Search results for "Lag"

Más allá de Vainica Doble: Carmen Santonja, pintora

2009

Este artículo analiza la trayectoria pictórica de Carmen Santonja (Madrid, 1934- 2000). Aunque ha sido más conocida como cantante, ya que formó parte del célebre grupo Vainica Doble, C. Santonja también se dedicó con intensidad a otras disciplinas artísticas cine, televisión , destacando especialmente su vocación pictórica. Sus obras, como su música, reflejarán el gusto por la naturaleza dentro de una estética pop, mostrando gran interés por la experimentación, que le llevará a la creación de nuevas técnicas, como el decollage. (A)

Capparis tchaourembensis, a new species of Capparaceae from Mayotte, Comororian Archipelago

2011

A new species of Capparis, C. tchaourembensis Fici, is described and illustrated. Its conservation status is assessed and its affinities with related taxa are discussed.

Collecting evidence for a stem cell hypothesis in HCC.

2010

Ever since Ernest McCulloch and James E Till defined essential stem cell properties, the field of stem cell biology has attracted increasing interest.1 Manipulating embryonic stem cells has resulted in advanced genetic technologies such as knock-out and transgenic animals, providing valuable models to study genetic influence on a wide variety of diseases.2 The success in manipulating stem cells and the ability to differentiate them into diverse tissues brought with them countless concepts of utilising stem cells in medicine. The idea of perpetually dividing pluripotent cells, capable of differentiating into nearly every possible cell or tissue type, seems like an inexhaustible resource for …

Procollagen C-Proteinase Enhancer 1 (PCPE-1) is a marker of myocardial fibrosis and impaired cardiac function in a murine model of pressure overload

2021

Abstract(1)AimsProcollagen C-proteinase enhancer 1 (PCPE-1) is an extracellular matrix protein and a major regulator of fibrillar collagen biosynthesis. Previous work has shown that its abundance is often increased in the context of tissue repair and fibrosis. The present study was designed to evaluate its potential as a biomarker of myocardial interstitial fibrosis (MIF), a well-established pathogenic pathway leading to heart failure.(2)Methods and ResultsCardiac fibrosis was induced in rats using an optimized model of chronic pressure overload triggered by angiotensin II and Nω-nitro-L-arginine methyl ester (L-NAME). All treated animals suffered from heart hypertrophy and the increase in …

Epicardial delivery of collagen patches with adipose-derived stem cells in rat and minipig models of chronic myocardial infarction.

2013

Although transplantation of adipose-derived stem cells (ADSC) in chronic myocardial infarction (MI) models is associated with functional improvement, its therapeutic value is limited due to poor long-term cell engraftment and survival. Thus, the objective of this study was to examine whether transplantation of collagen patches seeded with ADSC could enhance cell engraftment and improve cardiac function in models of chronic MI. With that purpose, chronically infarcted Sprague-Dawley rats (n = 58) were divided into four groups and transplanted with media, collagen scaffold (CS), rat ADSC, or CS seeded with rat ADSC (CS-rADSC). Cell engraftment, histological changes, and cardiac function were …

Carta Pastoral de ... Alonso de Santo Tomas Obispo de Malaga ... a los fieles de su Obispado exortandolos à hazimientos de gracias, en ocasion del tr…

Sign.: []1, A-F2 Postil·les marginals

Deguna vārstules aktivitātes novērtējums, izmantojot 4 fāžu rinamometru. Jauna parametra ieviešana un statistiskais novērtējums

2017

Darba mērķis: jauna parametra (deguna vārstules indeksa) izpēte, identificējot cilpas rinomanometriskajās līknēs kā deguna vārstules aktivitāties pazīmi. Skaitliski novērtēt rinomanometrijas cilpu nozīmi ar deguna vārstules indeksa palīdzību. Materiāli un metodes: rinomanometrijas dati tika iegūti no 250 pacientiem (veicot aktīvas priekšējās rinomanometrijas mērījumus), ar rinomanometru 4RHINO (RhinolabGermany), programmatūras versijā 4.31 un 5.01. Mērījumi tika veikti pirms dekongestantu lietošanas un pēc dekongestantu lietošanas, atkārtojot mērījumus pēc 10 minūtēm. Deguna vārstules indekss tika atlasīts un pievienots "HRR-Export-file". Statistiskajai analīzei tika izmantots Microsoft Off…

In vitro 30 nm silver nanoparticles promote chondrogenesis of human mesenchymal stem cells

2015

Silver nanoparticles (Ag NPs) are one of the most widely used products in nano-medicine due to their broad-spectrum antimicrobial activity. In tissue engineering, Ag NPs are often incorporated as antibacterial agents in scaffolds, which are subsequently loaded with human bone marrow-derived mesenchymal stem cells (hMSCs). In this study, we investigated the effect of Ag NPs on chondrogenesis of hMSCs. The synthesized Ag NPs were spherical in shape, with a mean diameter of ∼30 nm. After 24 h exposure, Ag NPs were taken up into hMSCs and mainly distributed in the cytoplasm, the nucleus and different sized vesicles. We examined the chondrogenesis through several methods, including glycosaminogl…

Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage

2011

SummaryObjectiveThe effect of threose-induced collagen cross-linking on the mechanical and diffusive properties of cartilage was investigated in vitro. In particular, we investigated the potential of Contrast Enhanced Computed Tomography (CECT) to detect changes in articular cartilage after increased collagen cross-linking, which is an age-related phenomenon.MethodsOsteochondral plugs (Ø=6.0mm, n=28) were prepared from intact bovine patellae (n=7). Two of the four adjacent samples, prepared from each patella, were treated with threose to increase the collagen cross-linking, while the other two specimen served as paired controls. One sample pair was mechanically tested and then mechanically …

Volumetric changes of articular cartilage during stress relaxation in unconfined compression

2000

The time-dependent lateral expansion and load relaxation of cartilage cylinders subjected to unconfined compression were simultaneously recorded. These measurements were used to (1) test the assumption of incompressibility for articular cartilage, (2) measure the Poisson's ratio of articular cartilage in compression and (3) investigate the relationship between stress relaxation and volumetric change. Mechanical tests were performed on fetal, calf, and adult humeral head articular cartilage. The instantaneous Poisson's ratio of adult cartilage was 0.49+/-0.08 (mean+S.D.), thus confirming the assumption of incompressibility for this tissue. The instantaneous Poisson's ratio was significantly …