Search results for "Leonotis"

showing 5 items of 5 documents

Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells

2016

Abstract Ethnopharmacological relevance Traditional medicine plays a major role for primary health care worldwide. Cancer belongs to the leading disease burden in industrialized and developing countries. Successful cancer therapy is hampered by the development of resistance towards established anticancer drugs. Aim In the present study, we investigated the cytotoxicity of 29 extracts from 26 medicinal plants of South-Africa against leukemia cell lines, most of which are used traditionally to treat cancer and related symptoms. Material and methods We have investigated the plant extracts for their cytotoxic activity towards drug-sensitive parental CCRF-CEM leukemia cells and their multidrug-r…

0301 basic medicineLeonotis leonurusCell SurvivalPlectranthusPharmacologyMagnoliopsidaSouth Africa03 medical and health sciences0302 clinical medicineCell Line TumorNeoplasmsDrug DiscoveryPlectranthus barbatusmedicineHumansMedicinal plantsMedicine African TraditionalPharmacologyLeonurusPlants MedicinalbiologyPlant ExtractsCancerbiology.organism_classificationmedicine.diseaseAntineoplastic Agents PhytogenicDrug Resistance MultipleLeukemia030104 developmental biologyDrug Resistance Neoplasm030220 oncology & carcinogenesisCancer cellJournal of Ethnopharmacology
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Suitability of a native South African shrub as pot plant

2006

Leonotis leonurus (L.) Br. Pubesc., also known as “lion’s ear” is a perennial shrub belonging to the Labiatae family and native to South Africa. The name of the genus derives from the Greek words leon (lion) and otòs (ear). The esthetic ornamental value of its bright orange inflorescence and its adaptation to a wide range of conditions have led a research to evaluate the suitability of L. leonurus as pot plant. Pot plants from one year rooted cuttings were grown in the Northern coast of Sicily; at the end of December, plants were pruned to 30 cm length and then moved to an unheated plastic greenhouse. Flowering started in April under protected cultivation and continued throughout the summer…

GeographyPot plantved/biologyAgroforestryved/biology.organism_classification_rank.speciesLeonotis leonurus Lion¿s ear ornamental plantForestrySettore AGR/04 - Orticoltura E FloricolturaHorticultureShrub
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Activity against microorganisms affecting cellulosic objects of volatile constituents of Leonotis nepetaefolia from Nicaragua

2014

The chemical composition of the essential oil from aerial parts of L. nepetaefolia (L.) R. Br. collected in Nicaragua was evaluated by GC and GC-MS. The main components were (Z)-phytol (22.8%), caryophyllene oxide (18.9%) and hexahydrofarnesylacetone (9.0%). The antibacterial activity against several Gram + and Gram-bacteria, including Bacillus cereus and B. subtilis, both infesting historical cellulosic material, was also determined. B. cereus, B. subtilis and Staphylococcus epidermis were the most affected by the action of the oil.

LamiaceaeCaryophyllene oxideLeonotis nepetaefoliaVolatile componentsSettore CHIM/06 - Chimica OrganicaSettore BIO/15 - Biologia FarmaceuticaHexahydrofarnesylacetone(Z)-Phytol
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Activity against Microorganisms Affecting Cellulosic Objects of the Volatile Constituents of Leonotis nepetaefolia from Nicaragua

2014

The chemical composition of the essential oil from aerial parts of L. nepetaefolia (L.) R. Br. collected in Nicaragua was evaluated by GC and GC-MS. The main components were ( Z)-phytol (22.8%), caryophyllene oxide (18.9%) and hexahydrofarnesylacetone (9.0%). The antibacterial activity against several Gram + and Gram - bacteria, including Bacillus cereus and B. subtilis, both infesting historical cellulosic material, was also determined. B. cereus, B. subtilis and Staphylococcus epidermis were the most affected by the action of the oil.

MicroorganismBacillus cereusNicaraguaMicrobial Sensitivity TestsPlant ScienceGram-Positive Bacterialaw.inventionBacillus cereusPhytollawVolatile componentGram-Negative BacteriaDrug DiscoveryOils VolatileFood scienceEssential oilPolycyclic SesquiterpenesPharmacologyLamiaceaebiologyTerpenesChemistryfungiLeonotis nepetaefoliadisinfestation of museum objects.General MedicineHexahydrofarnesylacetonebiology.organism_classification(Z)-PhytolAnti-Bacterial AgentsComplementary and alternative medicineCereusCaryophyllene oxideLamiaceaeAntibacterial activitySesquiterpenesBacteriaBacillus subtilisLeonotis
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Structure and Biological Activity of the Furan-Diterpenoids from the Genera Leonotis and Leonurus

2007

The present review, covering the literature up to 2006, reports the chemistry and the biological activities of the diterpenoids occurring in the aerial parts of species belonging to the genera Leonotis and Leonurus, family Lamiaceae.

PharmacologyFamily Lamiaceaenatural productLeonurusLeonuruNatural productbiologyOrganic Chemistrybiological activityBiological activitybiology.organism_classificationAnalytical ChemistryLabdanechemistry.chemical_compoundchemistryFuranLeonotiBotanyLabdaneLeonotisHETEROCYCLES
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