Search results for "Letters"

Plasmid-mediated QnrS2 determinant from a clinical Aeromonas veronii isolate.

2008

The main objective of this study was to determine the prevalence of the Qnr determinants in clinical and environmental Aeromonas spp. A total of 52 Aeromonas sp. isolates identified by biochemical methods (5), 25 isolated from natural waters (1) and 27 isolated from clinical samples from hospitals in Valencia, Spain, were tested for quinolone resistance by the disk diffusion method (4) (nalidixic acid, 30 μg; oxolinic acid, 2 μg; flumequine, 30 μg; ciprofloxacin, 5 μg; and levofloxacin, 5 μg). Among the studied isolates, 27 showed resistance to nalidixic acid and susceptibility to ciprofloxacin, 24 isolates were susceptible to both nalidixic acid and ciprofloxacin, and only 1, the A. veroni…

“The Divine Magnet: Melville’s Writings to and about Hawthorne”

2017

Neuroticism may reflect emotional variability when correcting for the confound with the mean

2020

Kalokerinos et al. (1) demonstrate that emotional variability, as assessed via the SD, is not significantly associated with neuroticism once the confound with mean negative emotion is controlled for, r = 0.05. To control for this confound, the authors use the relative SD (RSD), which mathematically corrects for the nonlinear dependency between the SD and the mean (2). The authors prefer the RSD over including the SD and the mean of negative emotions in a model, given the nonlinearity of their association. While we agree that the RSD is an important addition to the field, we argue that including the mean of emotions is still necessary when examining the association between neuroticism and em…

Elotuzumab, lenalidomide, and dexamethasone as salvage therapy for patients with multiple myeloma: Italian, multicenter, retrospective clinical exper…

2020

No abstract available

Best practice in research – Overcoming common challenges in phytopharmacological research

2019

Abstract Background The pharmacology, toxicology and pharmacokinetics of bioactive preparations derived from natural sources has become a flourishing field of research. However, researching complex extracts and natural products faces numerous challenges. More broadly in recent years the critique of pharmacological research, and specifically its design, the methods used and reporting has intensified. Aims This consensus document provides a perspective on what constitutes best practice in pharmacological research on bioactive preparations derived from natural sources, providing a perspective of what the leading specialist journals in the field consider as the core characteristics of good rese…

Pregabalin in the Treatment of Refractory Bipolar Disorders

2012

¡Qué quejicosos! Buzón de quejas a través del aprendizaje cooperativo

2017

Resumen: En este artículo se ofrece una experiencia práctica enmarcada dentro del aprendizaje cooperativo, que crea una interdependencia positiva propicia para el aprendizaje. Para ello, después de una breve aproximación teórica al aprendizaje cooperativo, la argumentación y los actos de habla de queja, así como del género textual «carta de reclamación», se expone la propuesta de nivel B2 organizada en diferentes pasos: la selección de equipos, el análisis de cartas de reclamación, la modificación de los equipos, la asignación de roles, así como la escritura de cartas y posterior evaluación. Se trabajan distintas destrezas, además de conseguir que los alumnos interactúen como en la vida rea…

Opinions about people with schizophrenia among medical students: Findings from an Italian cross-sectional study.

2020

Background: Accumulating evidence suggests that stigmatisation toward people with schizophrenia (PWS) is common among healthcare professionals and represents a major barrier to care. Aim: The study aimed at comparing the opinions about PWS among Italian medical students at different stages of education. Methods: Study participants were 234 medical students, attending either the first three-years pre-clinical or the following three-years clinical stage. Participants read an unlabelled case-vignette of schizophrenia and completed the Opinions on Mental Illness Questionnaire. Results: A greater proportion of students at the clinical stage identified schizophrenia in the clinical description, c…

Weak D and partial D: our experience in daily activity

2011

Visual hallucinations and agitation in Alzheimer's Disease due to memantine: report of three cases

2007

Memantine, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, is currently the only drug proposed for the treatment of moderate to severe Alzheimer’s disease.1 It has been shown to have neuroprotective effects by inhibiting the excitotoxic effect of NMDA glutamate receptors.2 Memantine has a tolerability profile similar to placebo.1 However, the worsening of psychotic symptoms in patients with Lewy body dementia (LBD) treated with memantine has been recently reported.3 We describe three patients with probable Alzheimer’s disease who developed worsening or de novo visual hallucinations and agitation after memantine treatment. Patient 1 was a 65-year-old woman with a 2-year hi…