Search results for "Lagomorpha"

showing 5 items of 25 documents

Changes in the motility patterns of spermatozoa from the rabbit epididymis as assessed by computer-aided sperm motion analysis

1996

Sperm maturation in the epididymis includes changes in their potential for motility that enables spermatozoa to reach the egg and penetrate its investments. The motility characteristics of spermatozoa from the testis, the epididymis, and vas deferens of the rabbit were investigated by computer-assisted sperm analysis (CASA). Various forms of motility were displayed by sperm from different regions of the epididymis released into incubation medium. Testicular sperm were motile, although nonprogressive. The maximum percentage motility was expressed by sperm in the proximal cauda epididymidis, and forward progression was developed by spermatozoa from the distal caput. Once forward progression w…

endocrine systemLagomorphaurogenital systemVas deferensMotilityCell BiologyAnatomyTesticleBiologybiology.organism_classificationEpididymisSpermLateral displacementAndrologymedicine.anatomical_structureGeneticsmedicineIncubationreproductive and urinary physiologyDevelopmental BiologyMolecular Reproduction and Development
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Effects on lipoprotein subclasses of combined expression of human hepatic lipase and human apoB in transgenic rabbits

2003

Objective— The effects of combined expression of human hepatic lipase (HL) and human apolipoprotein B (apoB) on low-density lipoprotein (LDL) subclasses were examined in rabbits, a species naturally deficient in HL activity. Methods and Results— In apoB-transgenic rabbit plasma, >80% of the protein was found in the 1.006- to 1.050-g/mL fraction. Gradient gel electrophoresis (GGE) of this fraction revealed two distinct species, designated large and small LDL. A denser fraction (d=1.050 to 1.063 g/mL) contained small LDL as well as another discrete LDL subspecies, designated very small LDL. Expression of HL resulted in reductions in protein concentrations in the 1.006- to 1.050-g/mL densi…

medicine.medical_specialtyApolipoprotein BRecombinant Fusion ProteinsTriacylglycerol lipaseAnimals Genetically ModifiedSpecies SpecificityInternal medicineCentrifugation Density GradientmedicineAnimalsHumansTriglyceridesApolipoproteins BGel electrophoresischemistry.chemical_classificationLagomorphabiologyLipasebiology.organism_classificationAnimal FeedSpecific Pathogen-Free OrganismsLipoproteins LDLMolecular WeightEndocrinologyEnzymechemistrybiology.proteinElectrophoresis Polyacrylamide GelFemalelipids (amino acids peptides and proteins)Density gradient ultracentrifugationRabbitsHepatic lipaseCardiology and Cardiovascular MedicineLipoprotein
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Analysis of Rabbit Vascular Responses to DBI, an Ingol Derivative Isolated from Euphorbia canariensis

1997

Abstract We have analysed the effects of 7,12-O-diacetyl-8-O-benzoil-2,3-diepiingol (DBI), an ingol derivative isolated from E. canariensis, on isometric tension developed by isolated rabbit basilar and carotid arteries. Concentration-response curves to DBI (10−8 - 3 × 10−5 m) were obtained cumulatively in both arteries at resting tension and active tone (KC1, 50 mm). At resting tension, DBI induced a concentration-dependent contraction, which was not inhibited in Ca2+-free medium. H7 (1-(5-isoquinoline sulphonyl)-2-methylpiperazine dichloride) (10−4 m) inhibited the DBI-induced contraction both in basilar and in carotid arteries. Calmidazolium (10−4 m) inhibited the maximum contraction of …

medicine.medical_specialtyContraction (grammar)LatexCarotid Artery CommonMuscle RelaxationPharmaceutical ScienceProstacyclinNitric OxideNitroarginineMuscle Smooth VascularEuphorbia canariensisCalmodulin1-(5-Isoquinolinesulfonyl)-2-MethylpiperazineInternal medicinemedicine.arterymedicineBasilar arteryAnimalsEnzyme InhibitorsProtein Kinase CPharmacologyPlants MedicinalLagomorphabiologyPlant Extractsbiology.organism_classificationEpoprostenolEndocrinologymedicine.anatomical_structureBasilar ArteryCirculatory systemcardiovascular systemCalciumRabbitsDiterpenesMuscle Contractionmedicine.drugBlood vesselArteryJournal of Pharmacy and Pharmacology
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Effects of intermittent high frequency electrical stimulation on denervated EDL muscle of rabbit.

1990

This study was performed to determine whether electrical stimulation can retard denervation-induced changes. The denervated extensor digitorum longus of the rabbit, a fast-twitch muscle, was stimulated at a rate mimicking its motoneuron firing pattern. The 100-Hz stimulation given intermittently subjected the muscle to a low mean total daily frequency of 1.6 Hz. Four weeks of stimulation resulted in no effect upon the denervated stimulated muscle. This stimulation protocol, therefore, is unable to substitute for the lost neuronal influence of the nerve. The muscle contralateral to the stimulated side showed physiological changes making it unsuitable to serve as a control.

medicine.medical_specialtyPhysiologyStimulationCellular and Molecular NeuroscienceAtrophyPhysiology (medical)Internal medicinemedicineAnimalsDenervationContraction timeLagomorphabiologyChemistryElectromyographyMusclesAnatomymusculoskeletal systembiology.organism_classificationmedicine.diseaseAmyotrophyElectric StimulationMuscle DenervationMuscular AtrophyEndocrinologyNeurology (clinical)RabbitsMuscle ContractionMusclenerve
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Newborn rabbit responsiveness to the mammary pheromone is concentration-dependent.

2004

The effect of the intensity of odour signals has rarely been investigated in the regulation of odour-guided behaviour in young mammals. This series of experiments used the mammary pheromone (MP) of the female rabbit to assess the influence of stimulus concentration on neonatal pup responsiveness. The MP is a single compound isolated from rabbit milk that releases in pups the typical head searching and oral seizing behaviour. The pups (n = 621) were exposed to graded concentrations of the MP in bioassays varying in stimulus delivery conditions. Experiment 1 demonstrated that in aqueous dilutions the MP efficiently elicits behavioural responses only within a limited range of concentrations (f…

medicine.medical_specialtySerial dilutionPhysiologyStimulationOlfactionBiologyBreast milkPheromonesBehavioral NeuroscienceMammary Glands AnimalPregnancyPhysiology (medical)Internal medicinemedicineBioassayAnimalsComputingMilieux_MISCELLANEOUSLagomorphaDose-Response Relationship DrugFeeding BehaviorOlfactory Pathwaysbiology.organism_classificationSensory SystemsDose–response relationshipEndocrinologyMilkAnimals Newborn[CHIM.OTHE] Chemical Sciences/OtherRELATION MERE-ENFANTPheromoneFemaleRabbits[CHIM.OTHE]Chemical Sciences/OtherChemical senses
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