Search results for "Lamina"

showing 10 items of 439 documents

Electron microscopic localization of nitric oxide I synthase in the organ of Corti of the guinea pig

1997

Nitric oxide synthase (NOS) activity has been detected previously in the mammalian cochlea at a light microscopic level. Here we present results of electron microscopic analysis for post-embedding immunoreactivity of neural-type NOS I in the cochlea of the guinea pig. Strong enzyme immunoreactivity was identified in the cytoplasm of inner and outer hair cells. Gold-labeled NOS I antibodies were mainly located in electron-dense areas of the cytoplasm, whereas electron-lucent regions of the receptor cells were nearly free from any immunoreactivity. In both types of hair cells anti-NOS I antibodies were also visible in the cuticular plates, hair bundles and nuclei. Further ultrastructural anal…

Cell typeGuinea PigsBiologyPitch DiscriminationReference ValuesHair Cells AuditorymedicineAnimalsInner earOrgan of CortiCochleaLamina reticularisGeneral MedicineImmunohistochemistryCell biologyIsoenzymesMicroscopy Electronmedicine.anatomical_structureOtorhinolaryngologyBiochemistryCytoplasmOrgan of CortiUltrastructuresense organsHair cellNitric Oxide SynthaseSignal TransductionEuropean Archives of Oto-Rhino-Laryngology
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Morphology of follicle cells of Libellulidae (Odonata)

2011

In libellulids, mature oocyte size varies within and between individual ovaries. The regulating mechanism is not yet understood. Variations in the contents of the follicle cells, and thereby their ability to secrete material into the oocyte, might explain some of the observed differences in oocyte size. We therefore investigated the follicle cell surface, the interstitial space width between follicle cells and between follicle cells and oocytes, the number of nuclei, and the cell compartment proportions using scanning and transmission electron microscopy. In all investigated species, the follicle cells were covered by a basal lamina. We found cytoplasmic microvilli and septate junctions. As…

CellSeptate junctionsAnatomyBiologyOocyteEndocytosisCell biologyFolliclemedicine.anatomical_structureInterstitial spaceCytoplasmInsect SciencemedicineBasal laminaEcology Evolution Behavior and SystematicsInternational Journal of Odonatology
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Stability of melt flow due to a traveling magnetic field in a closed ampoule

2004

The linear three-dimensional instability of the flow due to a low frequency traveling magnetic field in a regular cylinder is studied numerically for height-to-diameter ratios in the range [0.5:2.5]. The first instability has the form of an azimuthal wave with wave numbers between 1 and 6 depending on the aspect ratio. It is shown that the flow is stable if the Reynolds number is below 290. Even stronger stationary flows may be obtained in a flattened cylinder.

ChemistryReynolds numberLaminar flowMechanicsCondensed Matter PhysicsInstabilityMagnetic fieldPhysics::Fluid DynamicsInorganic Chemistrysymbols.namesakeClassical mechanicsHele-Shaw flowFlow (mathematics)Materials ChemistrysymbolsWavenumberCylinderJournal of Crystal Growth
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The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression

2008

Inner nuclear membrane proteins containing a LEM (LAP2, emerin, and MAN1) domain participate in different processes, including chromatin organization, gene expression, and nuclear envelope biogenesis. In this study, we identify a robust genetic interaction between transcription export (TREX) factors and yeast Src1, an integral inner nuclear membrane protein that is homologous to vertebrate LEM2. DNA macroarray analysis revealed that the expression of the phosphate-regulated genes PHO11, PHO12, and PHO84 is up-regulated in src1Δ cells. Notably, these PHO genes are located in subtelomeric regions of chromatin and exhibit a perinuclear location in vivo. Src1 spans the nuclear membrane twice an…

Chromatin ImmunoprecipitationSaccharomyces cerevisiae ProteinsGenes FungalSaccharomyces cerevisiaeProtein Sorting SignalsBiologyArticleGenètica molecularProton-Phosphate SymportersGene Expression Regulation FungalGene expressionmedicineExpressió genèticaInner membraneNuclear proteinNuclear poreNuclear membraneResearch ArticlesNucleoplasmMembrane ProteinsNuclear ProteinsCell BiologyTelomereMolecular biologyChromatinProtein Structure TertiaryChromatinAlternative SplicingGenòmicamedicine.anatomical_structureMultiprotein ComplexesNuclear lamina
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Phenoloxidase characterization in vacuolar hemocytes from the solitary ascidian Styela plicata

1995

Phenoloxidase (PO) activity was shown in lysates of Styela plicata hemocytes assayed spectrophotometrically by means of L-Dopa oxidation without divalent cations. Trypsin and chymotrypsin pretreatment and preincubation with microbial lipopolysaccharides significantly activated PO, whereas laminarin or zymosan were ineffective. Soybean trypsin inhibitor, tropolone, and phenylthiourea, but not benzamidine, were inhibitors. Finally, hemocytes were separated by a discontinuous Percoll density gradient to determine which cells were active. PO activity was demonstrated, by both biochemical and cytochemical assays, in the separated fraction enriched mainly with the globular granulocytes called mor…

ChymotrypsinbiologyKunitz STI protease inhibitorL-DopaHemocytebiology.organism_classificationTrypsinMorula cellTunicateBenzamidineLaminarinchemistry.chemical_compoundStyela plicatachemistryBiochemistryHemolymphbiology.proteinmedicinePhenoloxidasePercollEcology Evolution Behavior and Systematicsmedicine.drug
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The durability of basalt fibres reinforced polymer (BFRP) panels for cladding

2015

The study focuses on two basalt composite laminate panels for cladding, produced by means of vacuum bagging technique. In particular, unidirectional and random basalt fabrics, with different areal weights, using epoxy resin as matrix, were used. According to the ISO 15686 methodology for the evaluation of durability, samples were subjected to cycles of artificial aging in climatic chamber and outdoor exposure, carrying out mechanical (i.e. quasi-static and dynamic) and calorimetric tests. The results show the effectiveness over time of produced basalt composite laminates and the initial increase of the mechanical performances after the first steps of accelerated aging.

Cladding (metalworking)Materials scienceComposite numberMechanical performanceSettore ICAR/11 - Produzione Edilizia02 engineering and technology010402 general chemistry01 natural sciencesLaminated composite panelDurabilityGeneral Materials ScienceComposite materialCivil and Structural Engineeringchemistry.chemical_classificationBuilding and ConstructionEpoxyPolymerComposite laminates021001 nanoscience & nanotechnologyDurabilityAccelerated aging0104 chemical sciencesSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialichemistryMechanics of Materialsvisual_artSolid mechanicsvisual_art.visual_art_medium0210 nano-technologyBasalt fibre
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Riming of Graupel: Wind Tunnel Investigations of Collection Kernels and Growth Regimes

2009

Abstract Laboratory experiments were carried out in the vertical wind tunnel in Mainz, Germany, to study the collision coalescence growth of single spherical ice particles having initial radii between 290 and 380 μm while they were freely floated in a laminar flow containing a cloud of supercooled droplets with radii between 10 and 20 μm. The experiments were performed in a temperature range between −8 and −12°C, where riming proceeds in the atmosphere, and with cloud liquid water contents lying between 0.9 and 1.6 g m−3 (i.e., values typically found in mixed-phase clouds). The collection kernels were calculated from the mass increase of the rimed ice particles and the average liquid water …

Coalescence (physics)Atmospheric ScienceMaterials scienceMeteorologyLiquid water contentLaminar flowAstrophysics::Earth and Planetary AstrophysicsMechanicsSupercoolingTemperature measurementGraupelWind tunnelIcingJournal of the Atmospheric Sciences
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Evolution Characteristics of Delamination Damage in CFRP Composites Under Transverse Loading

2012

The initiation and subsequent progression of delamination in CFRP composite laminates is examined using finite element method. A 12-ply CFRP composite, with a total thickness of 2.4 mm and anti-symmetric ply sequence is simulated under three-point bend test setup. Each unidirectional composite lamina is treated as an equivalent elastic and orthotropic panel. Interface behavior is defined using cohesive damage model. Complementary three-point bend test on the specimen is performed at crosshead speed of 2 mm/min. The measured load–deflection response at mid-span location compares well with predicted values. Interface delamination accounts for up to 46.7% reduction in flexural stiffness from t…

Cohesive zone modelMaterials scienceFlexural strengthComposite numberUltimate tensile strengthDelaminationFlexural rigidityComposite laminatesComposite materialOrthotropic material
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Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure

1999

BACKGROUND/AIMSReplication deficient recombinant adenoviruses represent an efficient means of transferring genes in vivo into a wide variety of dividing and quiescent cells from many different organs. Although the gastrointestinal tract is a potentially attractive target for gene therapy approaches, only a few studies on the use of viral gene transfer vehicles in the gut have been reported. The prospects of using recombinant adenoviruses for gene delivery into epithelial and subepithelial cells of the normal and inflamed colon are here analysed.METHODSAn E1/E3 deleted recombinant adenovirus (denoted AdCMVβGal) and an adenovirus with modified fibre structure (denoted AdZ.F(pk7)) both express…

ColonT cellGenetic enhancementGenetic VectorsGene ExpressionBiologyGene deliverymedicine.disease_causeRecombinant virusArticleAdenoviridaeMiceAdministration RectalGene expressionmedicineAnimalsHumansReporter geneLamina propriaMice Inbred BALB CGastroenterologyGene Transfer TechniquesDefective VirusesColitisInflammatory Bowel Diseasesbeta-GalactosidaseVirologyMolecular biologyAdenoviridaemedicine.anatomical_structureInjections IntravenousInjections Intraperitoneal
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Numerical and Experimental Analysis of the Frictional Effects on 4ENF Delamination Tests Performed on Unidirectional CFRP

2015

Abstract Progressive delamination in composite materials under static or fatigue loading condition are, in many structures, one of the predominant cause of failure. In the paper, an accurate study of quasi-static delamination growth under mode II loading condition is conducted. Several experimental tests are performed on composite laminates consisting of unidirectional carbon/epoxy layers. Four-point end-notched flexure (4ENF) test is employed in order to characterize the mode II interlaminar fracture toughness. The R-curve is obtained by means of optical and numerical determination of crack tip position. The energy release rate and the crack length are calculated through experimental deter…

Composite materialMaterials scienceSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineFracture toughnessEngineering (all)Composite materialCFRPSettore ING-IND/15 - Disegno E Metodi Dell'Ingegneria IndustrialeEngineering(all)Cohesive Zone ModelMode IIStrain energy release rateFiber pull-outbusiness.industryDelaminationGeneral MedicineStructural engineeringComposite materialsDissipationComposite laminatesCompression (physics)Cohesive zone modelDelamination4ENF.4ENFbusinessSettore ICAR/08 - Scienza Delle CostruzioniProcedia Engineering
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