Search results for "Ladder"

It is time to abandon “Expected bladder capacity.” Systematic review and new models for children's normal maximum voided volumes

2013

Background There is an agreement to use simple formulae (expected bladder capacity and other age based linear formulae) as bladder capacity benchmark. But real normal child's bladder capacity is unknown. Aims To offer a systematic review of children's normal bladder capacity, to measure children's normal maximum voided volumes (MVVs), to construct models of MVVs and to compare them with the usual formulae. Methods Computerized, manual and grey literature were reviewed until February 2013. Epidemiological, observational, transversal, multicenter study. A consecutive sample of healthy children aged 5–14 years, attending Primary Care centres with no urologic abnormality were selected. Particip…

Validation of Fenoterol to Study β<sub>2</sub>-Adrenoceptor Function in the Rat Urinary Bladder

2021

Fenoterol is a β<sub>2</sub>-adrenoceptor (AR)-selective agonist that is commonly used to investigate relaxation responses mediated by β<sub>2</sub>-AR in smooth muscle preparations. Some data have questioned this because fenoterol had low potency in the rat urinary bladder when a muscarinic agonist was used as a pre-contraction agent and because some investigators proposed that fenoterol may act in part via β<sub>3</sub>-AR. We designed the present study to investigate whether fenoterol is a proper pharmacological tool to study β<sub>2</sub>-AR-mediated relaxation responses in the rat urinary bladder. Firstly, we have compared the effect of p…

Are morphology and composition of gallstones related? An x-ray diffraction study

1994

Abstract An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile…

2005

Ethanol inhibits proliferation in astrocytes, an effect that was recently linked to the suppression of phosphatidic acid (PA) formation by phospholipase D (PLD). The present study investigates ethanol's effect on the induction of apoptosis in astrocytes and the formation of ceramide, an apoptotic signal. Evidence is presented that the formation of PA and ceramide may be reciprocally linked during ethanol exposure. In cultured rat cortical astrocytes, ethanol (0.3–1 %, v/v) induced nuclear fragmentation and DNA laddering indicative of apoptosis. Concomitantly, in cells prelabeled with [3H]-serine, ethanol caused a dose-dependent, biphasic increase of the [3H]-ceramide/ [3H]-sphingomyelin rat…

Oral trasmucosal fentanyl citrate for breakthrough pain treatment in cancer patients.

2012

Breakthrough cancer pain has been defined as a transitory increase in pain intensity that occurs either spontaneously or in relation to a specific predictable or unpredictable trigger, despite relatively stable and adequately controlled background pain. The availability of supplemental doses of oral opioids, in addition to the continuous analgesic medication, is the main treatment suggested to manage pain flares.Oral transmucosal fentanyl citrate (OTFC) is the first product of a new generation of delivery systems, named rapid-onset opioids (ROOs), characterized by rapidity of effect and the short duration of analgesia. Controlled studies and long-term experience have shown that OTFC is an e…

Authors' response to Hermann et al. Minimum quality criteria are needed in the assessment and communication of unexpected drug safety findings of mar…

2012

Hermann et al. [1] suggest that minimum quality criteria are needed to communicate unexpected drug safety findings from randomized clinical trials and imply that our report on unexpected frequent hepatotoxicity in patients receiving flupirtine for the treatment of overactive bladder syndrome [2] does not meet such criteria. As the brief report format of our paper did not allow an extensive description of trial details, we welcome this opportunity to shed more light on the matter.

Some remarks on few recent results on the damped quantum harmonic oscillator

2020

Abstract In a recent paper, Deguchi et al. (2019), the authors proposed an analysis of the damped quantum harmonic oscillator in terms of ladder operators. This approach was shown to be partly incorrect in Bagarello et al. (2019), via a simple no-go theorem. More recently, (Deguchi and Fujiwara, 2019), Deguchi and Fujiwara claimed that our results in Bagarello et al. (2019) are wrong, and compute what they claim is the square integrable vacuum of their annihilation operators. In this brief note, we show that their vacuum is indeed not a vacuum, and we try to explain what is behind their mistakes in Deguchi et al. (2019) and Deguchi and Fujiwara (2019). We also propose a very simple example …

Closure relations during the plateau emission of Swift GRBs and the fundamental plane

2021

The Neil Gehrels Swift observatory observe Gamma-Ray bursts (GRBs) plateaus in X-rays. We test the reliability of the closure relations through the fireball model when dealing with the GRB plateau emission. We analyze 455 X-ray lightcurves (LCs) collected by \emph{Swift} from 2005 (January) until 2019 (August) for which the redshift is both known and unknown using the phenomenological Willingale 2007 model. Using these fits, we analyze the emission mechanisms and astrophysical environments of these GRBs through the closure relations within the time interval of the plateau emission. Finally, we test the 3D fundamental plane relation (Dainotti relation) which connects the prompt peak luminosi…

EXTRACTION OF INFRARED DIVERGENCES IN THE DIMENSIONAL REGULARIZED TWO-LOOP LADDER GRAPH

1994

We consider the evaluation of the fundamental scalar integral in the on-shell two-loop ladder graph with different external masses and arbitrary transfer momentum. A method for cleanly extracting the infrared divergences in the Feynman parameter integrals using dimensional regularization is presented, and we analyze one of the finite part contributions to this integral.

Susy for non-Hermitian Hamiltonians, with a view to coherent states

2020

We propose an extended version of supersymmetric quantum mechanics which can be useful if the Hamiltonian of the physical system under investigation is not Hermitian. The method is based on the use of two, in general different, superpotentials. Bi-coherent states of the Gazeau-Klauder type are constructed and their properties are analyzed. Some examples are also discussed, including an application to the Black-Scholes equation, one of the most important equations in Finance.