RA09841C

Space GroupCrystallographyhexakis(mu-2-(N'-oxidocarbamimidoyl)phenolato)-bis(mu-oxo)-bis(3-(acetylsulfanyl)propanoato)-hexakis(ethanol)-hexa-manganese(iii) ethanol solvate dihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 708233: Experimental Crystal Structure Determination

2009

Related Article: C.Bonnot, J.-C.Chambron, E.Espinosa, K.Bernauer, U.Scholten, R.Graff|2008|J.Org.Chem.|73|7871|doi:10.1021/jo801438d

Space GroupCrystallographyrac-3^5^11^5^15^5^23^5^26^5^34^5^-Hexa-t-butyl-5917212832-hexakis(p-tolylsulfonyl)-3^2^11^2^:15^2^23^2^:26^2^34^2^-tris(14-dithiabutano)-1-azonia-591317212832-hepta-aza-31115232634(13)-hexabenzenabicyclo(11.11.11)pentatriacontaphane chloride perdeuteroacetone solvate dihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1908615: Experimental Crystal Structure Determination

2019

Related Article: Santos Fustero, Miriam Rodenes, Raquel Román, Daniel M. Sedgwick, José Enrique Aguado, Vadim A. Soloshonok, Jianlin Han, Haibo Mei, Mercedes Medio‐Simon, Pablo Barrio|2019|Adv.Synth.Catal.|361|3860|doi:10.1002/adsc.201900464

Space GroupCrystallographyt-butyl 2-{1-[(t-butylsulfinyl)amino]-222-trifluoroethyl}-5-oxo-25-dihydro-1H-pyrrole-1-carboxylateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 254470: Experimental Crystal Structure Determination

2005

Related Article: R.Cejudo-Marin, G.Alzuet, S.Ferrer, J.Borras, A.Castineiras, E.Monzani, L.Casella|2004|Inorg.Chem.|43|6805|doi:10.1021/ic049718w

Space GroupCrystallographytetrakis(mu2-N-(13-Thiazol-2-yl)-N-(p-tolylsulfonyl)imino)-di-copper(ii)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

In Silico Design, Synthesis and Biological Evaluation of Anticancer Arylsulfonamide Endowed with Anti-Telomerase Activity

2022

Telomerase, a reverse transcriptase enzyme involved in DNA synthesis, has a tangible role in tumor progression. Several studies have evidenced telomerase as a promising target for developing cancer therapeutics. The main reason is due to the overexpression of telomerase in cancer cells (85–90%) compared with normal cells where it is almost unexpressed. In this paper, we used a structure-based approach to design potential inhibitors of the telomerase active site. The MYSHAPE (Molecular dYnamics SHared PharmacophorE) approach and docking were used to screen an in-house library of 126 arylsulfonamide derivatives. Promising compounds were synthesized using classical and green methods. Com…

SulfonamidesRPharmaceutical ScienceAnticancer compounds; Arylsulfonamide; Docking; Molecular dynamics; Pharmacophore modeling; Structure-based drug design; Sulfonamides; Telomerase inhibitorsMolecular dynamicsSettore CHIM/08 - Chimica FarmaceuticaArticleDockingRS1-441Anticancer compoundsTelomerase inhibitorsPharmacy and materia medicaDrug DiscoveryArylsulfonamideMedicineMolecular Medicinesulfonamides; arylsulfonamide; anticancer compounds; telomerase inhibitors; structure-based drug design; pharmacophore modeling; docking; molecular dynamicsStructure-based drug designPharmacophore modeling
researchProduct

Dependency of the in vitro stabilization of differentiated functions in liver parenchymal cells on the type of cell line used for co-culture.

1992

The differentiation status in cultures of primary rat liver parenchymal cells was determined by measuring the activities of various xenobiotic metabolizing enzymes. Most enzyme activities dropped rather rapidly in monocultures of parenchymal cells. The protein content and the activities of cytosolic epoxide hydrolase, glutathione S-transferase, and alpha-naphthol UDP-glucuronosyl transferase were, however, well stabilized in 7-day-old co-cultures of parenchymal cells with two different lines of rat liver nonparenchymal epithelial cells (NEC1 and NEC2). Phenol sulfotransferase and microsomal epoxide hydrolase activity were reduced in this coculture system after 7 days to about 30 and 20% of …

SulfotransferaseClinical BiochemistryBiologyCell LineXenobioticschemistry.chemical_compoundmedicineAnimalsGlutathione transferase activityGlucuronosyltransferaseEpoxide hydrolaseCells CulturedGlutathione TransferaseEpoxide HydrolasesProteinsCell DifferentiationCell BiologyGeneral MedicineGlutathioneArylsulfotransferaseRatsmedicine.anatomical_structurechemistryBiochemistryLiverCell cultureMicrosomal epoxide hydrolaseHepatocyteStem cellDevelopmental BiologyIn vitro cellulardevelopmental biology : journal of the Tissue Culture Association
researchProduct

Effect of donor substituents on thermally activated delayed fluorescence of diphenylsulfone derivatives

2019

This research was funded by the European Social Fund according to the activity ‘Improvement of researchers’ qualification by implementing world-class R&D projects’ of Measure No. 09.3.3-LMT-K-712. DG acknowledges to the ERDF PostDoc project No. 1.1.1.2/VIAA/1/16/177;

TADFMaterials sciencePhotoluminescenceBiophysicsQuantum yield02 engineering and technologyDiphenylsulphone010402 general chemistryPhotochemistry01 natural sciencesBiochemistrychemistry.chemical_compoundBathochromic shift:NATURAL SCIENCES:Physics [Research Subject Categories]CarbazoleSolvatochromismGeneral Chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsAtomic and Molecular Physics and Optics0104 chemical sciencesOLEDchemistryExcited stateDensity functional theoryEmitter0210 nano-technologyPhenoxazineJournal of Luminescence
researchProduct

Diphenylsulfone-based hosts for electroluminescent devices: Effect of donor substituents

2020

DG acknowledges to the ERDF PostDoc project No. 1.1.1.2/VIAA/1/16/177. This work was supported by the project of scientific co-operation program between Latvia, Lithuania and Taiwan ?Polymeric Emitters with Controllable Thermally Activated Delayed Fluorescence for Solution-processable OLEDs? (grant No. S-LLT-19-4). Support of the Lithuanian Academy of Sciences is gratefully acknowledged; Institute of Solid State Physics, University of Latvia as the Center of Excellence has received funding from the European Union’s Horizon 2020 Framework Programme H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under grant agreement No. 739508, project CAMART²

TADFMaterials sciencePhotoluminescenceGeneral Chemical EngineeringCarbazoleQuantum yield02 engineering and technologyElectroluminescence010402 general chemistry01 natural scienceschemistry.chemical_compoundOLED:NATURAL SCIENCES:Physics [Research Subject Categories]TrifluoromethylCarbazoleProcess Chemistry and TechnologyHost021001 nanoscience & nanotechnologyDiphenylsulfone0104 chemical sciencesCrystallographyOLEDchemistryQuantum efficiency0210 nano-technologyGlass transitionDyes and Pigments
researchProduct

Muižu centru izmantošana agrārās reformas laikā: Talsu apriņķa piemērs,1920.-1937.gads

2019

Bakalaura darba mērķis ir izpētīt muižu sadalīšanas procesu Latvijas agrārās reformas laikā – kā tika sadalīta un saimnieciski izmantota muižu zeme, kā mainījās to juridiskais stāvoklis un kādas sekas radīja muižu sadalīšana, izmantojot Talsu apriņķa muižu sadalīšanu kā piemēru. Agrārā reforma (1920. – 1937. g.) pilnībā izmainīja Latvijas saimniecību, atsavinot muižniekiem viņu īpašumus un iedalot tos jaunsaimniekiem, ierīkojot valsts saimniecības, piešķirot tos skolām vai pagastvaldēm, atstājot bijušajam īpašniekam. Nav veikti pētījumi par muižu izmantošanu agrārās reformas laikā, tāpēc Talsu apriņķa piemērs sniedz priekšstatu par reformas īstenošanu. Bakalaura darbā secināts, ka reformas …

Talsu apriņķisJaunsaimniecībasVēstureMuižasAgrārā reforma
researchProduct