Search results for "LTE"
showing 10 items of 4531 documents
Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae
2013
Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox cofactor in a wide variety of biological processes. Recent studies in Saccharomyces cerevisiae have shown that in response to iron deficiency, an RNA-binding protein denoted Cth2 coordinates a global metabolic rearrangement that aims to optimize iron utilization. The Cth2 protein contains two Cx8Cx5Cx3H tandem zinc fingers (TZFs) that specifically bind to adenosine/uridine-rich elements within the 3' untranslated region of many mRNAs to promote their degradation. The Cth2 protein shuttles between the nucleus and the cytoplasm. Once inside the nucleus, Cth2 binds target mRNAs and stimulate…
Coupled conditional backward sampling particle filter
2020
The conditional particle filter (CPF) is a promising algorithm for general hidden Markov model smoothing. Empirical evidence suggests that the variant of CPF with backward sampling (CBPF) performs well even with long time series. Previous theoretical results have not been able to demonstrate the improvement brought by backward sampling, whereas we provide rates showing that CBPF can remain effective with a fixed number of particles independent of the time horizon. Our result is based on analysis of a new coupling of two CBPFs, the coupled conditional backward sampling particle filter (CCBPF). We show that CCBPF has good stability properties in the sense that with fixed number of particles, …
A computational method for studying the relation between alternative splicing and DNA methylation.
2015
Alternative splicing is an important mechanism in eukaryotes that expands the transcriptome and proteome significantly. It plays an important role in a number of biological processes. Understanding its regulation is hence an important challenge. Recently, increasing evidence has been collected that supports an involvement of intragenic DNA methylation in the regulation of alternative splicing. The exact mechanisms of regulation, however, are largely unknown, and speculated to be complex: different methylation profiles might exist, each of which could be associated with a different regulation mechanism. We present a computational technique that is able to determine such stable methylation pa…
Fluvial activity of the late-glacial to Holocene “Bergstraßenneckar” in the Upper Rhine Graben near Heidelberg, Germany – first results
2022
Abstract. The term “Bergstraßenneckar” (BSN) refers to an abandoned course of the river Neckar. It flowed in a northern direction east of the river Rhine in the eastern part of the northern Upper Rhine Graben in southwestern Germany. The former meandering course merged with the Rhine ca. 50 km further north of the site of the present-day confluence near Mannheim. The palaeo-channels are still traceable by their depressional topography, in satellite images and by the curved boundaries of adjacent settlements and land parcels. In the plan view, satellite and aerial images reveal a succession of meander bends, with older bends being cut off from younger channels. Based on stratigraphic investi…
Strontium and oxygen isotope analyses reveal Late Cretaceous shark teeth in iron age strata in the Southern Levant
2020
La experiencia del Mercado Alternativo Bursátil para Empresas en Expansión (MaB-EE) en España
2015
EXPERIENCIA DEL MERCADO ALTERNATIVO BURSÁTIL PARA EMPRESAS EN EXPANSIÓN (MaB-EE) EN ESPAÑA Mª Ángeles Soler Movilla Universitat de València El marco general de la Tesis lo constituye el segmento del mercado bursátil español especialmente diseñado para la negociación de acciones de empresas de reducida capitalización: el Mercado Alternativo Bursátil para Empresas en Expansión (MaB-EE), perteneciente a Bolsas y Mercados Españoles Sistemas de Negociación SA (BME). Este mercado nace en el año 2009 como un nuevo intento de ofrecer a las pequeñas y medianas empresas españolas la posibilidad de financiarse mediante recursos propios en un mercado bursátil organizado. La creación de este mercado se …
El fomento de la mediación y de otros medios alternativos de justicia (también) en relación con la sustracción internacional de menores en Europa
2021
El decidido fomento de la mediación y de otros instrumentos MASC en el ámbito del Derecho de familia internacional constituye una constante, en los últimos tiempos, en el panorama comparado internacional. También en relación con aquellas disputas que involucran a menores. La UE no es ajena a este proceso y contribuye decididamente a éste. Aunque persisten dudas sobre la virtualidad real de estos mecanismos en la práctica diaria internacional.
La multidimensionalidad de una pandemia. Sociedad y Derecho en la era del post-coronavirus
2020
La multidimensionalidad de lecturas que se han abierto derivadas de los efectos del Covid-19 (filosófica, sociológica y jurídica) ofrece una oportunidad para reflexionar sobre algunas dicotomías –además de la ya clásica salud/economía- tales como riesgo-miedo/alteridad, individualismo/comunidad, así como a revisar algunos de los relatos y narrativas que han intentado explicar lo que esta crisis ha supuesto y el escenario post-pandémico que podría configurarse. A partir del análisis de las dimensiones filosófica y sociológica, se pretende sentar las bases para identificar qué cuestiones nucleares inciden en la dimensión jurídica y, a partir de ahí, apuntar algunos parámetros acerca de cómo p…
El arbitraje como solución de conflictos en propiedad intelectual
2000
Italian assisted negotiation: an additional tool to settle matrimonial property regime cases
2021
The assisted negotiation procedure highlighted the need to distinguish the various forms of justice in view to obtaining decisions that can effectively satisfy the interests of the family. In fact the agreements who discipline the family conflicts attributes a central role to the will of the couple in the collaborative search for suitable solutions for the management of the crisis of the emotional bond.