Search results for "Lee"

showing 10 items of 1847 documents

Age at surgery as a predictor of cognitive improvements in patients with drug-resistant temporal epilepsy

2017

Temporal lobe epilepsy (TLE) surgery is an effective procedure that can produce cognitive changes. However, the prognostic factors related with cognitive outcomes need to be better understood. The aim of the present study is to know if age at surgery is a reliable predictor of verbal memory competence and considering factors such as: hemisphere; type of surgery; pre-surgical seizure frequency; and epilepsy duration. Sixty-one typically dominant patients with drug-resistant TLE (34 with left TLE [L-TLE] and 27 with right TLE [R-TLE]) underwent a neuropsychological assessment before and a year after surgery. Results showed that R-TLE patients had better evolution in short- and long-term verba…

AdultMaleDrug Resistant Epilepsymedicine.medical_specialtyMemory Long-TermDrug resistanceNeuropsychological Testsbehavioral disciplines and activitiesTemporal lobeYoung Adult03 medical and health sciencesBehavioral NeuroscienceEpilepsyCognition0302 clinical medicinePredictive Value of TestsmedicineHumansIn patient030212 general & internal medicineNeuropsychological assessmentEffects of sleep deprivation on cognitive performanceMemory Disordersmedicine.diagnostic_testAge FactorsCognitionMiddle Agedmedicine.diseasenervous system diseasesSurgeryMemory Short-TermEpilepsy Temporal Lobenervous systemNeurologyFemaleNeurology (clinical)Verbal memoryPsychologypsychological phenomena and processes030217 neurology & neurosurgeryEpilepsy & Behavior
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Human sleep under the influence of pulsed radiofrequency electromagnetic fields: A polysomnographic study using standardized conditions

1998

To investigate the influence of radiofrequency electromagnetic fields (EMFs) of cellular phone GSM signals on human sleep electroencephalographic (EEG) pattern, all-night polysomnographies of 24 healthy male subjects were recorded, both with and without exposure to a circular polarized EMF (900 MHz, pulsed with a frequency of 217 Hz, pulse width 577 μs, power flux density 0.2 W/m2. Suppression of rapid eye movement (REM) sleep as well as a sleep-inducing effect under field exposure did not reach statistical significance, so that previous results indicating alterations of these sleep parameters could not be replicated. Spectral power analysis also did not reveal any alterations of the EEG rh…

AdultMaleElectromagnetic fieldmedicine.medical_specialtyanimal structuresAdolescentRadio WavesPhysiologyPolysomnographyAcousticsBiophysicsSleep REMElectroencephalographyAudiologyElectromagnetic FieldsmedicineHumansRadiology Nuclear Medicine and imagingBioelectromagneticsPhysicsmedicine.diagnostic_testPulsed radiofrequencyEye movementElectroencephalographyGeneral MedicineSleep in non-human animalsTelephoneEeg rhythmsPower fluxSleepBioelectromagnetics
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Effects of Pulsed High-Frequency Electromagnetic Fields on Human Sleep

1996

In the present study we investigated the influence of pulsed high-frequency electromagnetic fields of digital mobile radio telephones on sleep in healthy humans. Besides a hypnotic effect with shortening of sleep onset latency, a REM suppressive effect with reduction of duration and percentage of REM sleep was found. Moreover, spectral analysis revealed qualitative alterations of the EEG signal during REM sleep with an increased spectral power density. Knowing the relevance of REM sleep for adequate information processing in the brain, especially concerning mnestic functions and learning processes, the results emphasize the necessity to carry out further investigations on the interaction of…

AdultMaleElectromagnetic fieldmedicine.medical_specialtymedicine.drug_classPolysomnographymedia_common.quotation_subjectRapid eye movement sleepSleep REMAudiologyElectroencephalographyHypnoticElectromagnetic FieldsRisk FactorsmedicineHumansSpectral analysisBiological Psychiatrymedia_commonmedicine.diagnostic_testDose-Response Relationship RadiationSignal Processing Computer-AssistedCognitionTelephonePsychiatry and Mental healthNeuropsychology and Physiological PsychologySleep StagesSleep onset latencyPsychologyVigilance (psychology)Neuropsychobiology
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Push-and-Pull Enteroscopy Using the Double-Balloon Technique (Double-Balloon Enteroscopy) for the Diagnosis of Meckel's Diverticulum in Adult Patient…

2006

Meckel's diverticulum (MD) occurs in 2-3% of the population. Although the clinical, histopathologic, and radiologic features of the complications of MD are well known, the diagnosis may be difficult before surgery.Three patients (age 22-34 yr, two women) presenting with gastrointestinal (GI) bleeding of obscure origin underwent multiple endoscopic and radiologic tests including capsule endoscopy and Tc-99m pertechnetate scintigraphy before push-and-pull enteroscopy using a double-balloon technique (double-balloon enteroscopy). Double-balloon enteroscopy was performed in all three patients using oral and anal approaches to evaluate the entire intestine. In one case, MD was detected using the…

AdultMaleEnteroscopycongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyGastrointestinal bleedingGI bleedingBalloondigestive systemEndoscopy GastrointestinalCatheterizationDouble-balloon enteroscopymedicineHumansMeckel's diverticulumHepatologymedicine.diagnostic_testbusiness.industryGastroenterologymedicine.diseaseSurgeryEndoscopyEndoscopes GastrointestinalMeckel DiverticulumFemaleGastrointestinal HemorrhagebusinessDiverticulumThe American Journal of Gastroenterology
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Impact of fluoroscopy on oral double-balloon enteroscopy: results of a randomized trial in 156 patients

2010

Background and study aims The routine utility of fluoroscopy during double-balloon enteroscopy (DBE) via the oral route has been not prospectively evaluated. Up to now, there have been no prospective randomized trials to assess whether fluoroscopy improves outcomes. The aim of this study was to assess the value of fluoroscopy during oral DBE. Patients and methods A total of 156 patients (88 men, 56.4 %) of mean (standard deviation [SD]) age 56 (19) years were randomly assigned to undergo oral DBE either with or without fluoroscopy. The majority of the patients had obscure gastrointestinal bleeding (n = 96, 62 %). The primary target criteria for the study were postpyloric insertion depth and…

AdultMaleEnteroscopymedicine.medical_specialtyTime FactorsAdolescentlaw.inventionYoung AdultRandomized controlled triallawDouble-balloon enteroscopyHumansMedicineFluoroscopyIn patientProspective StudiesProspective cohort studyAgedAged 80 and overDouble-Balloon EnteroscopyAnalysis of Variancemedicine.diagnostic_testbusiness.industryGastroenterologyMiddle AgedIntestinal DiseasesFluoroscopyFemaleRadiologybusinessAbdominal surgeryObscure gastrointestinal bleedingEndoscopy
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Teacher stress over an autumn term: relationships between subjective stress and catecholamine excretion during night rest

1987

The relationships between subjective stress and catecholamine excretion during night rest were investigated in a group of 137 teachers. The research design was longitudinal and consisted of repeated assessment (six times in an autumn term) of the stress indicators. At the beginning of the term adrenaline excretion rate showed negative and at the end of the term positive correlations with subjective stress feelings. Cluster analysis revealed three stable profile types among the teachers, in which the stress indicators were related to each other in different ways. The subjective stress process was better reflected in noradrenaline excretion than in adrenaline excretion. The findings were inte…

AdultMaleEpinephrinemedia_common.quotation_subjectDevelopmental psychologyExcretionNorepinephrineStress processArts and Humanities (miscellaneous)Rest (finance)Stress (linguistics)Developmental and Educational PsychologymedicineHumansGeneral Psychologymedia_commonTeachingGeneral MedicineMiddle AgedTerm (time)Occupational DiseasesFeelingCatecholamineFemaleSleepEmotional arousalPsychologyStress Psychologicalmedicine.drugScandinavian Journal of Psychology
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Deterministic chaos and the first positive Lyapunov exponent: a nonlinear analysis of the human electroencephalogram during sleep

1993

Under selected conditions, nonlinear dynamical systems, which can be described by deterministic models, are able to generate so-called deterministic chaos. In this case the dynamics show a sensitive dependence on initial conditions, which means that different states of a system, being arbitrarily close initially, will become macroscopically separated for sufficiently long times. In this sense, the unpredictability of the EEG might be a basic phenomenon of its chaotic character. Recent investigations of the dimensionality of EEG attractors in phase space have led to the assumption that the EEG can be regarded as a deterministic process which should not be mistaken for simple noise. The calcu…

AdultMaleGeneral Computer ScienceModels NeurologicalChaoticSystems TheoryLyapunov exponentsymbols.namesakeControl theoryAttractorHumansStatistical physicsMathematicsSleep StagesButterfly effectQuantitative Biology::Neurons and CognitionElectroencephalographyMiddle AgedNonlinear systemData Interpretation StatisticalPhase spaceQuasiperiodic functionsymbolsSleep StagesSleepCyberneticsBiotechnologyBiological Cybernetics
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Clinical efficacy of semiconductor laser application as an adjunct to conventional scaling and root planing.

2005

Background and Objectives: The aim of the in vitro study was to examine the clinical efficacy of semiconductor laser periodontal pocket irradiation as an adjunct to conventional scaling and root planing. Materials and Methods: Twenty-two healthy patients with a need of periodontal treatment (15 women, 7 men, mean age 45.0� 10.8 years) with at least four teeth in all quadrants, were included. All of them underwent a conventional periodontal treatment including scaling and root planing. Using a split mouth design, two randomly chosen quadrants (one upper and the corresponding lower one) were subsequently treated with an 809 nm GaAlAs laser operated at a power output of 1.0 Watt using a 0.6 mm…

AdultMaleGingival and periodontal pocketmedicine.medical_treatmentBleeding on probingDentistryDermatologySensitivity and SpecificityStatistics NonparametricRoot PlaningTooth mobilityScaling and root planingMedicineHumansPeriodontal PocketProspective StudiesLow-Level Light TherapyProspective cohort studySalineProbabilityPeriodontitisbusiness.industryMiddle Agedmedicine.diseaseCombined Modality TherapyTreatment OutcomeClinical attachment lossCase-Control StudiesDental ScalingSurgeryFemalemedicine.symptombusinessFollow-Up StudiesLasers in surgery and medicine
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Sleep quality does not mediate the negative effects of chronodisruption on body composition and metabolic syndrome in healthcare workers in Ecuador

2020

Abstract Background and aims The objective of the present work was to determine to what extent sleep quality may mediate the association between chronodisruption (CD) and metabolic syndrome (MS), and between CD and body composition (BC). Methodology Cross-sectional study which included 300 adult health workers, 150 of whom were night shift workers and thereby exposed to CD. Diagnosis of MS was made based on Adult Treatment Panel III criteria. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Body mass index (BMI), fat mass percentage, and visceral fat percentage were measured as indicators of body composition (BC). Data were analyzed using logistic, linear regression and …

AdultMaleHealth PersonnelEndocrinology Diabetes and MetabolismPhysiologyChronobiology DisordersFat massShift workPittsburgh Sleep Quality Index03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingWork Schedule ToleranceDiabetes mellitusHealth careInternal MedicinemedicineHumans030212 general & internal medicineSDG 7 - Affordable and Clean EnergyExerciseChronobiology PhenomenaMetabolic SyndromeSleep qualitybusiness.industryGeneral MedicineMiddle Agedmedicine.disease030210 environmental & occupational healthCross-Sectional StudiesBody CompositionFemaleEcuadorMetabolic syndromeEnergy IntakeSleepbusinessBody mass indexDiabetes and Metabolic Syndrome: Clinical Research and Reviews
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Preferential splenic CD8+ T-cell activation in rituximab-nonresponder patients with immune thrombocytopenia

2013

The pathogenic role of B cells in immune thrombocytopenia (ITP) has justified the therapeutic use of anti-CD20 antibodies such as rituximab (RTX). However, 60% of ITP patients do not respond to RTX. To decipher the mechanisms implicated in the failure of RTX, and because the spleen plays a well-recognized role in ITP pathogenesis, 12 spleens from ITP patients who had been nonresponders to RTX therapy were compared with 11 spleens from RTX-untreated ITP patients and 9 controls. We here demonstrate that in RTX-nonresponder ITP patients, preferential Th1 and Tc1 T lymphocyte polarizations occur, associated with an increase in splenic effector memory CD8(+) T-cell frequency. Moreover, in the RT…

AdultMaleImmunologyDrug ResistanceSpleenCD8-Positive T-LymphocytesLymphocyte ActivationReal-Time Polymerase Chain ReactionBiochemistryPathogenesisAntibodies Monoclonal Murine-DerivedYoung Adultimmune system diseaseshemic and lymphatic diseasesmedicineHumansImmunologic FactorsCytotoxic T cellAgedAged 80 and overPurpura Thrombocytopenic Idiopathicbiologybusiness.industryCell BiologyHematologyT lymphocyteMiddle AgedImmunohistochemistrymedicine.anatomical_structureImmunologyMonoclonalbiology.proteinFemaleRituximabAntibodyRituximabbusinessSpleenCD8medicine.drugBlood
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