Search results for "Latent variable"

Imputation of posterior linkage probability relations reveals a significant influence of structural 3D constraints on linkage disequilibrium

2018

Genetic association studies have become increasingly important in unraveling the genetics of diseases or complex traits. Despite their value for modern genetics, conflicting conclusions often arise through the difficulty of confirming and replicating experimental results. We argue that this problem is largely based on the application of statistical relation measures that are not appropriate for genomic data analysis and demonstrate that the standard measures used for Genome-wide association studies or genomics linkage analysis bear a statistic bias. This may come from the violation of underlying assumptions (such as independence or stationarity) as well as from other conceptual limitations …

Improved Predictability for Foreign Direct Investors by Comprising Different Macroeconomic Levels: A New Model Approach

2020

Foreign direct investments have grown over the last decades which are related to the ongoing globalization process. The current literature shows research works dealing with the topic of influence factors on foreign direct investment (FDI) decisions which may occur during the decision-making process. A new causal model has been developed to get in-depth view on macroeconomic perspective. Motives to do FDI are strongly impacted by macroeconomic factors which may influence upcoming decisions. To be able to understand the impact of the macroeconomic environment on FDI decisions the factors have been diversified and conceptualized, divided into three subgroups of independent latent variables in …

Resilience and coping as predictors of general well-being in the elderly: A structural equation modeling approach

2012

The aims of this article are: (a) to test for the validity of the three constructs involved in the structural model; (b) to test for the effects of both coping strategies and resilient coping on well-being in a sample of elderly, by means of a structural model with latent variables; (c) to empirically study whether a brief scale of resilient coping could predict well-being over and above that predicted by the coping resources.The research is a survey design. The sample consisted of 225 non-institutionalized elderly people living in the city of Valencia (Spain). The three constructs measured were: well-being, resilient coping, and coping strategies.The analyses consist of a series of alterna…

Screening for depressive symptoms in adolescents at school: New validity evidences on the short form of the Reynolds Depression Scale.

2017

The main purpose of the present study was to assess the depressive symptomatology and to gather new validity evidences of the Reynolds Depression Scale-Short form (RADS-SF) in a representative sample of youths. The sample consisted of 2914 adolescents with a mean age of 15.85 years (SD = 1.68). We calculated the descriptive statistics and internal consistency of the RADS-SF scores. Also, confirmatory factor analyses (CFAs) at the item level and successive multigroup CFAs to test measurement invariance, were conducted. Latent mean differences across gender and educational level groups were estimated, and finally, we studied the sources of validity evidences with other external variables. The…

A framework for identifying the adaptations responsible for differences in pegboard times between middle-aged and older adults

2017

Time to complete two tests of manual dexterity, the 9-hole Peg Test and Grooved Pegboard Test, increases with advancing age. However, the adaptations responsible for the differences in pegboard times betweenmiddle-aged and older adults are largely unknown. Potential mechanisms include neuromuscular characteristics, cognitive function, and cutaneous sensation. To provide a tractable framework to address these gaps in knowledge, the purpose of the current study was to identify the latent variables underlying age-associated differences in time to complete the 9-hole and grooved pegboard tests. The approach involved an independent component analysis that identified associations between the two …

Religiosity and cultural consumption

2018

Development of Customer-Orientation, Brand-Orientation and Business Performance within the First Ten Years of the Firm

2017

The business performance of young firms is significantly influenced by customer- and brand-oriented capabilities. These capabilities can be sustained competitive advantages for firms from an early age on and managers need to consciously develop them over time. In the first years, the development of these firms is still highly dependent on their environment. The products and services are still under development, and there are only little resources and market information available. Therefore, the development of customer-orientation, brand-orientation and their impact on business performance at this age is crucial to be understood for founders to appropriately manage these capabilities. The pu…

Structural invariants for the prediction of relative toxicities of polychloro dibenzo-p-dioxins and dibenzofurans

2004

Multivariate models are reported that can predict the relative toxicity of compounds with severe environmental impact, namely polychloro dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Multiple linear regression analysis (MLR) and partial least square projections of latent variables (PLS) show the usefulness of graph-theoretical descriptors, mainly topological charge indices (TCIs), in these series. The general trends of the group are correctly reproduced and better results are presented than have previously been published. In general, the more toxic compounds exhibit more symmetric molecular structures.

Psychological models of development of idiopathic environmental intolerances: Evidence from longitudinal population-based data.

2021

Abstract The origin of idiopathic environmental intolerances (IEIs) is an open question. According to the psychological approaches, various top-down factors play a dominant role in the development of IEIs. The general psychopathology model assumes a propensity towards mental ill-health (negative affectivity) increases the probability of developing IEIs. The attribution model emphasizes the importance of mistaken attribution of experienced somatic symptoms; thus, more symptoms should lead to more IEIs. Finally, the nocebo model highlights the role of expectations in the development of IEIs. In this case, worries about the harmful effects of environmental factors are assumed to evoke IEIs. We…

The effects of organizational and individual factors on occupational accidents

2002

This study examined the relationships between individual psychological, work environment and organizational variables and occupational accidents using structural equation modelling with latent variables. A series of nested explicative models of the relationships between these variables was derived. Data were collected from a wide range of industrial sectors in the Valencia region of Spain using structured interviews. In total, 525 valid questionnaires were completed and these formed the basis for the subsequent analyses. Analysis showed that the model in the series that proposed relationships between all the latent variables provided the best representation of the data. This supported the b…