Search results for "Lamb"

ModEst - Precise estimation of genome size from NGS data

2021

AbstractPrecise estimates of genome sizes are important parameters for both theoretical and practical biodiversity genomics. We present here a fast, easy-to-implement and precise method to estimate genome size from the number of bases sequenced and the mean sequence coverage. To estimate the latter, we take advantage of the fact that a precise estimation of the Poisson distribution parameter lambda is possible from truncated data, restricted to the part of the coverage distribution representing the true underlying distribution. With simulations we could show that reasonable genome size estimates can be gained even from low-coverage (10X), highly discontinuous genome drafts. Comparison of es…

Engineering Topological Nodal Line Semimetals in Rashba Spin-Orbit Coupled Atomic Chains

2019

We study an atomic chain in the presence of modulated charge potential and modulated Rashba spin-orbit coupling (RSOC) of equal period. We show that for commensurate periodicities $\lambda=4 n$ with integer $n$, the three-dimensional synthetic space obtained by sliding the two phases of the charge potential and RSOC features a topological nodal line semimetal protected by an antiunitary particle-hole symmetry. The location and shape of the nodal lines strongly depend on the relative amplitude between the charge potential and RSOC.

Lambda Architecture pour une analyse à haute performance des données des réseaux sociaux

2019

In this article, we show how a Lambda Architecture can contribute to the development of a platform for collecting and analyzing, in real-time, data from Twitter. After having presented the context, detailed the needs and identified the expected specificities, we compare the Lambda and Kappa architectures and we describe the state of the art on Lambda Architecture use in different domains. We propose an adaptation of the Lambda architecture to allow the storage of data in a polystore and to take into account different types of analysis to be carried out to answer researches in social sciences and communication sciences. In these projects the objectives are to study the structure of communica…

Dynamics of gene regulatory networks and their dependence on network topology and quantitative parameters – the case of phage λ

2019

Background Gene regulatory networks can be modelled in various ways depending on the level of detail required and biological questions addressed. One of the earliest formalisms used for modeling is a Boolean network, although these models cannot describe most temporal aspects of a biological system. Differential equation models have also been used to model gene regulatory networks, but these frameworks tend to be too detailed for large models and many quantitative parameters might not be deducible in practice. Hybrid models bridge the gap between these two model classes – these are useful when concentration changes are important while the information about precise concentrations and binding…

Resolvent estimates for the magnetic Schrödinger operator in dimensions $$\ge 2$$

2019

It is well known that the resolvent of the free Schr\"odinger operator on weighted $L^2$ spaces has norm decaying like $\lambda^{-\frac{1}{2}}$ at energy $\lambda$. There are several works proving analogous high-frequency estimates for magnetic Schr\"odinger operators, with large long or short range potentials, in dimensions $n \geq 3$. We prove that the same estimates remain valid in all dimensions $n \geq 2$.

Restriction analysis of lambda EMBL3 background recombinants: occurrence of lambda phages carrying a head to tail oriented left arm DNA sequence.

1989

Eight representative recombinant background clones of lambda EMBL3 were analysed using KpnI, BamHI, SalI, EcoRI and HindIII digestion. We found that lambda EMBL3 carries its own left arm in the BamHI cloning site. In the way, recombinant molecules were found to be generated which can grow on Escherichia coli strain NM539. In all cases analysed, the left arm DNA was inserted in a head to tail orientation. Seven clones carried a restored BamHI site at the cos site-BamHI site connection. In the region where the inserted left arm and the right arm were ligated, BamHI cloning produces a large palindromic sequence consisting of two polylinkers. This BamHI site was incompletely cleaved in all case…

Duodenal Giardiasis: a diagnosis we should not neglect

2008

Secretin—cerulein test and fecal chymotrypsin concentration in children with intestinal giardiasis

1993

We studied six patients with giardiasis (five males, one female), median age 3.5 yr (range 1-11) and 12 healthy control subjects (10 males, 2 females), median age 3.5 yr (range 1-10). Intestinal biopsy and a contemporaneous secretin-cerulein test were performed in all patients, and fecal chymotrypsin was also assayed. Intestinal biopsy was normal in five of the six patients with giardiasis, whereas one of the six presented a partial atrophy of the intestinal villi. The secretin-cerulein test (1 CU/kg of secretin + 75 ng/kg of cerulein) did not show any significant difference between values in the outputs of chymotrypsin, lipase, phospholipase, and bicarbonate obtained in patients and in con…

Secondary impairment of pancreatic function as a cause of severe malabsorption in intestinal giardiasis: A case report

1997

We report the case of a 54-year-old male patient hospitalized for diarrhea and weight loss (8 kg over the previous three months). At admission, we observed pale oral and conjunctival mucosa and peripheral edema of the lower limbs. Stool frequency was 8-10 per day. Laboratory data were as follows: hemoglobin, 11 g/dL; total proteins, 4.3 g/dL; albumin, 2 g/dL; pseudocholinesterase, 1248 U/L; triglycerides, 54 mg/dL; serum cholesterol, 102 mg/dL; calcium, 7.9 mg/dL. Fecal fat was 8.2 g/24 hr. Fecal chymotrypsin (FCT) was 2.3 U/g. A duodenal probe was performed after administration of intravenous secretin and cerulein stimulation, and a contemporaneous mucosal biopsy was taken at the ligament …

Survey of the occurrence of Giardia duodenalis cysts and Cryptosporidium spp. oocysts in green leafy vegetables marketed in the city of Valencia (Spa…

2022

The role of vegetables usually consumed without prior culinary treatment is known to contribute to the prevalence of foodborne diseases. Cysts and oocysts can contaminate food, which can then be the source of infection in humans. The aim of the study was to assess the occurrence of Giardia duodenalis and Cryptosporidium spp. (oo) cysts in green leafy vegetables marketed in the city of Valencia (Spain) combining parasitological methods, two real-time qPCRs and light microscopy. An experimental field study was conducted on 129 vegetable samples, 64 from conventional farms and 65 from ecological (organic) farms. The samples were washed with water, and the resulting solution after removing the …