Search results for "Library"

"Design and application of a data-independent precursor and product ion repository."

2012

The functional design and application of a data-independent LC-MS precursor and product ion repository for protein identification, quantification, and validation is conceptually described. The ion repository was constructed from the sequence search results of a broad range of discovery experiments investigating various tissue types of two closely related mammalian species. The relative high degree of similarity in protein complement, ion detection, and peptide and protein identification allows for the analysis of normalized precursor and product ion intensity values, as well as standardized retention times, creating a multidimensional/orthogonal queryable, qualitative, and quantitative spac…

Building high-quality assay libraries for targeted analysis of SWATH MS data

2015

Targeted proteomics by selected/multiple reaction monitoring (S/MRM) or, on a larger scale, by SWATH (sequential window acquisition of all theoretical spectra) MS (mass spectrometry) typically relies on spectral reference libraries for peptide identification. Quality and coverage of these libraries are therefore of crucial importance for the performance of the methods. Here we present a detailed protocol that has been successfully used to build high-quality, extensive reference libraries supporting targeted proteomics by SWATH MS. We describe each step of the process, including data acquisition by discovery proteomics, assertion of peptide-spectrum matches (PSMs), generation of consensus sp…

Exploration of the Sea Urchin Coelomic Fluid via Combinatorial Peptide Ligand Libraries

2012

The urchin Paracentrotus lividus has been characterized via previous capture and enhancement of low-abundance proteins with combinatorial peptide ligand libraries (CPLL, ProteoMiner). Whereas in the control only 26 unique gene products could be identified, 82 species could be detected after CPLL treatment. Due to the overwhelming presence of two major proteins-the toposome (a highly glycosylated, modified calcium-binding, iron-less transferrin) and the major yolk proteins, belonging to the class of cell adhesion proteins-which constituted about 70% of the proteome of this biological fluid and strongly interfered with the capture of the minority proteome, no additional proteins could be dete…

A study protocol: evaluating the natural experiment of free school fruit in Norway (2007-14)

2017

Changer les attitudes contre la violence de genre: culture, éducation et apprentissage mutuels.

2017

International audience; Cet article interroge la notion de genre et ses acceptions multiples. Nous allons d’abord nous interroger sur cette notion pour comprendre les dynamiques de sa construction et de son évolution. Ensuite nous allons la lier avec le terme de «violence» et de ses différentes déclinaisons qui seront expliquées à travers l’élucidation des cas particuliers comme les centres antiviolence dans le Sud de l’Italie.This article examines the concept of gender and its multiple meanings. First we will ask what that concept for understanding the dynamics of its construction and its evolution. Then we will link it with the term "violence" and its different mean-ings that will be expl…

Autocitas de revistas incluidas en una misma categoría temática del Clarivate Journal Citation Reports (JCR): el caso de la revista Adicciones

2022

El objetivo del presente estudio es determinar si el criterio impuesto por Clarivate Analytics de penalizar las revistas que tengan un elevado número de autocitas debería aplicarse a todas las revistas por igual, sin considerar indicadores bibliométricos diferenciales entre revistas. Se analizaron las características editoriales de la revista Adicciones, la cual fue excluida del JCR del 2019 por un exceso de autocitas, frente a las revistas de su misma categoría, y diferentes indicadores bibliométricos de la revista Adicciones. Los resultados indican características editoriales diferentes entre las publicaciones incluidas en la categoría Substance Abuse del JCR según país de edición, número…

Outcomes‐based measurement of public access computing in public libraries

2010

PurposeThis paper seeks to present a methodology for measuring the outcomes of public access computing as well as presenting and comparing the main results of baseline studies conducted in Lithuania and Latvia.Design/methodology/approachBoth baseline studies use a combination of quantitative and qualitative methods and both include multi‐perspective, longitudinal design and nation‐wide samples.FindingsThe benefits that users can gain from using PAC in public libraries include access to ICT, technology training and assistance, expanded employment opportunities, conducting commercial transactions, access to and assistance with local, state and federal government electronic services, and suppo…

Trust and social capital in teams and organizations — antecedents, dynamics, benefits and limitations: an introduction

2009

Bibliometric analysis of the scientific production in implantology (2009-2013).

2016

Objectives To quantify, using bibliometric indicators, the scientific productivity of researchers, organizations, and countries, publishing articles on implantology in dental journals indexed in Journal Citation Reports between 2009 and 2013. Materials and methods Published texts were identified by applying the truncated search term “implant*.” Document type was limited to “Article.” Records were manually refined and normalized to unify terms and to remove typographical, transcription, and/or indexing errors. Results A total of 6088 articles were located. A progressive increase in the rate of publication was observed, especially between 2010 and 2012. This increase was clearly linked to inc…

[Archivos de Bronconeumología: among the 3 Spanish medical journals with the highest national impact factors].

2004

bConselleria de Sanitat, Generalitat Valenciana, Valencia, Spain. OBJECTIVE: Citation analysis elucidates patterns of information consumption within professional communities. The aim of this study was to analyze the citations of 87 Spanish medical journals by calculating their impact factors and immediacy indices for 2001, and to estimate the importance of ARCHIVOS DE BRONCONEUMOLOGIA within the framework of Spanish medicine. MATERIAL AND METHOD: Eighty-seven Spanish medical journals were included. All were listed in the Spanish Medical Index (Indice Medico Espanol) and in at least one of the following databases: MEDLINE, BIOSIS, EMBASE, or Science Citation Index. References to articles fro…