Search results for "Laboratori"
showing 10 items of 390 documents
Short time guided bone regeneration using beta-tricalcium phosphate with and without fibronectin. An experimental study in rats
2020
Background The aim of this histomorphometric study was to assess the bone regeneration potential of beta-tricalcium phosphate with fibronectin (β-TCP-Fn) in critical-sized defects (CSDs) in rats calvarial, to know whether Fn improves the new bone formation in a short time scope. Material and Methods CSDs were created in 30 Sprague Dawley rats, and divided into four groups (2 or 6 weeks of healing) and type of filling (β-TCP-Fn, β-TCP, empty control). Variables studied were augmented area (AA), gained tissue (GT), mineralized/non mineralized bone matrix (MBM/NMT) and bone substitute (BS). Results 60 samples at 2 and six weeks were evaluated. AA was higher for treatment groups comparing to …
Calidad, Validación de métodos, Control de calidad, Incertidumbre, Acreditación de laboratorios
2010
Describir e ilustrar con un ejemplo el procedimiento a seguir para armonizar tres procesos internos de calidad, relacionados con un método de análisis, en el laboratorio de ensayo, LE: Validación de la exactitud, Control de calidad y Expresión de la incertidumbre. Además, la Guía se ha diseñado para que el usuario (estudiante o profesional) alcance competencias y cualificación suficiente para ejecutar correctamente un documento del sistema de calidad del LE y poder cumplimentar un registro de validación de manera conforme. Finalmente, la Guía (en sí misma, junto al resto de documentos que la componen) pretende servir de orientación didáctica al usuario sobre algunos aspectos clave de un sis…
Le camere riverberanti presso il laboratorio di acustica dell’Università di Palermo
2010
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids
2021
AbstractThe prognosis of locally advanced colorectal cancer (CRC) is currently unsatisfactory. This is mainly due to drug resistance, recurrence, and subsequent metastatic dissemination, which are sustained by the cancer stem cell (CSC) population. The main driver of the CSC gene expression program is Wnt signaling, and previous reports indicate that Wnt3a can activate p38 MAPK. Besides, p38 was shown to feed into the canonical Wnt/β-catenin pathway. Here we show that patient-derived locally advanced CRC stem cells (CRC-SCs) are characterized by increased expression of p38α and are “addicted” to its kinase activity. Of note, we found that stage III CRC patients with high p38α levels display…
La casa ipertestuale. Libertà e complessità nell'abitare
2008
L'articolo fa riferimento, in generale, all’esperienza del workshop "Futura, come abiteremo domani" che ha avuto luogo nei laboratori della Facoltà di Architettura di Palermo nel marzo del 2005. Iniziativa nata da una sollecitazione di Lucio Dalla ed in collaborazione con Expa, galleria di Architettura. Al workshop hanno partecipato studenti della facoltà provenienti dai corsi di laurea in Architettura 4/s e Disegno Industriale, e si è articolato in sei laboratori diretti dai professori Teresa La Rocca (coordinatore), Emanuele Palazzotto, Marcello Panzarella, Michele Sbacchi, Andrea Sciascia, Viviana Trapani. In particolare, il tema di progetto affrontato all’interno del Laboratorio del Pro…
Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
2023
Abstract Background Colorectal cancer (CRC) can be divided into four consensus molecular subtypes (CMS), each with distinct biological features. CMS4 is associated with epithelial-mesenchymal transition and stromal infiltration (Guinney et al., Nat Med 21:1350–6, 2015; Linnekamp et al., Cell Death Differ 25:616–33, 2018), whereas clinically it is characterized by lower responses to adjuvant therapy, higher incidence of metastatic spreading and hence dismal prognosis (Buikhuisen et al., Oncogenesis 9:66, 2020). Methods To understand the biology of the mesenchymal subtype and unveil specific vulnerabilities, a large CRISPR-Cas9 drop-out screen was performed on 14 subtyped CRC cell lines to un…
Il laboratorio di chimica
2001
Analysis of trichothecenes in laboratory rat feed by gas chromatography-tandem mass spectrometry
2015
A method for the determination of seven trichothecenes, neosolaniol (NEO), diacetoxyscirpenol (DAS), deoxynivalenol (DON), nivalenol (NIV), fusarenon-X (FUS-X), 3-acetyldeoxynivalenol (3-ADON) and 15-acetyldeoxynivalenol (15-ADON), in laboratory rat feed by GC-MS/MS was developed. Sample extraction and purification was performed by an acidified mixture of acetonitrile/water (80-20% v/v). Limits of quantitation (LOQs) were between 1 and 10 μg kg(-1) for all studied trichothecenes. Eight concentration levels between the LOQ and 100 × LOQ were used for the calibration curves. Matrix-matched calibration was used for quantitation purposes to compensate the detector signal enhancement obtained fo…
Progetti in Fiera. Progetti urbani degli studenti del Laboratorio di Progettazione Architettonica 2°
2012
La recensione riguarda il libro di Antonio Marino (con Francesco Messina) intitolato "Progetti in Fiera", Liriti Editore, Reggio Calabria (2010). Si tratta di una pubblicazione degli esiti dei Laboratori di Progettazione Architettonica 2° della Facoltà di Reggio Calabria, del Prof. Nino Marino, che ha scelto, per tre anni consecutivi, a partire dall'a.a. 2005-2006, la cittadella Fieristica messinese quale campo di applicazione privilegiato di sperimentazione didattica.
Laboratorio I di Progettazione Architettonica
2014
Il breve saggio definisce le linee guida della didattica della progettazione architettonica del I anno specificandone gli obbiettivi, i contenuti e le finalità.