Search results for "Liability"
showing 10 items of 1754 documents
Next generation diagnostic algorithm in non-small cell lung cancer predictive molecular pathology: The KWAY Italian multicenter cost evaluation study
2022
Abstract Aims The KWAY project aims to investigate the economic sustainability of the up-front NGS technologies adoption in the analysis of clinically relevant molecular alterations in NSCLC patients. Methods The diagnostic workflow and the related sustained costs of five Italian referral centers were assessed in four different evolving scenarios were analyzed. For each scenario, two alternative testing strategies were evaluated: the Maximized Standard strategy and the Maximized NGS strategy. Results For each center, the robustness of obtained results was verified through a deterministic sensitivity analysis, observing the variation of total costs based on a variation of ±20 % of the input …
Psychometric properties of the parental bonding instrument in a Spanish sample.
1993
The Parental Bonding Instrument was translated into Spanish and administered to a sample of 205 Spanish primiparae 3 days after childbirth. Reliability, factorial structure and predictive validity for affective disorders were evaluated. The Spanish version of the PBI has psychometric features similar to those described in other cultures. However, the results suggest that in future research the predictive power of the “Control” factor in affective disorders might be improved by splitting it into two subfactors: “Overprotection” and “Restraint”.
Summary and recommendations of the OARSI FDA osteoarthritis Assessment of Structural Change Working Group
2011
Import JabRef | WosArea Orthopedics; Rheumatology; International audience; Objective: The Osteoarthritis Research Society International initiated a number of working groups to address a call from the US Food and Drug Administration (FDA) on updating draft guidance on conduct of osteoarthritis (OA) clinical trials. The development of disease-modifying osteoarthritis drugs (DMOADs) remains challenging. The Assessment of Structural Change (ASC) Working Group aimed to provide a state-of-the-art critical update on imaging tools for OA clinical trials. Methods: The Group focussed on the performance metrics of conventional radiographs (CR) and magnetic resonance imaging (MRI), performing systemati…
A questionnaire to assess parental perception of barriers towards active commuting to school (PABACS): Reliability and validity
2019
Abstract Introduction Parental barriers are a key factor to determine physical activity behaviors, such as active commuting to school in young people. The purpose of this study was to test the reliability and validity of a questionnaire which addresses parental barriers towards active commuting to school. Methods This paper describes the development, following the Delphi method, and the validation of a Likert-scale questionnaire of 23 items (Parental Perception of Barriers towards Active Commuting to School (PABACS)) designed to determine the main parental barriers. These barriers are categorized into 3 scales (general, walking, and cycling barriers) and the overall questionnaire. A total o…
Refinement and validation of a comprehensive scale for measuring HR practices aimed at performance-enhancement and employee-support
2019
Abstract The purpose of this paper is to refine and validate a Human Resource practices (HRP) scale to measure employees' perceptions and test a two-tier model structured in eight practices and two bundles. In a sample of 554 employees, an EFA (Exploratory Factor Analysis) offered six factors that explained about 70% of the variance. Then, with 1647 employees (from 41 Spanish organizations), first- and second-order models were tested with Confirmatory Factor Analysis (CFA). The former encompasses eight practices. The latter grouped the practices in two bundles, one on enhancing performance and the other on supporting employees. The Cronbach's alpha, Rho coefficient (Composite Reliability Co…
Spanish validation of the Servant Leadership Short Scale for young adults and adolescents / Validación de la Escala de Liderazgo de Servicio Versión …
2017
AbstractThe aim of the current study was to validate a shortened Spanish version of the Servant Leadership Profile (SLP). In Study 1, a number of experts evaluated and reduced the original scale to 14 items and named the revised version the Servant Leadership Short Scale (SLSS). An exploratory factor analysis conducted with a sample of 1,001 students revealed two possible structure solutions, a one-factor solution and a two-correlated factor solution. Study 2 used a different sample of 456 students to examine the explored structures using confirmatory factor analysis. A one-factor solution was proposed (χ2/df = 3.4, CFI = .91, TLI = .90, RMSEA = .07, SRMR = .06). Finally, in Study 3, servan…
The Narcissistic Personality Inventory 8: Validation of a Brief Measure of Narcissistic Personality
2020
The present study was conducted with the aim of constructing and validating a short form of the Narcissistic Personality Inventory (NPI). The NPI is the most widely-applied measure for the assessment of narcissistic personality traits and, therefore, it is of great relevance for many research questions in personality and social psychology. To develop the short scale, we first found the optimal eight-item solution among all valid combinations of the NPI-15 items in an exploratory subsample (n = 1,165) of our complete representative sample of the German general population. We then validated this model in a confirmatory subsample (n = 1,126). Additionally, we examined its invariance across age…
Comparative evaluation of three semi-quantitative radiographic grading techniques for knee osteoarthritis in terms of validity and reproducibility in…
2008
OBJECTIVE: The objective of this work was to compare the measurement properties of three categorical X-ray scoring methods of knee osteoarthritis (OA), both on semiflexed and extended views. METHODS: In data obtained from trials and cohorts, X-rays were graded using Kellgren and Lawrence (KL), the OA Research Society International (OARSI) joint space narrowing score, and measurement of joint space width (JSW). JSW was analyzed as a categorical variable. Construct validity was assessed through logistic regression between X-ray stages and Western Ontario and McMaster Universities OA Index. Inter-observer reliability was assessed in 50 subjects for extended views by weighted kappa. Intra-obser…
The Fit for Delivery study: rationale for the recommendations and test-retest reliability of a dietary score measuring adherence to 10 specific recom…
2012
Aiming at preventing excessive weight gain during pregnancy, 10 specific dietary recommendations are given to pregnant women in the intervention arm of the Norwegian Fit for Delivery (FFD) study. This paper presents the rationale and test-retest reliability of the food frequency questionnaire (FFQ) and a dietary score measuring adherence to the recommendations. The study is part of the ongoing FFD study, a randomised, controlled, intervention study in nulliparous pregnant women. A 43-item FFQ was developed for the FFD study. A dietary score was constructed from 10 subscales corresponding to the 10 dietary recommendations. Adding the subscales yielded a score from 0 to 10 with increasing sco…
Comparison between Different Dynamic Reconfigurations of Electrical Connections for partially shaded PV Modules
2018
This paper presents an economical investigation on the benefits related to the employment of reconfiguration systems for photovoltaic plants. More in detail, different structures of reconfigurators are proposed and, in order to evaluate the economical convenience on their installation, the Net Present Value is used as a validation element. Significant results are carried out from the proposed analysis.