Search results for "LTE"

showing 10 items of 4531 documents

Fumaric acid ester treatment in cutaneous lupus erythematosus (CLE): a prospective, open-label, phase II pilot study.

2016

Objective The aim of the study was to assess the efficacy and safety of fumaric acid esters (FAEs) in patients with cutaneous lupus erythematosus (CLE). Methods In this 24-week, prospective, open-label, phase II pilot study, 11 patients with CLE, refractory to topical corticosteroids, were included. The primary endpoint of the study was the evaluation of the efficacy of FAEs after 24 weeks of treatment as assessed by the Revised Cutaneous Lupus Disease Area and Severity Index (RCLASI). Results Compared to baseline, significant improvement in the mean total RCLASI activity score and the mean RCLASI activity score for skin lesions was observed in week 12 ( p = 0.002, p = 0.002, respectively) …

AdultMaleFumaric acidmedicine.medical_specialtyColicPilot ProjectsSeverity of Illness IndexDrug Administration Schedule030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRheumatologyFumaratesLupus Erythematosus CutaneousMedicineHumansIn patientProspective Studies030203 arthritis & rheumatologybusiness.industryHeadacheMiddle AgedDermatologyAlternative treatmentClinical trialTreatment OutcomeFumaric Acid EsterschemistryCutaneous Lupus ErythematosusFemaleOpen labelbusinessLupus
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Rapid Self-Hypnosis: A New Self-Hypnosis Method and Its Comparison with the Hypnotic Induction Profile (HIP)

2001

Despite its clinical importance, there are few systematic studies on the application of self-hypnosis. Rapid Self-Hypnosis (RSH) was created to provide a new procedure that is easy, comfortable, fosters alertness, and can be done covertly in everyday life. We present it as an alternative to the self-hypnosis version of the Hypnosis Induction Profile (HIP). Using a crossover design, we found in an experimental session that the RSH and the HIP produced comparable objective and subjective scores in the Barber Suggestibility Scale (BSS). However, as compared with the HIP, participants rated RSH as significantly more coherent, pleasant, faster and easier to learn, more likely to be used in every…

AdultMaleHypnosisCross-Over StudiesPsychotherapistmedicine.drug_classAutogenic trainingSuggestibilityGeneral MedicineAdditional researchHypnoticAlertnessTreatment OutcomeComplementary and alternative medicineSelf-hypnosismedicineHumansFemaleAutogenic TrainingSuggestionPsychologyEveryday lifeHypnosisAmerican Journal of Clinical Hypnosis
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Preference between two methods of active-alert hypnosis: not all techniques are created equal.

1999

Abstract In a cross-over design (N = 80), we compared the differential liking and preference for two hypnotic techniques involving physical activity: Active-alert and waking-alert (or alert-hand) procedures. Participants expressed significantly higher liking and preference for the waking-alert as compared to the active-alert procedure. The latter technique, which also had significantly lower suggestibility scores (Cardena et al., 1998) was also associated with a significantly higher attrition rate (23%). These significant differences may be explained by the greater physical effort and difficulty associated with the active-alert technique. It seems that the waking-alert method extends the ad…

AdultMaleHypnosisCross-Over StudiesSuggestibilityPhysical activityPilot ProjectsGeneral Medicinemedicine.diseaseChoice BehaviorPreferenceDevelopmental psychologyAlertnessComplementary and alternative medicineSurveys and QuestionnairesmedicineHumansAttritionFemaleWakefulnessPsychologyHypnosisThe American journal of clinical hypnosis
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Attitudes Toward Hypnosis Based on Source of Information and Experience With Hypnosis.

2020

Attitudes and beliefs toward hypnosis are relevant in promoting hypnotic responses, in predicting the efficacy of interventions that include hypnosis, and in reducing iatrogenic effects in hypnotized individuals. The goal of the present study is to test the impact of previous knowledge about hypnosis and past experiences being hypnotized on attitudes and beliefs about hypnosis. A sample of 1,977 Portuguese students participated in the study; they responded to the Valencia Scale of Attitudes and Beliefs Toward Hypnosis-Client Version (VSABH-C) on two different occasions (test-retest method). Significant differences were found (

AdultMaleHypnosisHealth Knowledge Attitudes PracticePsychotherapistScale (ratio)PortugalUniversities05 social sciencesPsychological intervention050109 social psychologyGeneral MedicineIatrogenic effects03 medical and health sciencesYoung Adult0302 clinical medicineComplementary and alternative medicineHumans0501 psychology and cognitive sciencesFemalePsychologyStudents030217 neurology & neurosurgeryHypnosisThe American journal of clinical hypnosis
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Accommodative stimulus-response curves to low-pass filtered natural images

2018

To assess how the monocular steady-state accommodative stimulus-response curve is modified when viewing low-pass filtered natural images. Eighteen adult subjects participated in the study. The accommodative stimulus-response curve was objectively assessed by means of a Hartmann-Shack wavefront sensor. Measurements were taken at different accommodative demands. Target images were low-pass filtered versions of a natural image that were obtained applying different digital spatial filters that limited the spatial frequency content of the natural image. Cutoff spatial frequencies were set at 30, 21, and 15 cycles per degree (cy/deg). Mean data obtained for each target were fitted to linear model…

AdultMaleLow-pass filterRefraction Ocular050105 experimental psychologyYoung Adult03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineOpticsVision MonocularLinear regressionMyopiaHumansCutoff0501 psychology and cognitive sciencesMathematicsAnalysis of covarianceMonocularbusiness.industry05 social sciencesLinear modelAccommodation OcularWavefront sensorSensory SystemsOphthalmologySpace Perception030221 ophthalmology & optometryFemaleSpatial frequencybusinessPhotic StimulationGraefe's Archive for Clinical and Experimental Ophthalmology
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Cloning of the human NCNF gene.

1998

We have cloned from a cDNA library of human testis tissue the human homologue to the mouse nuclear orphan receptor NCNF (neuronal cell nuclear factor). The open reading frame encodes a protein of 480 amino acids, the sequence of which (EMBL accession no. X99975) is 98.3% identical to the mouse homologue. Northern blot analysis of adult human tissues revealed a broad pattern of tissue expression. Similar to NCNF expression in mouse testis, two transcript forms of the single copy gene are expressed in human tissues. The two transcript forms which differ only in their 3'UTR, result in human from differential polyadenylation, in mouse from alternative splicing. Based on the high level of sequen…

AdultMaleMolecular Sequence DataReceptors Cytoplasmic and NuclearBiologyBiochemistryMiceNuclear Receptor Subfamily 6 Group A Member 1Sequence Homology Nucleic AcidTestisAnimalsHumansNorthern blotAmino Acid SequenceCloning MolecularMolecular BiologyPeptide sequenceGeneCloningOrphan receptorRegulation of gene expressionBase SequencecDNA libraryAlternative splicingCell BiologyDNAMolecular biologyDNA-Binding ProteinsRepressor ProteinsAlternative SplicingGene Expression RegulationOrgan SpecificityJournal of receptor and signal transduction research
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Cigarette Smoking, But Not Sensitization toAlternaria, Is Associated with Severe Asthma in Urban Patients

2001

Hereditary susceptibility and allergen exposure have been identified as general risk factors for asthma. However, risk factors for severe asthma still remain to be identified. To further assess and quantify risk factors associated with severe asthma in adult patients apart from clinical exacerbations, 306 randomly selected subjects (mean age 40+/-17 years, 46% males) presenting to an inner city pulmonary practice between 1995 and 1996 were retrospectively investigated. Of these, 117 patients were atopic, 112 had current asthma, and 22 asthmatics had severe asthma. Risk factors associated with atopy were family history of atopy and any domestic pet ownership (OR: 3.1, 95% CI: 1.64-6.1). Asth…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyAllergyUrban Populationmedicine.disease_causeSeverity of Illness IndexAtopyAllergenRisk FactorsForced Expiratory VolumeGermanyInternal medicineImmunopathologyHypersensitivitymedicineHumansImmunology and AllergyFamily historyRisk factorRetrospective StudiesAsthmabusiness.industrySmokingRespiratory diseaseUrban HealthAlternariamedicine.diseaseAsthmarespiratory tract diseasesMultivariate AnalysisPediatrics Perinatology and Child HealthImmunologyFemalebusinessJournal of Asthma
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The Penile Plication Procedure: An Alternative Method for Straightening Penile Deviation

1991

AbstractThe number of reported cases of congenital and acquired penile deviation is evidently increasing. We describe our experience with the penile plication procedure, which we used to treat 40 patients with penile deviation. Postoperatively, all patients regained the ability for sexual intercourse, with potency remaining unimpaired. Of the patients 96% were completely satisfied with the result of the operation. Sustained complications have not been observed. To avoid major trauma the surgical intervention should not include removal of ellipsoids from the penile tunica albuginea as proposed by Nesbit. Since the penile plication method produces equally good results in terms of performance …

AdultMaleReoperationmedicine.medical_specialtyAdolescentUrologyPenile IndurationTunica albuginea (ovaries)Postoperative ComplicationsRecurrenceMethodsmedicineHumansAlternative methodsPlicaturabiologybusiness.industrySuture TechniquesPenile Indurationbiology.organism_classificationSurgerymedicine.anatomical_structurebusinessPlication procedurePenisFollow-Up StudiesPenisJournal of Urology
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Hypnosis Attitudes: Treatment Effects and Associations With Symptoms in Individuals With Cancer.

2017

Attitudes about hypnosis are associated with hypnotic responsiveness. However, little is known about how hypnosis attitudes change with treatment and if those changes are associated with better outcomes. This study examined whether an intervention based on the Valencia Model of Waking Hypnosis combined with Cognitive-Behavioral Therapy changed attitudes about hypnosis in a sample of patients with a history of cancer. The results indicated that the intervention improved attitudes toward hypnosis, relative to a control intervention, and the improvements remained stable at 3-month follow-up. Analyses also showed that changes in some attitudes were associated with treatment-related improvements…

AdultMaleSleep Wake Disorders050103 clinical psychologyHypnosisHealth Knowledge Attitudes PracticePsychotherapistmedicine.medical_treatmentTreatment outcomePain03 medical and health sciences0302 clinical medicineCancer SurvivorsIntervention (counseling)NeoplasmsOutcome Assessment Health CaremedicineHumans0501 psychology and cognitive sciencesDepression (differential diagnoses)FatigueAgedAged 80 and overCognitive Behavioral Therapy05 social sciencesCancerGeneral MedicineMiddle Agedmedicine.diseaseComplementary and alternative medicineCognitive therapyFemalesense organsPsychology030217 neurology & neurosurgeryHypnosisClinical psychologyThe American journal of clinical hypnosis
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Sleep phenotypes of intellectual disability: a polysomnographic evaluation in subjects with Down syndrome and Fragile X syndrome

2008

Abstract Objective To analyze sleep architecture and NREM sleep alterations by means of the Cyclic Alternating Pattern (CAP) in children with Down syndrome (DS) and Fragile-X syndrome (fraX), the two most common causes of inherited mental retardation, in order to find out eventual alterations of their sleep microstructure related to their mental retardation phenotypes. Methods Fourteen patients affected by fraX (mean age 13.1 years) and 9 affected by Down syndrome (mean age 13.8 years) and 26 age-matched normal controls were included. All subjects underwent overnight polysomnography in the sleep laboratory, after one adaptation night and their sleep architecture and CAP were visually scored…

AdultMaleSleep Wake Disordersmedicine.medical_specialtyFRAXAdolescentPolysomnographyDown syndromeRapid eye movement sleepPolysomnographyCyclic alternating patternAudiologyNon-rapid eye movement sleepStatistics NonparametricSettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'EducazionePhysiology (medical)Internal medicineFragile-X syndromemedicineHumansChildSlow-wave sleepNREM sleep microstructuremedicine.diagnostic_testSleep phenotypeElectroencephalographymedicine.diseaseSleep in non-human animalsSensory SystemsFragile X syndromeEndocrinologyPhenotypeNeurologyFragile X SyndromeFemaleNeurology (clinical)Sleep onsetPsychologySleep
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