Search results for "LUDI"
showing 10 items of 753 documents
Terrestrial Inputs Drive Seasonality in Organic Matter and Nutrient Biogeochemistry in a High Arctic Fjord System (Isfjorden, Svalbard)
2020
Climate-change driven increases in temperature and precipitation are leading to increased discharge of freshwater and terrestrial material to Arctic coastal ecosystems. These inputs bring sediments, nutrients and organic matter (OM) across the land-ocean interface with a range of implications for coastal ecosystems and biogeochemical cycling. To investigate responses to terrestrial inputs, physicochemical conditions were characterized in a river- and glacier-influenced Arctic fjord system (Isfjorden, Svalbard) from May to August in 2018 and 2019. Our observations revealed a pervasive freshwater footprint in the inner fjord arms, the geochemical properties of which varied spatially and seaso…
IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia
2021
Simple Summary Although the prognosis of acute lymphoblastic leukemia (ALL) has improved significantly during the past decades, ALL remains a major cause of pediatric cancer mortality, and more accurate risk-stratification is required. We investigated IGF2BP3, which has previously been associated with aggressive cancers, and found high and subtype-specific expression of IGF2BP3 in B-cell ALL, that was associated with good outcome in high-risk patients. Results suggest that IGF2BP3 could be useful to improve stratification and prognosis of B-ALL. Abstract The oncofetal protein insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) belongs to a family of RNA-binding proteins involved i…
Empīriskās ticamības funkcija kodolu gludināšanas metodēm
2020
Maģistra darbā aplūkota varbūtību blīvuma funkcijas un neparametriskās regresijas funkcijas novērtēšana ar kodolu gludināšanas un empīriskās ticamības funkcijas metodēm. Darbā tika veikta simulāciju izpēte, kas parāda, ka empīriskās ticamības funkcijas metode labi darbojas blīvuma funkcijas un regresijas funkcijas novērtēšanā un dod labus rezultātus pārklājuma precizitātei. Darba gaitā tika paradītī praktiski lietojumi bioloģisko populāciju skaita un blīvuma novērtēšanā un bioloģisko datu regresijas analīzē. Definēta empīriskās ticamības funkcijas pielietošana, kad ir pieejama papildus informācija par populācijas sadalījumu. Doti nepieciešamie algoritmi kodolu gludināšanas un empīriskās tic…
Macroalgal responses to ocean acidification depend on nutrient and light levels
2015
Ocean acidification may benefit algae that are able to capitalize on increased carbon availability for photosynthesis, but it is expected to have adverse effects on calcified algae through dissolution. Shifts in dominance between primary producers will have knock-on effects on marine ecosystems and will likely vary regionally, depending on factors such as irradiance (light vs. shade) and nutrient levels (oligotrophic vs. eutrophic). Thus experiments are needed to evaluate interactive effects of combined stressors in the field. In this study, we investigated the physiological responses of macroalgae near a CO2 seep in oligotrophic waters off Vulcano (Italy). The algae were incubated in situ …
El pensament etiològic microbià i el paludisme (1880-1900)
2001
S'estudia l'evolució etiològica sobre el paludisme des de 1880 a 1990. Els vint anys estudiats permeten comprovar que la teoria miasmàtica que interpretava l'origen del paludisme va deixar pas a l'explicació microbiana causal sense a penes un altre canvi que la identificació del miasma palúdic amb l'hematozou de Laveran. Només el descobriment del mosquit anòfel com a vector de transmissió del paràsit va fer que se substituís la via respiratòria per la inoculació cutània com a mecanisme d'infecció. L’aire dels pantans no era ja el perjudicial, sinó les seues aigües estancades, el lloc on es criaven les larves dels mosquits, l'eliminació dels quals va convertir-se en el centre de la lluita an…
Análisis de las habilidades del manejo del grupo en un programa de educación afectivo-sexual para DFI
2021
Las habilidades de manejo de grupo que presenten los profesionales que imparten los programas de educación afectivo-sexual para personas con discapacidad intelectual son esenciales a fin de dirigir las sesiones hacia los objetivos establecidos. Por ello, el objetivo del presente trabajo es explorar las incidencias producidas durante la aplicación del Programa SALUDIVERSEX, en función del tipo de contenido de la sesión, analizando las habilidades de manejo del grupo de los 29 profesionales (90% mujeres y 10% hombres) que aplicaron este programa. Los resultados sugieren que las conductas inapropiadas de los/as usuarios/as son las incidencias más frecuentes tanto en las sesiones que trabajan h…
Spontaneous Music-Evoked Autobiographical Memories in Individuals Experiencing Depression
2020
Listening to music often triggers strong memories of events from our past, which influence how we affectively experience music listening and can therefore contribute to music’s therapeutic capacity. The aim of this study was to examine the valence and content of spontaneous music-evoked autobiographical memories (MEAMs) in listeners with self-reported depression, who typically demonstrate negatively biased autobiographical memory. Eighteen depressed and 21 controls participated in a music-listening experiment where they listened to a personalized music stimulus, described their memories, and thereafter rated the valence of these memories and of their induced affect. Participants’ ratings w…
Resultados preliminares de la eficacia del programa saludiversex de educación afectivo-sexual para adultos con diversidad funcional intelectual
2021
Para promover un desarrollo sexual saludable es necesario garantizar el acceso de las personas con discapacidad intelectual (PDI) a la formación en relación con sexualidad y las relaciones interpersonales. En este sentido, se precisan programas de educación afectivo sexual para PDI que presenten evidencias empíricas sólidas acerca de su validez. Con este objetivo, el presente estudio ofrece los datos preliminares sobre la eficacia de cuatro de las sesiones del Programa de Educación Afectivo-Sexual SALUDIVERSEX: (1) Higiene íntima, (2) Abuso sexual, (3) Orientación sexual e (4) Intimidad. El programa fue aplicado a 43 usuarios de cuatro centros ocupacionales de la Comunitat Valenciana. La im…
Accurate Triage of Oncological Patients for Safely Continuing Cancer Therapy During the SARS-CoV-2 Pandemic
2021
ObjectiveTo evaluate the efficacy of clinical triage of oncological patients for safe continuation of cancer therapy implemented during the first SARS-CoV-2 outbreak.MethodsBetween 25 February and 21 April 2020, patients attending the Medical Oncology Unit, Spedali Civili Hospital, Brescia (Italy) for cancer therapy underwent triage to identify those with no signs and symptoms suspicious for SARS-CoV-2 infection in which antineoplastic treatment could be continued as scheduled. Triage questions investigated common symptoms (e.g., fever, cough, dyspnea, anosmia, dysgeusia, headache, nasal congestion, conjunctival congestion, sore throat, diarrhea, nausea and vomiting); body temperature and p…
Transperitoneal vs retroperitoneal minimally invasive partial nephrectomy: comparison of perioperative outcomes and functional follow-up in a large m…
2020
Abstract Background Aim of this study was to evaluate and compare perioperative outcomes of transperitoneal (TP) and retroperitoneal (TR) approaches in a multi-institutional cohort of minimally invasive partial nephrectomy (MI-PN). Material and methods All consecutive patients undergone MI-PN for clinical T1 renal tumors at 26 Italian centers (RECORd2 project) between 01/2013 and 12/2016 were evaluated, collecting the pre-, intra-, and postoperative data. The patients were then stratified according to the surgical approach, TP or RP. A 1:1 propensity score (PS) matching was performed to obtain homogeneous cohorts, considering the age, gender, baseline eGFR, surgical indication, clinical dia…