Search results for "Liber"
showing 10 items of 1718 documents
Diritto naturale e liberalismo. Dialogo o conflitto?
2009
Confronto fra diritto naturale e liberalismo in tema di rule of law e di etica delle virtù
“Cittadinanza europea e liberalismo nazionale”
2007
L'articolo tratta il tema dell'interpretazione dell'istituto della cittadinanza europea offerte dalle teorie del c.d. "nazionalismo liberale". Dopo avere sommariamente introdotto i caratteri della cittadinanza europea e dopo avere evidenziato la modificazione dei concetti di nazione e nazionalismo, nell'articolo si presentano i punti di forza e di debolezza di questa interpretazione, con particolare attenzione alle dottrine offerte da N. MacCormick e Joseph Weiler.
La dote, il ius singulare e il ‘sistema didattico’ di Gaio
2016
This paper discusses the idea that the gap regarding the dowry in Gaius’ Institutes is due to the fact that Gaius intentionally did not deal with this subject because he considered it as 'ius singulare' and that this omission was filled in by a 'liber singularis' outside the Institutes. The existence of a "didactic system" made up of the Gaius’ Institutes and four 'libri singulares' for the classical age of Roman Law is also disputed.
The End of Tourism as We Know It
2019
The present chapter posits an interesting discussion revolving around the term Thana Capitalism, which was originally formulated in earlier works. Originally formulated to serve as an opposite alternative against neo-pragmatism, neoliberalism toyed with the belief that the world can be united through the consumption and free trade. During 80s and 90s decades, the theory of development adopted tourism as an efficient instrument to struggle with poverty. Under the auspices of neoliberalism, modern tourism not only paved the ways for an “Kantian eternal peace,” but also conducted a much deeper process of democratization beyond the borders of Western civilization. After the recent, stock market…
Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves.
1995
Abstract This study was designed to elucidate whether nitric oxide (NO) controls norepinephrine (NE) release from sympathetic nerves of the rat heart. Hearts were perfused in the Langendorff mode with Tyrode’s solution. The right sympathetic nerve was stimulated with trains of 1 or 3 Hz and NE release was measured. The NO synthase (NOS) inhibitor N G -nitro- l -arginine (L-NNA) enhanced the evoked NE release in a concentration-dependent manner. This facilitation was independent of the increase in perfusion pressure and was stereospecifically reversed by l -arginine but not d -arginine. Another NOS inhibitor, N G -methyl- l -arginine, produced a similar increase in NE release. The NO-donor …
La proposta di Direttiva Bolkestein fra nuove esigenze e paure di innovazione
2006
By the beginning of this year, EU institutions are approving a proposal of directive on the internal market services liberalization. It is probably the last important step along the path of european economic integration, started in 1957 with the Treaty of Rome. The proposal has not yet an easy pattern, above all for the "country of origin principle". This principle is seen by the supporters as an important tool to speed up the process, but by the opponents as a way to favour possible bottom races for social standards, due to a competition based exclusively upon the employment factor. A basic question is what it will remain at the end of the day, after revisions, corrections, integrations th…
Le infrastrutture di telecomunicazioni: quale semplificazione amministrativa?
2009
Analisi delle ambivalenze della nozione di semplificazione riferita alle infrastrutture di telecomunicazioni
Nanoassemblies Based on Supramolecular Complexes of Nonionic Amphiphilic Cyclodextrin and Sorafenib as Effective Weapons to Kill Human HCC Cells
2015
Sorafenib (Sor), an effective chemiotherapeutic drug utilized against hepatocellular carcinoma (HOC), robustly interacts with nonionic amphiphilic cyclodextrin (aCD, SC6OH), forming, in aqueous solution, supramolecular complexes that behave as building blocks of highly water-dispersible colloidal nanoassemblies. SC6OH/Sor complex has been characterized by complementary spectroscopic techniques, such as UV-vis, steady-state fluorescence and anisotropy, resonance light scattering and H-1 NMR. The spectroscopic evidences and experiments carried out in the presence of an adamantane derivative, which competes with drug for CD cavity, agree with the entrapment of Sor in aCD, pointing out the role…
Lipid nanocarriers containing sorafenib inhibit colonies formation in human hepatocarcinoma cells
2015
Here, the potential of two nanostructured lipid carriers (NLC) for controlled release of sorafenib was evaluated. The obtained systems showed characteristics suitable as drug delivery systems for the treatment of hepatocellular carcinoma (HCC) through parenteral administration. The use of a mixture between a solid lipid (tripalmitin) with a liquid lipid (Captex 355 EP/NF or Miglyol 812) to prepare NLC systems could give a higher drug loading capacity and a longer term stability during storage than that obtained by using only solid lipids. The obtained nanoparticles showed a nanometer size and high negative zeta potential values. Scansion electron microscopy (SEM) of the sorafenib loaded NLC…
Designing robust immediate release tablet formulations avoiding food effects for BCS class 3 drugs
2019
Abstract Food induced viscosity in the gastrointestinal tract is reported to reduce the bioavailability of tablets containing BCS class 3 drugs, mainly by retarding their disintegration and dissolution of the active pharmaceutical ingredient. The role of formulation factors in minimizing this negative food effect is largely unknown. Combinations of disintegrants were studied together with soluble and insoluble fillers and trospium chloride as model drug substance. Different batches of tablets were compressed at 10 kN and 30 kN, by incorporating different combinations of croscarmellose sodium (CSS), cross-linked (CPD) and sodium starch glycolate (SSG) at low level i.e, 2% + 2% and high level…