Search results for "Large"

showing 10 items of 2197 documents

Patterns of oncogene co-expression at single cell resolution in cancer influence survival

2020

AbstractBackgroundCancers often overexpress multiple clinically relevant oncogenes. However, it is not known if multiple oncogenes within a cancer combine uniquely in specific cellular sub-populations to influence clinical outcome. We studied this phenomenon using the prognostically relevant oncogenes MYC, BCL2 and BCL6 in Diffuse Large B-Cell Lymphoma (DLBCL).MethodsQuantitative multispectral imaging simultaneously measured oncogene co-expression at single-cell resolution in reactive lymphoid tissue (n=12) and four independent cohorts (n=409) of DLBCL. Mathematically derived co-expression phenotypes were evaluated in DLBCLs with immunohistochemistry (n=316) and eight DLBCL cohorts with gen…

Quantitative immunohistochemistryCellBiologyBCL6medicine.diseasemedicine.anatomical_structureimmune system diseaseshemic and lymphatic diseasesGene expressionCo localisationmedicineCancer researchImmunohistochemistryneoplasmsDiffuse large B-cell lymphomaPatient stratification
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Supersymmetry parameter analysis: SPA convention and project.

2005

18 páginas, 6 figuras, 12 tablas.-- et al.

Quantum Field TheoryScheme (programming language)Particle physicsCold dark matterExperimental PhysicsPhysics and Astronomy (miscellaneous)FOS: Physical sciences01 natural scienceslaw.inventionSet (abstract data type)High Energy Physics - Phenomenology (hep-ph)law0103 physical sciencesddc:530010306 general physicsColliderEngineering (miscellaneous)Particle Physics - PhenomenologyNuclear Physicscomputer.programming_languagePhysicsLarge Hadron Collider010308 nuclear & particles physicsFísicaObservableSupersymmetryPhysics beyond the Standard ModelHigh Energy Physics - Phenomenology[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]Production (computer science)computerElementary Particles
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Production of inclusive ϒ(1S) and ϒ(2S) in p–Pb collisions at sNN=5.02 TeV

2015

We report on the production of inclusive Y{hooktop}(1S) and Y{hooktop}(2S) in p-Pb collisions at √sNN=5.02 TeV at the LHC. The measurement is performed with the ALICE detector at backward (-4.46<ycms<-2.96) and forward (2.03<ycms<3.53) rapidity down to zero transverse momentum. The production cross sections of the Y{hooktop}(1S) and Y{hooktop}(2S) are presented, as well as the nuclear modification factor and the ratio of the forward to backward yields of Y{hooktop}(1S). A suppression of the inclusive Y{hooktop}(1S) yield in p-Pb collisions with respect to the yield from pp collisions scaled by the number of binary nucleon-nucleon collisions is observed at forward rapidity but not at backwar…

Quantum chromodynamicsNuclear physicsPhysicsNuclear and High Energy PhysicsLarge Hadron ColliderYield (chemistry)Transverse momentumBinary numberProduction (computer science)RapidityNuclear Experiment7. Clean energyColor-glass condensatePhysics Letters B
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Elliptic flow in nuclear collisions at ultrarelativistic energies available at the CERN Large Hadron Collider

2009

We use perfect-fluid hydrodynamical model to predict the elliptic flow coefficients in $\mathrm{Pb}+\mathrm{Pb}$ collisions at the Large Hadron Collider (LHC). The initial state for the hydrodynamical calculation for central $A+A$ collisions is obtained from the perturbative QCD $+$ saturation model. The centrality dependence of the initial state is modeled by the optical Glauber model. We show that the baseline results obtained from the framework are in good agreement with the data from the Relativistic Heavy Ion Collider and show predictions for the ${p}_{T}$ spectra and elliptic flow of pions in $\mathrm{Pb}+\mathrm{Pb}$ collisions at the LHC. Also mass and multiplicity effects are discu…

Quantum chromodynamicsNuclear physicsPhysicsNuclear and High Energy PhysicsParticle physicsPionLarge Hadron ColliderElliptic flowPerturbative QCDNuclear ExperimentRelativistic Heavy Ion ColliderGlauberSpectral linePhysical Review C
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Measuring KS0K± interactions using Pb–Pb collisions at sNN=2.76 TeV

2019

We present the first measurements of femtoscopic correlations between the KS0 and K± particles in pp collisions at s=7 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding solely via the a0(980) resonance. The extracted kaon source radius and correlation strength parameters for KS0K− are found to be equal within the experimental uncertainties to those for KS0K+ . Results of the present study are compared with those from identical-kaon femtoscopic studies also performed with pp collisions at s=7 TeV by ALICE and with a KS0K± measurement in Pb–Pb collisions at sNN=2.76 TeV. Combined with the Pb–Pb results, our pp a…

Quantum chromodynamicsPhysicsCouplingNuclear and High Energy PhysicsLarge Hadron Collider010308 nuclear & particles physicsRadius01 natural sciencesResonance (particle physics)Particle identificationNuclear physicsDiquarkHadron physics0103 physical sciencesStatistical analysisTetraquark010306 general physicsPhysics Letters B
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W+W−Production at Hadron Colliders in Next to Next to Leading Order QCD

2014

Charged gauge boson pair production at the Large Hadron Collider allows detailed probes of the fundamental structure of electroweak interactions. We present precise theoretical predictions for on-shell W+ W- production that include, for the first time, QCD effects up to next to next to leading order in perturbation theory. As compared to next to leading order, the inclusive W+ W- cross section is enhanced by 9% at 7 TeV and 12% at 14 TeV. The residual perturbative uncertainty is at the 3% level. The severe contamination of the W+ W- cross section due to top-quark resonances is discussed in detail. Comparing different definitions of top-free W+ W- production in the four and five flavor numbe…

Quantum chromodynamicsPhysicsGauge bosonParticle physicsLarge Hadron Collider010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyHadronElectroweak interactionGeneral Physics and Astronomy7. Clean energy01 natural sciencesCross section (physics)Pair production0103 physical sciencesHigh Energy Physics::ExperimentPerturbation theory (quantum mechanics)010306 general physicsPhysical Review Letters
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Large Effects from Small QCD Instantons: Making Soft Bombs at Hadron Colliders

2020

It is a common belief that the last missing piece of the Standard Model of particles physics was found with the discovery of the Higgs boson at the Large Hadron Collider. However, there remains a major prediction of quantum tunnelling processes mediated by instanton solutions in the Yang-Mills theory, that is still untested in the Standard Model. The direct experimental observation of instanton-induced processes, which are a consequence of the non-trivial vacuum structure of the Standard Model and of quantum tunnelling in QFT, would be a major breakthrough in modern particle physics. In this paper, we present for the first time a full calculation of QCD instanton-induced processes in proton…

Quantum chromodynamicsPhysicsHigh Energy Physics - TheoryNuclear and High Energy PhysicsParticle physicsInstantonLarge Hadron Collider010308 nuclear & particles physicsHigh Energy Physics::LatticeHadronHigh Energy Physics::PhenomenologyFOS: Physical sciencesQCD Phenomenology01 natural sciencesStandard ModelGluonHigh Energy Physics - PhenomenologyHigh Energy Physics - Phenomenology (hep-ph)High Energy Physics - Theory (hep-th)0103 physical sciencesHiggs bosonlcsh:QC770-798lcsh:Nuclear and particle physics. Atomic energy. Radioactivity010306 general physicsEvent generator
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Results from pQCD for A+A collisions at RHIC &amp; LHC energies

2000

This talk will discuss how to compute initial quantites in heavy ion collisions at RHIC (200 AGeV) and at LHC (5500 AGeV) using perturbative QCD (pQCD) by including the next-to-leading order (NLO) corrections and a dynamical determination of the dominant physical scale. The initial numbers are converted into final ones by assuming kinetic thermalization and adiabatic expansion.

Quantum chromodynamicsPhysicsLarge Hadron ColliderHigh Energy Physics::PhenomenologyPerturbative QCDFOS: Physical sciencesKinetic energyNuclear physicsHigh Energy Physics - PhenomenologyThermalisationHigh Energy Physics - Phenomenology (hep-ph)Heavy ionHigh Energy Physics::ExperimentPerturbation theory (quantum mechanics)Adiabatic processNuclear Experiment
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Measurement of ϒ(1S) Elliptic Flow at Forward Rapidity in Pb-Pb Collisions at sNN=5.02  TeV

2019

The first measurement of the Υ(1S) elliptic flow coefficient (v2) is performed at forward rapidity (2.5 < y < 4) in Pb–Pb collisions at √sNN=5.02 TeV with the ALICE detector at the LHC. The results are obtained with the scalar product method and are reported as a function of transverse momentum (pT) up to 15 GeV/c in the 5%–60% centrality interval. The measured Υ(1S)v2 is consistent with 0 and with the small positive values predicted by transport models within uncertainties. The v2 coefficient in 2 < pT < 15 GeV/c is lower than that of inclusive J/ψ mesons in the same pT interval by 2.6 standard deviations. These results, combined with earlier suppression measurements, are in agreement with…

Quantum chromodynamicsPhysicsLarge Hadron ColliderMesonElliptic flowGeneral Physics and AstronomyQuarkonium01 natural sciencesStandard deviationNuclear physics0103 physical sciencesQuark–gluon plasmaRapidityNuclear Experiment010306 general physicsPhysical Review Letters
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Small-x physics at the LHeC

2018

The Large Hadron-electron Collider LHeC is a proposed upgrade of the LHC. It would add an electron beam to the LHC, and make it possible to study electron-proton and electron-nucleus collisions at very high energies. We present some of the highlights of the LHeC physics program related to the studies of partonic structure of protons and nuclei, and to the non-linear QCD phenomena visible at small $x$.

Quantum chromodynamicsPhysicsLarge Hadron ColliderNuclear TheoryNuclear TheoryHigh Energy Physics::PhenomenologyFOS: Physical scienceshiukkasfysiikkalaw.inventionNuclear physicsNuclear Theory (nucl-th)High Energy Physics - PhenomenologyUpgradeHigh Energy Physics - Phenomenology (hep-ph)lawPhysics::Accelerator PhysicsHigh Energy Physics::ExperimentNuclear Experiment (nucl-ex)ColliderNuclear ExperimentydinfysiikkaNuclear theoryNuclear Experiment
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