Search results for "Lates"

showing 10 items of 738 documents

Dietary cholate increases plasma levels of apolipoprotein B in mice by posttranscriptional mechanisms

2001

To induce atherogenesis in mice, a high fat (HF) diet is supplemented with cholic acid (CA), which increases apoB-containing particles and lower apoA-I-containing particles. HF diet without CA increases levels of both HDL and LDL, suggesting that CA may be responsible for the elevation of LDL and lowering of HDL. The mechanism of dietary CA-induced lowering of apoA-I-containing particles has recently been reported. In this study, we examined the mechanism of CA- and HF-induced elevation of apoB-containing lipoproteins in mice. Mice were fed the following four diets: control chow (C), high fat high cholesterol, (HF), control and 0.5% cholate (CA), and HF + CA. Dietary CA increased the plasma…

medicine.medical_specialtyVery low-density lipoproteinSettore MED/09 - Medicina InternaMouseApolipoprotein Bmedicine.medical_treatmentDown-RegulationCholic AcidLipoproteins VLDLBiochemistryDietary cholateMicechemistry.chemical_compoundApolipoproteins ERibonucleasesDownregulation and upregulationInternal medicinemedicineAnimalsVitamin ERNA MessengerRNA Processing Post-TranscriptionalReceptorApolipoproteins BbiologyChemistryVitamin ECholic acidnutritional and metabolic diseasesCell BiologyBlotting NorthernDietLipoproteins LDLMice Inbred C57BLCholesterolEndocrinologyLiverReceptors LDLLDL receptorbiology.proteinlipids (amino acids peptides and proteins)Gene expressionHepatic lipaseApolipoprotein BCholatesDietary fatThe International Journal of Biochemistry & Cell Biology
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The European multicenter cohort study on cyanoacrylate embolization of refluxing great saphenous veins

2014

ObjectiveCyanoacrylate (CA) embolization of refluxing great saphenous veins (GSVs) has been previously described. The outcomes from a multicenter study are still lacking.MethodsA prospective multicenter study was conducted in seven centers in four European countries to abolish GSV reflux by endovenous CA embolization. Neither tumescent anesthesia nor postinterventional compression stockings were used. Varicose tributaries remained untreated until at least 3 months after the index treatment. Clinical examination, quality of life assessment, and duplex ultrasound evaluation were performed at 2 days and after 1, 3, 6, and 12 months.ResultsIn 70 patients, of whom 68 (97.1%) were available for 1…

medicine.medical_specialtymedicine.medical_treatmentPhysical examinationCompression stockingslaw.inventionCohort StudieslawVaricose veinsHumansMedicineSaphenous VeinCyanoacrylatesProspective StudiesEmbolizationProspective cohort studyTumescent anesthesiamedicine.diagnostic_testbusiness.industryRefluxEmbolization TherapeuticSurgeryEuropeTreatment OutcomeVenous InsufficiencyCyanoacrylateAnesthesiaQuality of LifeSurgerymedicine.symptomCardiology and Cardiovascular MedicinebusinessJournal of Vascular Surgery: Venous and Lymphatic Disorders
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Transcatheter embolization of the kidney with butyl-2-cyanoacrylate: Experimental and clinical results

1978

The technique and efficacy of therapeutic catheter embolization of the kidney with butyl-2-cyanoacrylate (Histoacryl) were studied in 80 rabbits (including control groups) and in 10 dogs. A mixture of butyl-2-cyanoacrylate, 50% glucose, and tantalum powder was used for the embolization. Complete and permanent vascular occlusion was found in nearly all cases. The main complication observed was a reflux of embolizing material into the lumbar arteries, which occurred in seven rabbits. Clinically, therapeutic embolization was performed in six patients with hypernephroma. The indication for embolization in these patients, as well as in two others with iatrogenic lesions, was pronounced hematuria…

medicine.medical_specialtymedicine.medical_treatmentTantalumAdenocarcinomaVascular occlusionCatheterizationlaw.inventionDogsRenal Arterylawmedicine.arterymedicineAnimalsHumansRadiology Nuclear Medicine and imagingCyanoacrylatesEmbolizationHematuriaKidneybusiness.industryLumbosacral RegionRefluxEnbucrilateEmbolization TherapeuticKidney NeoplasmsSurgeryRadiographyCathetermedicine.anatomical_structureCyanoacrylateRabbitsRadiologymedicine.symptomCardiology and Cardiovascular MedicineComplicationbusinessLumbar arteriesCardiovascular Radiology
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Motor imagery and cortico-spinal excitability: A review

2016

International audience; Motor imagery (MI) has received a lot of interest during the last decades as its chronic or acute use has demonstrated several effects on improving sport performances or skills. The development of neuroimagery techniques also helped further our understanding of the neural correlates underlying MI. While some authors showed that MI, motor execution and action observation activated similar motor cortical regions, transcranial magnetic stimulation (TMS) studies brought great insights on the role of the primary motor cortex and on the activation of the cortico-spinal pathway during MI. After defining MI and describing the TMS technique, a short report of MI activities on…

medicine.medical_treatmentPhysical Therapy Sports Therapy and RehabilitationAthletic Performance050105 experimental psychologyneuroscience03 medical and health sciences0302 clinical medicineMotor imagery[ INFO.INFO-BI ] Computer Science [cs]/Bioinformatics [q-bio.QM]medicinemotor controlHumans0501 psychology and cognitive sciencesOrthopedics and Sports MedicineNeural correlates of consciousnessmusculoskeletal neural and ocular physiology05 social sciencesMotor CortexMotor controlElectroencephalographyGeneral MedicineMagnetic Resonance ImagingTranscranial magnetic stimulationSpinal Cordnervous system[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Action observationImaginationPrimary motor cortexPsychologyNeurosciencePsychomotor Performance030217 neurology & neurosurgeryMotor executionTranscranial magnetic stimulationperformanceMuscle Contraction
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Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres

2015

Abstract Although cancer stem-like cells (CSCs) are rare, they can enter a non-proliferative or dormant state and resist therapy. Furthermore, quiescent CSCs are responsible for metastases that can appear after curative surgical treatment of a primary tumor. Because of drug resistance of CSCs, the development of novel therapies is urgently required that specifically target CSCs. Purpose The aim of the present study was to investigate the potential of a panel of natural products and derivatives to inhibit CSC-enriched mammospheres of MCF-7 breast cancer cells. Methods CD44high/CD24low cells were identified by flow cytometry and maintained as mammospheres. As a control, we used two clinically…

medicine.medical_treatmentPhytochemicalsCellArtesunatePharmaceutical ScienceAntineoplastic AgentsBiologyPharmacologyFlow cytometrySpheroids CellularStilbenesDrug DiscoverymedicineHumansCytotoxicityPharmacologyChemotherapymedicine.diagnostic_testCancermedicine.diseasePrimary tumorArtemisininsSalicylatesmedicine.anatomical_structureComplementary and alternative medicineDocetaxelMCF-7MCF-7 CellsNeoplastic Stem CellsMolecular MedicineNaphthoquinonesmedicine.drugPhytomedicine
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Stability of radial head and neck fractures: a biomechanical study of six fixation constructs with consideration of three locking plates.

2007

Open reduction and internal fixation of radial neck fractures can lead to secondary loss of reduction and nonunion due to insufficient stability. Nevertheless, there are only a few biomechanical studies about the stability achieved by different osteosynthesis constructs.Forty-eight formalin-fixed, human proximal radii were divided into 6 groups according to their bone density (measured by dual-energy x-ray absorptiometry). A 2.7-mm gap osteotomy was performed to simulate an unstable radial neck fracture, which was fixed with 3 nonlocking implants: a 2.4-mm T plate, a 2.4-mm blade plate, and 2.0-mm crossed screws, and 3 locking plates: a 2.0-mm LCP T plate, a 2.0-mm 6x2 grid plate, and a 2.0…

medicine.medical_treatmentTorsion MechanicalOsteotomyProsthesis DesignFracture Fixation InternalCadaverFracture fixationBone plateMaterials TestingmedicineCadaverInternal fixationHumansOrthopedics and Sports MedicineOrthodonticsUniversal testing machineOsteosynthesisbusiness.industryAnatomyRadiographySurgeryImplantStress MechanicalbusinessRadius FracturesBone PlatesThe Journal of hand surgery
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Inattentional deafness under dynamic musical conditions

2009

While inattentional blindness is a modern classic in attention and perception research, analogous phenomena of inattentional deafness are less well-known. In music, inattentional deafness has never been demonstrated under controlled experimental conditions, despite of indirect evidence for related effects. We tested inattentional deafness with real music in both musicians and non-musicians. Participants listened to the first 1’50” of Richard Strauss’ Thus Spake Zarathustra, with the experimental group having the task of counting the number of tympani beats and the control group just listening. The unexpected event was an e-guitar solo during the last 20s of this sequence. In Study 1, among …

memory templatescomparisonexpertiseperceptiondual-taskexpectationattention
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From 1D coordination polymers to Metal Organic Frameworks by the use of 2-pyridyl oximes.

2020

The synthesis and characterization of coordination polymers and metal&ndash

metal–organic frameworks (MOFs)MagnetismPolymersdetectioncarboxylatesmixed-ligand02 engineering and technology010402 general chemistry01 natural scienceslcsh:TechnologyArticleMetalchemistry.chemical_compoundPolymer chemistryGeneral Materials Sciencelcsh:Microscopylcsh:QC120-168.85chemistry.chemical_classificationMagnetismeFerric oxidelcsh:QH201-278.5Ligandlcsh:TMagnetismPolymer021001 nanoscience & nanotechnologyOximeMagnetic susceptibility0104 chemical sciencesPolímerscoordination polymerschemistrylcsh:TA1-2040magnetismvisual_artvisual_art.visual_art_mediumencapsulationMetal-organic frameworklcsh:Descriptive and experimental mechanicslcsh:Electrical engineering. Electronics. Nuclear engineeringÒxid de ferropyridyl oximes0210 nano-technologySelectivitylcsh:Engineering (General). Civil engineering (General)lcsh:TK1-9971iron(III)
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A unified formulation for multilayered smart plate advanced models

2017

Magneto-electro-elastic (MEE) composite materials are attracting increasing consideration as they couple mechanical, electrical and magnetic fields and this makes them particularly suitable for smart applications. They are often employed as multilayered configurations that appear to be more effective than bulk MEE composites. Thus, reliable and efficient modelling tools are required for an effective design. The present talk deals with a unified formulation to derive advanced models for multilayered MEE plates. The approach is based on the condensation of the electro-magnetic state into the plate kinematics. This leads to models involving kinematical variables only, which takes the multifiel…

multiphysics multilayered plates smart structuresSettore ING-IND/04 - Costruzioni E Strutture Aerospaziali
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The Retrograde Tibial Nail: presentation and biomechanical evaluation of a new concept in the treatment of distal tibia fractures.

2013

Displaced distal tibia fractures require stable fixation while minimizing secondary damage to the soft tissues by the surgical approach and implants. Antegrade intramedullary nailing has become an alternative to plate osteosynthesis for the treatment of distal metaphyseal fractures over the past two decades. While retrograde intramedullary nailing is a standard procedure in other long bone fractures, only few attempts have been made on retrograde nailing of tibial fractures. The main reasons are difficulties of finding an ideal entry portal and the lack of an ideal implant for retrograde insertion. The Retrograde Tibial Nail (RTN) is a prototype intramedullary implant developed by our group…

musculoskeletal diseasesAdultMalemedicine.medical_specialtymedicine.medical_treatmentLong boneBone NailsOsteotomyProsthesis Designlaw.inventionIntramedullary rodFixation (surgical)lawmedicineHumansTibiaGeneral Environmental ScienceAgedOsteosynthesisbusiness.industryMiddle Agedmusculoskeletal systemSurgeryBiomechanical PhenomenaFracture Fixation IntramedullaryRadiographyTibial Fracturesmedicine.anatomical_structureTreatment OutcomeGeneral Earth and Planetary SciencesFemaleImplantAnklebusinessBone PlatesInjury
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