Search results for "Lament"
showing 10 items of 895 documents
Identità e territori, abbandoni e ritorni
2020
Il contributo riflette sulle identità dei territori, e su come queste siano in grado di orientare certe dinamiche all’interno delle comunità, sul fenomeno dello spopolamento e degli abbandoni – problema che negli ultimi tempi, soprattutto nel Meridione italiano, è al centro del dibattito politico e scientifico – e sul caso specifico di Mamoiada, comune della Sardegna interna che, sino agli anni Novanta del secolo scorso, ha scontato un importante decremento della popolazione e una forte disgregazione sociale dovuti in massima parte ai fatti criminali che si sono succeduti per più di trent’anni e oggi, come la quasi totalità dei comuni delle aree interne, si confronta con la denatalità, l’in…
CAMPANARO v FIP (ATTO II°): ILLEGITTIMA APPLICAZIONE ART. 11 BIS
2014
Sport; Applicazione art. 11 bis del Regolamento esecutivo-settore professionistico FIP; Il Consiglio di Stato ritiene illegittima l’applicazione di tale previsione
Los efectos directos y colaterales de la disolución de Herri Batasuna
2005
Alexandre.Catala@uv.es La ilegalización de Herri Batasuna, Euskal Herritarrok y Batasuna (Sentencia del Tribunal Supremo de 27 de marzo de 2003) comportó una serie de consecuencias que son analizadas en el presente trabajo. En primer lugar, la estrategia de presentar en sucesivos comicios (elecciones municipales y autonómicas de 2003, elecciones al Parlamento Europeo de 2004 y elecciones al Parlamento vasco de 2005) agrupaciones electorales que no eran más que continuación de aquéllos con la clara intención de burlar la aplicación de la Ley Orgánica de Partidos Políticos y perpetuar así su actividad. En segundo lugar, la polémica sobre la disolución del grupo parlamentario correspondiente e…
Prophylactic and therapeutic intervention in IgE responses by biolistic DNA vaccination primarily targeting dendritic cells.
2005
Background Allergen gene transfer represents an alternative approach to specific immunotherapy with allergen extracts. Gene gun–mediated DNA immunization with plasmid vectors expressing a transgene under control of the promoter of the fascin gene (pFascin) allows for antigen production predominantly by dendritic cells and resulted in the generation of CD8 + cytotoxic T lymphocytes as well as in the development of a type 1 immune response. Objective We compared the in vivo efficiency of biolistic transfection with pFascin and plasmids containing the cytomegalovirus promoter (pCMV) in a mouse model of type I allergy. Methods BALB/c mice were sensitized with the model allergen β-galactosidase …
Valorization of rapeseed meal by solid state fermentation for an application in animal nutrition
2017
Solid state fermentation (SSF) is a biotechnological process particularly well adapted to the treatment of vegetable biomass. This technology adjustable to industrial scale, is adapted to current challenges in animal nutrition by developing fermented products in order to improve the quality of raw materials from a nutritional and functional point of view. The work presented in this thesis considers these issues using rapeseed meal from the oil crushing industry.A first screening study highlighted several fungal strains based on their growth performance and protein enrichment (total and digestible) of the substrate. Levels similar to those of soybean meal, the main protein source in animal n…
Molecular basis of filamin a-filGAP interaction and its impairment in congenital disorders associated with filamin a mutations
2008
Background Mutations in filamin A (FLNa), an essential cytoskeletal protein with multiple binding partners, cause developmental anomalies in humans. Methodology/Principal Findings We determined the structure of the 23rd Ig repeat of FLNa (IgFLNa23) that interacts with FilGAP, a Rac-specific GTPase-activating protein and regulator of cell polarity and movement, and the effect of the three disease-related mutations on this interaction. A combination of NMR structural analysis and in silico modeling revealed the structural interface details between the C and D β-strands of the IgFLNa23 and the C-terminal 32 residues of FilGAP. Mutagenesis of the predicted key interface residues confirmed the b…
Congenital myopathies with inclusion bodies: a brief review
1998
Abstract Based on morphological abnormalities, congenital myopathies can be classified into several categories: (1) enzyme histochemically abnormal appearance without structural pathology, e.g. congenital fibre type disproportion or congenital fibre type uniformity; (2) abnormally placed nuclei, e.g. myotubular and centronuclear myopathies; (3) disruption of normal intrinsic structures, largely sarcomeres, e.g. central cores and minicores; (4) abnormal inclusions within muscle fibres. Several such inclusions are derived from pre-existing structures, most notably rods or nemaline bodies. Other derivatives of Z-band material are cytoplasmic bodies and possibly related inclusions as spheroid b…
El último intelectual
2007
Neuroproteomics in the auditory brainstem: candidate proteins for ultrafast and precise information processing.
2014
In the mammalian auditory brainstem, the cochlear nuclear complex (CN) and the superior olivary complex (SOC) feature structural and functional specializations for ultrafast (<1 ms) and precise information processing. Their proteome, the basis for structure and function, has been rarely analyzed so far. Here we identified and quantified the protein profiles of three major auditory brainstem regions of adult rats, the CN, the SOC, and the inferior colliculus (IC). The rest of the brain served as a reference. Via label-free quantitative mass spectrometry and 2-D DIGE/MALDI-MS, we identified 584 and 297 proteins in the plasma membrane/synaptic vesicle proteome and the cytosolic proteome, respe…
L’INSINDACABILITÀ FRA EQUILIBRIO DEI POTERI ED UGUAGLIANZA DEI DIRITTI
2010
RESUMEN El Estado italiano ha sido condenado por el Tribunal Europeo de Derechos Humanos por la violación del artículo 6.1 del Convenio, en todos aquellos casos relativos a la prerogativa de la inviolabilidad (insindacabilità) parlamentaria prevista en el artículo 68.1 de la Constitución. Atendiendo al dato apuntado, puede afirmarse que la necesaria garantía del principio de separación de poderes, en tanto que elemento esencial de la “arquitectura constitucional” viene a colisionar con la protección de los derechos fundamentales, al desconocer las exigencias derivadas del principio de proporcionalidad. El caso de la inviolabilidad italiana parece desviarse, por lo que a su aplicación se ref…