Search results for "LYN"
showing 10 items of 910 documents
A CNN Adaptive Model to Estimate PM10 Monitoring
2006
In this work we introduce a model for studying the distribution and control of atmospheric pollution from PM10. The model is based on the use of a cellular neural network (CNN) and more precisely on the integration of the mass-balance equation; at the same time it simulates the scenario regarding a planar grid describing the whole studied area (the city of Palermo) by means of a CNN and a set of Bayesian networks. The CNN allows us to define a grid system whose dynamic evolution is a redefinition of the diffusion equation that considers contributions coming from near cells for each element of the grid. Dynamics of each cell is influenced by meteorological effects and by parameters related t…
Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis
2022
Simple Summary International guidelines recommend universal screening of endometrial carcinoma patients for Lynch syndrome, a hereditary cancer predisposition syndrome. Screening is based on mismatch repair protein immunohistochemistry and reflex MLH1 methylation analysis to exclude the likely sporadic cases of MMR deficiency. As sporadic MLH1 protein loss is common in endometrial carcinoma, the ability to target methylation testing would save efforts and costs. We discovered that limiting methylation testing to patients under 65 years would have significantly reduced the testing effort while maintaining a low false negative rate for MLH1-LS detection (0% and 3% in our clinic and registry-b…
Lynchin oireyhtymän syöpää ehkäisevä seuranta muuttuu geenikohtaiseksi
2020
Asetyylisalisyylihapon tehosta vakuuttavaa näyttöä ja rokote kehitteillä nonPeerReviewed
On Prefix Normal Words
2011
We present a new class of binary words: the prefix normal words. They are defined by the property that for any given length $k$, no factor of length $k$ has more $a$'s than the prefix of the same length. These words arise in the context of indexing for jumbled pattern matching (a.k.a. permutation matching or Parikh vector matching), where the aim is to decide whether a string has a factor with a given multiplicity of characters, i.e., with a given Parikh vector. Using prefix normal words, we give the first non-trivial characterization of binary words having the same set of Parikh vectors of factors. We prove that the language of prefix normal words is not context-free and is strictly contai…
Is HLA type a possible cancer risk modifier in Lynch syndrome?
2022
Lynch syndrome (LS) is the most common inherited cancer syndrome. It is inherited via a monoallelic germline variant in one of the DNA mismatch repair (MMR) genes. LS carriers have a broad 30-80% risk of developing various malignancies, and more precise, individual risk estimations would be of high clinical value, allowing tailored cancer prevention and surveillance. Due to MMR deficiency, LS cancers are characterized by the accumulation of frameshift mutations leading to highly immunogenic frameshift peptides (FSPs). Thus, immune surveillance is proposed to inhibit the outgrowth of MMR-deficient cell clones. Recent studies have shown that immunoediting during the evolution of MMR-deficient…
Codimensions of algebras with additional structures
2022
Let A be an associative algebra endowed with an automorphism or an antiautomorphism phi of order <= 2. One associates to A, in a natural way, a numerical sequence c(n)(phi)(A), n = 1, 2, ... , called the sequence of phi-codimensions of A which is the main tool for the quantitative investigation of the polynomial identities satisfied by A. In [13] it was proved that such a sequence is eventually nondecreasing in case phi is an antiautomorphism. Here we prove that it still holds in case phi is an automorphism and present some recent results about the asymptotics of c(n)(phi)(A).
Sensory analysis integrated by palynological and physicochemical determinations plays a key role in differentiating unifloral honeys of similar botan…
2015
Summary Myrtaceae honeys produced in Sierra Morena (southern Spain, Andalusia) are obtained from both Eucalyptus camaldulensis and Myrtus communis, and honeys can be easily confused when classified as they come from the same botanical family. The characterisation was intended on the basis of their physicochemical, sensory and palynological properties. Cluster analysis (CA) and principal component analysis (PCA) allowed us to make a distinction between two honey profiles. The first one corresponds to the European sensory profile described for Eucalyptus unifloral honeys. The second profile, which sensory characteristics are absolutely different, has not been previously described. Classificat…
Angular specifiska TypeScript pirmkoda ģenerēšana ar Roslyn .NET kompilatora platformu
2017
Modernos tīmekļa risinājumos datu modelis tiek dublēts starp servera un klienta lietotnēm. Šo informāciju vajag uzturēt atbilstošu abos galos - mainoties datu modelim, izmaiņas vajag atspoguļot gan servera, gan klienta pusē (kas atbilst dažādām izpildes vidēm un dažādām programmēšanas valodām). Lai izvairītos no manuālās izmaiņu sinhronizācijas, darbā tiek aplūkota pirmkoda ģenerēšanas pieeja, kas ļauj šo procesu automatizēt. Darbā identificēti dublētie informācijas vienumi tieši ASP.NET (servera pusē) un Angular (klienta pusē) tīmekļa risinājumos, izpētīti esošie problēmas risinājumi, kas veic pirmkoda ģenerēšanu, kā arī izpētītas .NET pirmkoda analīzes un TypeScript pirmkoda ģenerēšanas i…
Polityczne spory o upamiętnienie zbrodni na Wołyniu w polskim parlamencie
2014
Celem artykułu jest ukazanie dyskursu o upamiętnieniu zbrodni wołyńskiej na forum parlamentu III RP. Praca oparta została o analizę materiałów pochodzących bezpośrednio z polskiego parlamentu, takich jak: sprawozdania stenograficzne z posiedzeń Sejmu, sprawozdania stenograficzne z posiedzeń sejmowych komisji, ale również o doniesienia medialne, publikowane w Internecie i prasie codziennej. Tekst otwiera synteza polskich debat nad samym zagadnieniem polityki historycznej oraz komparatystyka jej dwóch dominujących na przełomie XX i XXI w. nurtów: liberalnego i konserwatywnego. W dalszej części autor skrótowo przedstawia poglądy władz ukraińskich w okresie 1991-2014 na kwestię antypolskich dzi…
Embeddings of Danielewski hypersurfaces
2008
In this thesis, we study a class of hypersurfaces in $\mathbb{C}^3$, called \emph{Danielewski hypersurfaces}. This means hypersurfaces $X_{Q,n}$ defined by an equation of the form $x^ny=Q(x,z)$ with $n\in\mathbb{N}_{\geq1}$ and $\deg_z(Q(x,z))\geq2$. We give their complete classification, up to isomorphism, and up to equivalence via an automorphism of $\mathbb{C}^3$. In order to do that, we introduce the notion of standard form and show that every Danielewski hypersurface is isomorphic (by an algorithmic procedure) to a Danielewski hypersurface in standard form. This terminology is relevant since every isomorphism between two standard forms can be extended to an automorphism of the ambiant …