Search results for "Lethal"

showing 10 items of 134 documents

Mini-drones swarms and their potential in conflict situations

2021

Drones are currently used for a wide range of operations, such as border surveillance, general surveillance, reconnaissance, transport, aerial photography, traffic control, earth observation, communications, broadcasting, and armed attacks. This paper examines the swarming and associated abilities to overwhelm a combatant as well as bring extra functionality by means of extra sensors spread throughout the swarm. The strategy of stealth is becoming increasingly less effective. Combatants can not only sense them, but can also successfully destroy them (although this cannot be said for nano-drones). For mini-drones, objectives can be enhanced by the strategy of overwhelming. peerReviewed

Suicide DronesSurveillanceArtificial IntelligenceSwarmingAutonomous DronesSecurityLethal Autonomous Weapons (LAWs)tiedusteluNetworksmiehittämättömät ilma-aluksettekoälysotatekniikkaDrone
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Effect of polybrominated biphenyls on bromobenzene lethality in mice.

1977

Polybrominated biphenyls (PBBs) are inducers of hepatic microsomal cytochrome P450 and P1 450 in rats and mice. The purpose of this study was to determine, in mice, the effect of PBBs on the lethality of the hepatotoxin bromobenzene. Female NMRI mice were administered a single ip injection of 150 mg/kg PBBs and other mice received phenobarbital (PB), 100 mg/kg daily for 3 days, or 3‐methylcholanthrene (MC), 20 mg/kg daily for 3 days. At 24 hr after PB or MC and 24, 48, and 96 hr after PBBs animals received 3,150 mg/kg bromobenzene ip (LD85) and the time to death was recorded. Both PB and MC enhanced bromobenzene lethality and decreased the median time to death (LT50) from 23 hr in controls …

Time FactorsStereochemistryPolybrominated BiphenylsPharmacologyToxicologyLethal Dose 50chemistry.chemical_compoundMicemedicineAnimalsDrug InteractionsbiologyBiphenyl CompoundsHepatotoxinCytochrome P450PollutionGlutathionechemistryLiverBromobenzeneNmri micePhenobarbitalMicrosomebiology.proteinLethalityPhenobarbitalPolybrominated BiphenylsFemalemedicine.drugBromobenzenesMethylcholanthreneJournal of toxicology and environmental health
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Mutagenit�tspr�fung bestrahlter Lebensmittel mit dem ?dominant lethal test?

1973

An insgesamt 716 Ratten und 750 Mausen wurde eine mogliche mutagene Wirkung einer bestrahlten Nahrung gepruft. Fertilitat, Tragezeitdauer, Wurfgrose, Aufzuchtleistung und Geschlechtsverhaltnis zeigten in 5 aufeinanderfolgenden Rattengenerationen keine Storungen in der Reproduktionsfahigkeit an. Es konnte kein Anstieg der Misbildungsrate bei den Rattenfeten beobachtet werden. Auch die Fruchtbarkeit der mannlichen und der weiblichen Tiere der Mausegeneration war ungestort. Durch den “dominant lethal test” an Ratten und Mausen konnte keine embryotoxische oder mutagene Wirkung der bestrahlten Nahrung festgestellt werden, die sich in mit den verwendeten statistischen Methoden erfasbaren Untersch…

ToxicologyDominant lethalGeneticsBiologyMolecular biologyGenetics (clinical)Humangenetik
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Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery

2004

12 páginas, 7 figuras, 1 tabla. Material suplementario en: https://doi.org/10.1016/S0092-8674(03)01025-0. The SUS1 sequences have been deposited in GenBank with the accession number AY278445.

Transcriptional ActivationNucleocytoplasmic Transport ProteinsDNA ComplementarySaccharomyces cerevisiae ProteinsMolecular Sequence DataActive Transport Cell NucleusPorinsRNA polymerase IIBiologyGeneral Biochemistry Genetics and Molecular BiologyFungal ProteinsTranscription (biology)AcetyltransferasesGene Expression Regulation FungalYeastsGene expressionGenes RegulatorTranscriptional regulationAmino Acid SequenceRNA MessengerNuclear proteinPromoter Regions GeneticHistone AcetyltransferasesRegulation of gene expressionCell NucleusBase SequenceBiochemistry Genetics and Molecular Biology(all)Nuclear ProteinsRNA-Binding ProteinsMolecular biologyCell biologySAGA complexRibonucleoproteinsbiology.proteinNuclear PoreGenes LethalChromatin immunoprecipitation
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PGal4 excision reveals the pleiotropic effects of Voila, a Drosophila locus that affects development and courtship behaviour

2001

0016-6723 (Print) Journal Article Research Support, Non-U.S. Gov't; In Drosophila melanogaster, the PGal4 transposon inserted at the chromosomal site 86E1-2 is associated with the Voila1 allele that causes multiple phenotypes. Homozygous Voila1/1 flies rarely reach adulthood and heterozygous Voila1/+ adult males display strong homosexual courtship behaviour. Both normal behavioural and developmental phenotypes were rescued by remobilizing the PGal4 element. Yet, the rescue of heterosexual courtship and of adult viability did not occur in the same strains, indicating that these defects have different genetic origins. Furthermore, many strains showed a partial rescue of both characters. Molec…

Transposable elementMaleHeterozygoteEmbryo Nonmammalianmedia_common.quotation_subjectSexual BehaviorLocus (genetics)Nerve Tissue ProteinsLethalCourtshipSexual Behavior AnimalGeneticsAnimal/*physiologyAnimalsDrosophila ProteinsNerve Tissue Proteins/geneticsAlleleDrosophila melanogaster/*physiologyLarva/*growth & developmentmedia_commonGeneticsNonmammalianbiologyCourtship displayReproductionHomozygoteNuclear ProteinsHeterozygote advantageGeneral MedicineHomosexualitybiology.organism_classificationReproduction/geneticsNuclear Proteins/geneticsSurvival RateDrosophila melanogasterGenesEmbryoLarvaDNA Transposable ElementsGenes LethalFemaleDrosophila melanogaster5' Untranslated RegionsDrosophila ProteinTranscription Factors
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Toxicity of 4-chloro-o-cresol to fish. Light microscopy and chemical analysis of the tissue

1979

TroutChemistryHealth Toxicology and MutagenesisGeneral MedicineToxicologyPollutionLethal Dose 504-chloro-o-cresolCresolsWastewaterEnvironmental chemistryToxicityMicroscopyAnimalsEcotoxicologyFish <Actinopterygii>SalmonidaeBulletin of Environmental Contamination and Toxicology
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Histopathological responses of newly hatched larvae of whitefish (Coregonus lavaretus s.l.) to UV-B induced toxicity of retene

2003

Positively phototactic fish larvae may be exposed to increased ultraviolet-B (UV-B) radiation alone or, potentially and in addition, to polycyclic aromatic hydrocarbons (PAHs) such as retene (7-isopropyl-1-methylphenanthrene) at the egg or larval stages. Suspended and sedimental particulate material near pulp and paper mills may act as sources of retene in chemically contaminated lake areas. In laboratory conditions whitefish larvae were pre-exposed to retene (10, 32 and 100 microg/l), with relevant controls, and irradiated in semi-static tests for 3 h once a day (2 consecutive days) with two UV-B doses (CIE-weighted 2.8 or 5.4 kJ per m(2) per day) or with visible light only. These UV-B dos…

Ultraviolet RaysHealth Toxicology and MutagenesisSunburnAquatic Sciencemedicine.disease_causeMedian lethal doseLethal Dose 50chemistry.chemical_compoundAnimal sciencemedicineAnimalsSalmonidaeSkinPollutantReteneLarvabiologyEcologyPhenanthrenesbiology.organism_classificationLiverchemistryLarvaToxicityIrritationPhototoxicitySalmonidaeWater Pollutants ChemicalAquatic Toxicology
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La teneur hépatique en F4-Neuroprostanes : une variable prédictive majeure de la réduction de la plaque d’athérome

2012

Le fichier annexe contient le livre des résumés; Les propriétés athéroprotectrices des acides gras polyinsaturés de type n-3 à longue chaîne (AGPI n-3 LC), et en particulier de l’acide docosahexaénoique (DHA) ont été largement décrites. Néanmoins, les mécanismes d’action restent encore mal connus. Les recherches se sont récemment orientées vers l’identification des métabolites oxygénés issus des AGPI n-3 LC qui sont de plus en plus considérés comme des effecteurs majeurs de leurs effets athéroprotecteurs. Dans ce contexte, une étude dose-réponse de supplémentation en DHA a été réalisée chez un modèle animal d’athérosclérose (souris LDLR-/-) afin d’étudier les relations entre la progression …

[SDV.AEN] Life Sciences [q-bio]/Food and NutritionDocosahexaenoic acid[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionmedian lethal dose (ld50)acide docosahexaénoiqueeffet dosemécanisme d'action[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionrôle protecteur
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Acute toxicity of some chlorinated phenols, catechols and cresols to trout.

1981

biologyChemistryTroutHealth Toxicology and MutagenesisCatecholsGeneral MedicineToxicologybiology.organism_classificationPollutionAcute toxicityLethal Dose 50TroutCresolsChlorinated phenolsPhenolsEnvironmental chemistryEcotoxicologyAnimalsBiotransformationSalmonidaeChlorophenolsBulletin of environmental contamination and toxicology
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Acute toxicity of several pesticides to rotifer (Brachionus calyciflorus).

1992

biologyHealth Toxicology and MutagenesisRotiferaRotiferGeneral MedicinePesticideToxicologybiology.organism_classificationPollutionMedian lethal doseAcute toxicityToxicologyLethal Dose 50chemistry.chemical_compoundchemistryToxicityBrachionus calyciflorusMalathionAnimalsPesticidesEndosulfanBulletin of environmental contamination and toxicology
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