Search results for "LTE"
showing 10 items of 4531 documents
Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial.
2011
Crataegus laevigata is a medicinal plant most commonly used for the treatment of heart failure and psychosomatic disorders. Based on previous experimental findings, this double-blind placebo-controlled study was aimed at finding beneficial effects of C. laevigata on biomarkers of coronary heart disease (CHD). The study included 49 diabetic subjects with chronic CHD who were randomly assigned to the treatment for 6 months with either a micronized flower and leaf preparation of C. laevigata (400 mg three times a day) or a matching placebo. Blood cell count, lipid profile, C-reactive protein, neutrophil elastase (NE) and malondialdehyde were analyzed in plasma at baseline, at one month and six…
Translational Research for Improving the Care of Familial Hypercholesterolemia: The “Ten Countries Study” and Beyond
2016
Familial hypercholesterolemia (FH) is the most common and serious form of inherited hyperlipidaemia. Dominantly inherited with high penetrance, untreated FH leads to premature death from coronary artery disease due to accelerated atherosclerosis from birth. Despite its importance, there is still a major shortfall in awareness, detection and treatment of FH worldwide. International models of care for FH have recently been published, but their effective implementation requires the garnering of more knowledge about the condition. The "Ten Countries Study" aims to investigate diagnostic, epidemiological and service aspects, as well as physician practices and patient experiences of FH in several…
Å være pårørende når alternativ behandling tas i bruk i “kampen mot kreft”
2015
<strong>Being relatives when alternative therapies are used in the "fight against cancer"</strong><br />CAM (Complementary and Alternative Medicine) is prevalent among cancer patients. Relatives are central to support and care for the patient but experience challenges and stresses in this role. The purpose of this study was to gain knowledge of how it is experienced to be relative of people with terminal cancer who seeks CAM. Five qualitative semi-structured in-depth interviews of relatives and nine biographies written by relatives were analyzed using systematic text condensation. Results showed that relatives experienced to fight for hope in a given battle, not knowing wh…
New strategies for medical management of overactive bladder in children.
2011
Purpose of review The medical treatment of children with non-neurogenic overactive bladder syndrome (OAB) is still limited to a small number of drugs approved for use in childhood according to the national regulations of each country. Recent findings Over the last few years, there were several studies on the use of antimuscarinics other than oxybutynin in children, as well as some on the use of extended release oxybutynin and tolterodine and transdermal oxybutynin. It was shown that the combination of two different anticholinergics might be a well tolerated and successful option in children with OAB refractory to monotherapy, as well as administration of a receptor-selective antimuscarinic …
Tissue bioaccumulation patterns, xenobiotic biotransformation and steroid hormone levels in Atlantic salmon (Salmo salar) fed a diet containing perfl…
2011
In the present study, groups of juvenile Atlantic salmon (Salmo salar) were fed gelatine capsules containing fish-food spiked with PFOA or PFOS (0.2 mg kg(-1) fish) and solvent (methanol). The capsules were given at days 0, 3 and 6. Blood, liver and whole kidney samples were collected prior to exposure (no solvent control), and at days 2, 5, 8 and 14 after exposure (Note: that day 14 after exposure is equal to 7d recovery period). We report on the differences in the tissue bioaccumulation patterns of PFOS and PFOA, in addition to tissue and compound differences in modulation pattern of biotransformation enzyme genes. We observed that the level of PFOS and PFOA increased in the blood, liver …
The role of long-acting injectable antipsychotics in schizophrenia: a critical appraisal
2014
Despite their widespread use, long-acting injectable (LAI) antipsychotics (APs) are often regarded with some negativity because of the assumption of punishment, control and insufficient evolution towards psychosocial development of patients. However, LAI APs have proved effective in schizophrenia and other severe psychotic disorders because they assure stable blood levels, leading to a reduction of the risk of relapse. Therapeutic opportunities have also arisen after introduction of newer, second-generation LAI APs in recent years. Newer LAI APs are more readily dosed optimally, may be better tolerated and are better suited to integrated rehabilitation programmes. This review outlines the …
Alternative methods of mechanical Cardiopulmonary Resuscitation
2000
Due to the relative ineffectiveness of standard resuscitation techniques, alternative methods have been explored for many years. The aim of new methods is to improve haemodynamics and increase survival rates. In spite of some encouraging haemodynamic results, all but one study failed to show an increase in long-term survival rates with an alternative method in a convincingly large group of patients (hospital discharge without neurological damage, and 1-year survival). In this study active compression-decompression resuscitation (ACD-CPR) increased long-term survival compared to standard-CPR. The results from certain individual studies, which showed a significant increase in short-term survi…
Geschlecht und Gender in der Medizin
2005
Gender specific medicine is a part of gender-research, which has been insufficiently considered up to the present in medicine, sanitation and politics. Part of the scientific medicine simply ignores the knowledge that menand women are different in feeling, thinking and social acting without any question. Doctors often incline to treat all their patients as if there was just one gender: i. e. the male one. It is without dispute that men and women vastly suffer from the same diseases, but they often go through them quite differently. The female body seems to work differently from the male one in nearly all respects - starting with the brain, going on with the heart, cardiovascular, lungs, sto…
Education for Health Back at School Age: The Role of Physical Education
2015
Traditionally, back problems have been addressed from the biomedical area. For a long time the "radiologic-anatomy model" has been considered unusable because they have failed to respond to knowledge about the source of pain or therapeutic approaches used have solved the reduced chronic pain or disability [1]. In this way, it was like the biomedical reductionist approach was replaced by the "biopsychosocial model" [1] which proposes that psychological and social factors along with biological variables in understanding a person's disease are included.
Serous Macular Detachment Associated with Dome-Shaped Macula and Tilted Disc
2011
Introduction: An entirely new type of staphyloma has been recently described as dome-shaped macula (DSM). It is characterized by an abnormal convex macular contour within the concavity of a posterior staphyloma. We found DSM associated with serous macular detachment (SMD) and tilted disc in two consecutive cases. Case Reports: Case 1: A 37-year-old female presented to our department because of sudden onset blurred vision in her right eye (OD). The best-corrected visual acuity (BCVA) was 0.5 in both eyes. Funduscopy evidenced bilateral tilted disc associated with posterior staphyloma. Optical coherence tomography (OCT) demonstrated a DSM with SMD in her OD. After 15 months of follow-up, BCVA…